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1.
Nanoscale Horiz ; 5(11): 1487-1495, 2020 Oct 26.
Artigo em Inglês | MEDLINE | ID: mdl-32945326

RESUMO

One of the most important research topic in optics and photonics is the design of metasurfaces to substitute conventional optical elements that demonstrate unprecedented merits in terms of performance and form factor. In this context, full-space control of metasurfaces that makes it possible to manipulate scattered light in transmission and reflection spaces simultaneously, is proposed as the next-generation scheme in optics, with a potential for applications such as 360° holographic images and novel optical systems. However, previously designed metasurfaces lacked functionality because the desired operation occurs under preconditioned light; therefore, they are difficult to use in real applications. Here, we present a design method that enables polarization-dependent full-space control, in which two independent and arbitrary phase profiles can be addressed to each space. Upon introducing a phase gradient value to realize the critical angle condition, conversion of transmissive into reflective operation is realized. Then, rectangular nanopillars are utilized to facilitate polarization beam splitting with the desired phase. Three samples were fabricated and measured based on the proposed scheme.

2.
Nanoscale Horiz ; 5(7): 1088-1095, 2020 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-32377648

RESUMO

Dynamically reconfigurable nanoscale tuning of visible light properties is one of the ultimate goals both in the academic field of nanophotonics and the optics industry demanding compact and high-resolution display devices. Among various efforts incorporating actively reconfigurable optical materials into metamaterial structures, phase-change materials have been in the spotlight owing to their optical tunability in wide spectral regions including the visible spectrum. However, reconfigurable modulation of visible light intensity has been limited with small modulation depth, reflective schemes, and a lack of profound theoretical background for universal design rules. Here, all-dielectric phase-change Fano metasurface gratings are demonstrated for strong dynamic full-space (reflection and transmission) modulation of visible intensities based on Fano resonances. By judicious periodic couplings between densely arranged meta-atoms containing VO2, phase-change induced thermo-optic modulation of full-space intensities is highly enhanced in the visible spectrum. By providing intuitive design rules, we envision that the proposed study would contribute to nanophotonics-enabled optoelectronics technologies for imaging and sensing.

3.
Sci Rep ; 9(1): 15381, 2019 Oct 25.
Artigo em Inglês | MEDLINE | ID: mdl-31653951

RESUMO

Nano-structural colour pixels have attracted much attention as promising solutions for compact display devices. However, it is difficult to miniaturize and integrate conventional transmissive colour filtering components for high resolution pixels within subwavelength scale without sacrificing colour depth. Here, we propose a novel colour pixel structure using bi-layered hybrid metasurfaces that are composed of aluminum nanograting and amorphous silicon nanorod layers. The independent high-contrast control of resonance intensity and spectral position is achieved by anisotropic Mie resonances and cavity effect between stacked two metasurfaces. Moreover, the proposed structures permit the wide colour gamut through the novel physical principles. In addition, a meta-pixel which can provide gradual tuning of colour is demonstrated to obtain high colour depth. The proposed structures are expected to be fruitful for the development of next generation display and imaging systems.

4.
Opt Express ; 26(8): 10649-10660, 2018 Apr 16.
Artigo em Inglês | MEDLINE | ID: mdl-29715998

RESUMO

We investigate Huygens' optical vector wave field synthesis scheme for electric dipole metasurfaces with the capability of modulating in-plane polarization and complex amplitude and discuss the practical issues involved in realizing multi-modulation metasurfaces. The proposed Huygens' vector wave field synthesis scheme identifies the vector Airy disk as a synthetic unit element and creates a designed vector optical field by integrating polarization-controlled and complex-modulated Airy disks. The metasurface structure for the proposed vector field synthesis is analyzed in terms of the signal-to-noise ratio of the synthesized field distribution. The design of practical metasurface structures with true vector modulation capability is possible through the analysis of the light field modulation characteristics of various complex modulated geometric phase metasurfaces. It is shown that the regularization of meta-atoms is a key factor that needs to be considered in field synthesis, given that it is essential for a wide range of optical field synthetic applications, including holographic displays, microscopy, and optical lithography.

5.
Opt Express ; 26(26): 34641-34654, 2018 Dec 24.
Artigo em Inglês | MEDLINE | ID: mdl-30650885

RESUMO

Ultra-compact dynamically reconfigurable modulation of optical transmission has been widely studied by using subwavelength-spaced resonant metasurface structures containing reconfigurable optical materials. However, it has been difficult to achieve high transmissivity, large modulation depth, and broad bandwidth simultaneously with the conventional resonance-based metasurface schemes. Here, we propose a reconfigurable phase-transition diffractive grating, made of thick VO2 ridge waveguides, for achieving the above-mentioned three goals simultaneously in the near-infrared range. Based on the large dielectric-to-plasmonic transition characteristic of VO2 in the near-infrared range, diffraction directivity of dual-VO2 ridge waveguide is designed to be tuned by thermally driven phase transition of VO2 for transverse electrically polarized illumination. Then, the diffractive VO2 ridge waveguide grating composed of the periodically arranged dual VO2 ridge waveguides is designed with on-state efficiency around 0.3 and minimum modulation depth about 0.35 over a broad bandwidth of 550 nm (1100-1650 nm). The working principle and excellent modulation performance are thoroughly verified through numerical and experimental studies.

6.
PLoS One ; 8(1): e52931, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-23301003

RESUMO

BACKGROUND: Cancer stem cells (CSCs) are highly tumorigenic and are responsible for tumor progression and chemoresistance. Noninvasive imaging methods for the visualization of CSC populations within tumors in vivo will have a considerable impact on the development of new CSC-targeting therapeutics. METHODOLOGY/PRINCIPAL FINDINGS: In this study, human breast cancer stem cells (BCSCs) transduced with dual reporter genes (human ferritin heavy chain [FTH] and enhanced green fluorescence protein [EGFP]) were transplanted into NOD/SCID mice to allow noninvasive tracking of BCSC-derived populations. No changes in the properties of the BCSCs were observed due to ferritin overexpression. Magnetic resonance imaging (MRI) revealed significantly different signal intensities (R(2)* values) between BCSCs and FTH-BCSCs in vitro and in vivo. In addition, distinct populations of pixels with high R(2)* values were detected in docetaxel-treated FTH-BCSC tumors compared with control tumors, even before the tumor sizes changed. Histological analysis revealed that areas showing high R(2)* values in docetaxel-treated FTH-BCSC tumors by MRI contained EGFP+/FTH+ viable cell populations with high percentages of CD44+/CD24- cells. CONCLUSIONS/SIGNIFICANCE: These findings suggest that ferritin-based MRI, which provides high spatial resolution and tissue contrast, can be used as a reliable method to identify viable cell populations derived from BCSCs after chemotherapy and may serve as a new tool to monitor the efficacy of CSC-targeting therapies in vivo.


Assuntos
Neoplasias da Mama/tratamento farmacológico , Ferritinas/química , Taxoides/farmacologia , Animais , Antineoplásicos/farmacologia , Membrana Celular/metabolismo , Suplementos Nutricionais , Progressão da Doença , Docetaxel , Resistencia a Medicamentos Antineoplásicos , Feminino , Proteínas de Fluorescência Verde/metabolismo , Humanos , Imuno-Histoquímica/métodos , Ferro/farmacologia , Imageamento por Ressonância Magnética/métodos , Camundongos , Camundongos Endogâmicos NOD , Camundongos SCID , Células-Tronco Neoplásicas/citologia
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