RESUMO
Through an interplay between density functional calculations, Monte Carlo simulations and scanning tunneling microscopy experiments, we show that an intermediate coverage of CO on the Pt(110) surface gives rise to a new rough equilibrium structure with more than 50% step atoms. CO is shown to bind so strongly to low-coordinated Pt atoms that it can break Pt-Pt bonds and spontaneously form steps on the surface. It is argued that adsorption-induced step formation may be a general effect, in particular at high gas pressures and temperatures.
RESUMO
Approximately one-third of patients with glioblastoma multiforme experience aphasia (Kraemer & Bullard, 1994). This loss of language abilities can be a major source of frustration for patients. Their quality of life is affected by the inability to interact with others. In this paper, an examination of the phenomenon of expressive aphasia will be conducted through the application of the content methodology process. Content methodology is a process for developing nursing knowledge, which strives to bridge the gap between theory, research and practice (Dawson & Wells, 1992). This process will guide in the development of substantive content for practice. An assessment tool and intervention plan will be presented.
Assuntos
Afasia de Broca , Neoplasias Encefálicas/complicações , Glioblastoma/complicações , Pesquisa Metodológica em Enfermagem/métodos , Qualidade de Vida , Afasia de Broca/etiologia , Afasia de Broca/enfermagem , Afasia de Broca/psicologia , Humanos , Avaliação em Enfermagem/métodos , Enfermagem Oncológica , Planejamento de Assistência ao Paciente , Psicometria , Reprodutibilidade dos TestesAssuntos
Doenças Ósseas/diagnóstico por imagem , Adolescente , Adulto , Idoso , Neoplasias Ósseas/diagnóstico por imagem , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Masculino , Pessoa de Meia-Idade , Cintilografia , TecnécioAssuntos
Diabetes Mellitus/tratamento farmacológico , Compostos de Sulfonilureia/uso terapêutico , Tolbutamida/uso terapêutico , Adulto , Idoso , Glicemia , Peso Corporal , Ensaios Clínicos como Assunto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Compostos de Sulfonilureia/efeitos adversos , Tolbutamida/efeitos adversosRESUMO
A brief review is given of the pharmacological data of verapamil, which chemically shows a certain similarity to papaverine. The effect of the drug (80 mg) 3 times daily, on angina pectoris, as compared with placebo, was evaluated in a double-blind cross-over therapeutic trial with 4-wk periods in 47 patients. The incidence of attacks and the nitroglycerine consumption decreased in the second fortnight of the verapamil period by approximately 25% compared with the placebo period. An ergometer test showed a prolongation of the exerice time of 20%. The mean blood pressure and the heart rate fell under verapamil treatment if the patients had values which were relatively high in the placebo period. The increase in heart rate during exercise from two different resting levels showed a tendency to become more pronounced under treatment with verapamil than under placebo. The length of the P-Q intervals were not affected by verapamil. The mechanism of action in angina pectoris is discussed, but it is concluded that it is still not possible to explain it. Twelve Danish medical departments took part in the trial.
