1.
Arch Pathol Lab Med
; 127(3): e119-22, 2003 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12653597
RESUMO
Hepatosplenic T-cell lymphoma is an uncommon neoplasm characterized by a lymphoid infiltrate within the sinusoids of the liver, spleen, and bone marrow, without significant nodal involvement. The majority of cases express the gammadelta T-cell receptor and are associated with an isochromosome 7q cytogenetic abnormality. Recently, a small number of cases have been reported that express the alphabeta T-cell receptor. Here, we report our findings of a case of an S100-positive hepatosplenic alphabeta T-cell lymphoma in a 20-year-old woman who presented with pancytopenia and hepatosplenomegaly. The case adds to the growing literature of hepatosplenic alphabeta T-cell lymphomas.
Assuntos
Neoplasias Hepáticas/diagnóstico , Neoplasias Hepáticas/genética , Linfoma de Células T/diagnóstico , Linfoma de Células T/genética , Receptores de Antígenos de Linfócitos T alfa-beta/genética , Proteínas S100/biossíntese , Neoplasias Esplênicas/diagnóstico , Neoplasias Esplênicas/genética , Adulto , Feminino , Humanos , Receptores de Antígenos de Linfócitos T alfa-beta/biossíntese , Proteínas S100/genética
2.
Cancer Genet Cytogenet
; 136(2): 153-4, 2002 Jul 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12237243