Identification of Phenotype and Genotype in One Case with Weak D blood group / 中国实验血液学杂志

OBJECTIVE@#To investigate the phenotype and genotype of the weak D blood group in one case of Chinese Han people.@*METHODS@#Phenotype of blood sample was identified with serologic tests; PCR-SBT was applied for the analysis of genotype and RhD zygosity.@*RESULTS@#Both saline and gel card tests demonstrated this case to be dCcee, which was contrary to glass bead card result. Some of the RBC D epitopes were negative.c.1022T>A allele was identified with PCR-SBT and the zygosity analysis showed this case to be D/d.@*CONCLUSION@#RHD*1022 A is more suitable to be categorized as weak partial D other than weak D in a Chinese Han people.

A study on mental health status of secondary school students and its influencing life events / 预防医学

Objective To investigate the mental health status of secondary school students in Wenzhou and to analyze its association with life events.Methods Cluster sampling method was used and Chinese Secondary School Students Mental Health Scale and Adolescence Life Events Scale were adopted to test 3 200 secondary school students.Results A total of 25.62％ students had psychological problems,and 22.50 ％ of them had mild mental problems,and 3.13％ of them had moderate mental problems,but none of them had severer psychological problems.Girls scored higher than boys in depression (P ＜ 0.05).The scores of mental health in senior high school group was higher than that in junior high school group in the total scores of psychological health,average score,poor adaptation,emotional fluctuation,compulsion,interpersonal sensitivity,depression,anxiety,paranoid ideation,psychological imbalance and learning pressure.The middle school students' psychological problems were learning pressure (47.79％),forced (44.12％),mood swings (42.23％),anxiety (33.76％),poor fit (32.21％),and interpersonal sensitivity (30.62％).The middle school students' life events in the assessment of interpersonal relationship was the highest score (5.74 ± 4.25);followed by learning pressure (5.70 ±3.79),punishment (4.63 ±3.67),loss (2.86 ±2.68),health (2.48 ±2.14).Multiple linear regression analysis showed that learning pressure and interpersonal events were the influencing factors of mental health of middle school students,and the influence of learning stress events was greater than that of interpersonal events.Conclusion The pressure of study,forcing problems presented in middle school students in Wenzhou,especially high school students.Pressure of study,interpersonal relationships were the main life events influencing mental health of middle school students in Wenzhou.