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1.
Ugeskr Laeger ; 185(24)2023 06 12.
Artigo em Dinamarquês | MEDLINE | ID: mdl-37325986

RESUMO

This is a case report of a Ukrainian war-injured patient who was colonised/infected with nine different carbapenemase-producing organisms (CPO). The patient was initially treated in Ukraine. After two months he was admitted to a Danish hospital where he underwent extensive surgery and received broad-spectrum antibiotics. In screening and clinical samples, nine different CPO were cultured which in combination were untreatable with antibiotics. To our knowledge, this is the first patient in Denmark with such a high number of different CPO. This may be a sign that we are entering a postantibiotic era.


Assuntos
Proteínas de Bactérias , beta-Lactamases , Masculino , Humanos , Antibacterianos/uso terapêutico
2.
Ugeskr Laeger ; 184(27)2022 07 04.
Artigo em Dinamarquês | MEDLINE | ID: mdl-35786497

RESUMO

In this case report a rare case of Ureaplasma parvum arthritis affecting the left knee, hip, and the sacroiliac joint in a 57-year-old woman is investigated. The patient was initially treated with intravenous piperacillin/tazobactam and later on meropenem with no clinical effect. After surgery of the hip and knee, tissue biopsies and synovial fluids were all culture negative. Eventually, Ureaplasma parvum was detected by 16S analysis, and the antibiotic regimen was changed to intravenous moxifloxacin. The patient improved and after four weeks the therapy was changed to lifelong oral therapy with moxifloxacin.


Assuntos
Artrite , Ureaplasma , Feminino , Humanos , Articulação do Joelho/cirurgia , Pessoa de Meia-Idade , Moxifloxacina , Articulação Sacroilíaca/diagnóstico por imagem
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