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1.
Khirurgiia (Sofiia) ; 60(1): 42-4, 2004.
Artigo em Búlgaro | MEDLINE | ID: mdl-15704750

RESUMO

Polyposis of the colon is a colon cancer predisposition syndrome. Familial adenomatous polyposis (FAP) accounts for 1% of the cases of inherited colorectal cancer (CRC). The National Register of inherited CRC and polyposis of the intestines keeps track of 18 patients from 14 families with FAP. Eight of them have been operated of CRC, on 6 patients preventive colectomy with ileorectal anastomosis has been done and four patients refused surgery. Colectomy has been done due to the malignant development also on a female patient with difused juvenile polyposis with adenomatosis. Of three patients under surveillance with the Peutz-Jeghers syndrome, surgery has been done on one female patient with ileus and bleeding large polyps.


Assuntos
Polipose Adenomatosa do Colo , Neoplasias Colorretais , Polipose Adenomatosa do Colo/complicações , Polipose Adenomatosa do Colo/epidemiologia , Polipose Adenomatosa do Colo/cirurgia , Bulgária/epidemiologia , Colectomia , Neoplasias Colorretais/complicações , Neoplasias Colorretais/epidemiologia , Neoplasias Colorretais/genética , Neoplasias Colorretais/cirurgia , Feminino , Síndrome de Gardner/complicações , Síndrome de Gardner/genética , Síndrome de Gardner/cirurgia , Predisposição Genética para Doença , Humanos , Síndrome de Peutz-Jeghers/complicações , Síndrome de Peutz-Jeghers/genética , Síndrome de Peutz-Jeghers/cirurgia , Pólipos/cirurgia , Sistema de Registros/estatística & dados numéricos
3.
Eur J Gastroenterol Hepatol ; 8(9): 911-4, 1996 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-8889460

RESUMO

OBJECTIVE: To propose two modified urease tests for the detection of Helicobacter pylori in gastric biopsy specimens. PATIENTS AND METHODS: The presence of H. pylori infection was determined in 237 patients undergoing upper gastrointestinal endoscopy. Three media were used for the urease tests: Christensen's 2% urea broth and two urea agar media, modified by increasing the concentration of urea (to 4% and 10%) and phenol red and omitting the nutrients. RESULTS: The modified tests had good sensitivity (> 78%), specificity (96%) and accuracy (> or = 86%) at 2 h using small amounts (15%) of biopsy homogenates. They were statistically more sensitive and accurate than Christensen's broth. CONCLUSION: Both the modified 4% and 10% urea agar tests are simple, sensitive and specific and can be performed with small amounts of sample.


Assuntos
Gastroenteropatias/microbiologia , Infecções por Helicobacter/diagnóstico , Helicobacter pylori/isolamento & purificação , Urease/análise , Técnicas Bacteriológicas , Biópsia , Gastroenteropatias/patologia , Helicobacter pylori/enzimologia , Técnicas Histológicas , Humanos , Valor Preditivo dos Testes , Sensibilidade e Especificidade
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