[Regulation of the blood-brain barrier permeability in suppurative-inflammatory diseases of the maxillofacial area]. / Reguliatsiia pronitsaemosti gematoéntsefalicheskogo bar'era pri gnoino-vospalitel'nykh zabolevaniiakh cheliustno-litsevoi oblasti.

Hematoencephalic barrier (HEB) permeability was studied in 78 rabbits. HEB permeability for 32P was examined in animals with phlegmons on the posterior paws and on the maxillofacial area; HEB permeability was sharply increased in the latter group animals. Central cholinolytics and antioxidants were used to normalize this parameter in the rabbits with maxillofacial phlegmons.

[Immunological aspects of the effect of inflammatory diseases of the maxillofacial area on the brain]. / Immunologicheskie aspekty vliianiia vospalitel'nykh zabolevanii cheliustno-litsevoi oblasti na golovnoi mozg.

Indirect hemagglutination was used to detect the blood serum antibrain antibodies in 472 patients with inflammatory maxillofacial diseases. Long-term follow-up was performed in 109 of the patients. High titres of antibrain antibodies were found. These were most pronounced in patients with concomitant odontogenic phlegmons. The disease severity correlated with the antibrain antibodies titers. The bodily disorders in severe odontogenic infection are accounted for by an "overload syndrome" due to the inflammatory focus influence on the brain and, subsequently, vicious circle formation involving facial inflammation and the brain as the organ of central homeostatic regulation.