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IEEE Trans Biomed Eng ; 48(4): 425-33, 2001 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-11322530

RESUMO

This study investigated the flow effect on the lesion formation during radio-frequency cardiac catheter ablation in temperature-controlled mode. The blood flow in heart chambers carries heat away from the endocardium by convection. This cooling effect requires more power from the ablation generator and causes a larger lesion. We set up a flow system to simulate the flow inside the heart chamber. We performed in vitro ablation on bovine myocardium with three different flow rates (0 L/min, 1 L/min and 3 L/min) and two target temperatures (60 degrees C and 80 degrees C). During ablation, we also recorded the temperatures inside the myocardium with a three-thermocouple temperature probe. The results show that lesion dimensions (maximum depth, maximum width and lesion volume) are larger in high flow rates (p<0.01). Also, the temperature recordings show that the tissue temperature rises faster and reaches a higher temperature under higher flow rate.


Assuntos
Ablação por Cateter/métodos , Hemodinâmica/fisiologia , Modelos Cardiovasculares , Animais , Procedimentos Cirúrgicos Cardíacos/métodos , Bovinos , Miocárdio/patologia
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