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Allerg Immunol (Paris) ; 28(9): 308-10, 1996 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-8986246

RESUMO

A double blind study was made on a group of 35 children, 8 of whom were allergic to Grass and 27 allergic to Pteronyssinus and Farinae Dermatophagoides. We verified the efficacy and tolerability of a new immunotherapy called E.P.D. (Enzyme Potentiated Desensitization). This particular immunotherapy consists in an intradermal injection of a mix made up of an allergic solution at extremely low doses and an enzyme, beta-glucuronidase. The vaccine is administered once a year, two weeks before pollen peaks for children with seasonal allergies and two times a year, in February and November, for children with non-seasonal allergies (Dermatophagoides). The results, statistically analyzed on the basis of a symptoms score, showed good clinical efficacy in patients affected by both seasonal and non-seasonal allergies. Due to the clinical effectiveness, easy administration and excellent tolerability of the immunotherapy, E.P.D. is particularly suited for treating or reducing allergic symptoms in allergic children.


Assuntos
Alérgenos/uso terapêutico , Asma/terapia , Conjuntivite Alérgica/terapia , Dessensibilização Imunológica/métodos , Rinite Alérgica Perene/terapia , Rinite Alérgica Sazonal/terapia , Adolescente , Alérgenos/administração & dosagem , Animais , Asma/etiologia , Criança , Pré-Escolar , Conjuntivite Alérgica/etiologia , Método Duplo-Cego , Esquema de Medicação , Feminino , Glucuronidase/administração & dosagem , Humanos , Injeções Intradérmicas , Masculino , Ácaros/imunologia , Pólen/imunologia , Rinite Alérgica Perene/etiologia , Rinite Alérgica Sazonal/etiologia , Segurança , Estações do Ano , Resultado do Tratamento
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