Assuntos
Eritema Nodoso/diagnóstico , Adulto , Diagnóstico Diferencial , Eritema Nodoso/patologia , Feminino , Humanos , Perna (Membro)RESUMO
We report a case of onychomycosis caused by Candida tropicalis in a 107-day-old infant.
Assuntos
Candida tropicalis/isolamento & purificação , Recém-Nascido Prematuro , Onicomicose/diagnóstico , Diagnóstico Diferencial , Feminino , Dermatoses da Mão/diagnóstico , Dermatoses da Mão/patologia , Humanos , Recém-Nascido , Onicomicose/patologiaRESUMO
Photochemotherapy using psoralen and ultraviolet (UV)A irradiation (PUVA) is a useful treatment method for vitiligo. However, long-term PUVA therapy may cause several adverse effects including skin cancer, especially squamous cell carcinoma (SCC). We describe a case of SCC in vitiligo lesion after long-term PUVA therapy.
Assuntos
Carcinoma de Células Escamosas/etiologia , Terapia PUVA/efeitos adversos , Pênis/patologia , Neoplasias Cutâneas/etiologia , Vitiligo/tratamento farmacológico , Adulto , Biópsia por Agulha , Carcinoma de Células Escamosas/patologia , Seguimentos , Humanos , Imuno-Histoquímica , Assistência de Longa Duração , Masculino , Terapia PUVA/métodos , Medição de Risco , Neoplasias Cutâneas/patologia , Vitiligo/diagnósticoRESUMO
Leishmaniasis is one of the important tropical diseases in the world. Although it is not prevalent in Korea, imported cases have been recorded. The karyotype of Leishmania sp. has been observed to be variable by localities or by strains, but the karyotype of a strain is known to be stable. This study was performed to observe if the karyotype of a Leishmania sp. would be changed under some stressful conditions. The karyotype, analyzed by pulsed field gradient gel electrophoresis, was not grossly changed by heat shock, chemotherapeutics, UV illumination, and gamma irradiation. Radiation destroyed the chromosomes mechanically, but subcultured organisms after irradiation showed unaffected karyotype. The present findings suggest that the karyotype of a Leishmania strain is so stable that it is not altered by temporary stimulation with heat, drugs, and radiation.