1.
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
; 29(4): 526-529, 2017 Jul 24.
Artigo
em Chinês
| MEDLINE
| ID: mdl-29508600
RESUMO
ATP (Adenosine triphosphate) is an important endogenous damage - associated molecular pattern (DAMP). P2X7R is an ATP-gated cation channel. ATP-P2X7R plays a vital role in the pathophysiology of many diseases because P2X7R is distributed on various immune cells. ATP-P2X7R signal transduction pathway has been implicated to participate in the body's immune defense against pathogens. This paper reviews the recent progress regarding ATP-P2X7R and its effects on parasitic diseases.