RESUMO
A case with a complex chromosome abnormality with a t(2;2)(p23;q23) in CD30+/Ki-1+ anaplastic large cell lymphoma (ALCL) is described. This chromosome aberration has not been reported previously in neoplastic diseases and was associated with T-cell phenotype and involvement of the nasopharynx by the tumour.
Assuntos
Cromossomos Humanos Par 2 , Linfoma Anaplásico de Células Grandes/genética , Translocação Genética , Idoso , Humanos , Cariotipagem , MasculinoRESUMO
A case of a pure heterologous sarcoma of mixed type (pleomorphic rhabdomyosarcoma and chondrosarcoma) localized in the uterine corpus of a 75-year-old woman is presented. The tumor was investigated by routine morphologic methods, immunohistochemically, and on ultrastructural level. The histogenesis of the tumor and the problems of differential diagnosis with other tumors of the same localization are under discussion.
Assuntos
Condrossarcoma/patologia , Rabdomiossarcoma/patologia , Neoplasias Uterinas/patologia , Idoso , Condrossarcoma/química , Condrossarcoma/cirurgia , Desmina/análise , Feminino , Humanos , Imuno-Histoquímica , Miosinas/análise , Pós-Menopausa , Rabdomiossarcoma/química , Rabdomiossarcoma/cirurgia , Neoplasias Uterinas/química , Neoplasias Uterinas/cirurgiaRESUMO
The malignant melanomas of the gastrointestinal tract, especially their achromatic variants, are rare primary tumors, causing certain diagnostic problems. We report three cases of primary malignant melanomas (two of them being achromatic) of the small intestine and anal canal in patients in their fifth decade of life. For precise diagnosis, a parallel investigation was conducted using histology, histochemistry, immunohistochemistry, and electron microscopy. Consideration is also given to the mechanism of these tumors.
