RESUMO
PURPOSE: The goal of this study was to investigate the radiation dose and diagnostic efficacy of cardiac computed tomography angiography (CCTA) using prospective ECG-gated high-pitch dual-source computed tomography (DSCT) in the diagnosis of congenital cardiovascular abnormalities in pediatric population. MATERIALS AND METHODS: One hundred five pediatric patients who were clinically diagnosed with congenital heart disease with suspected extracardiac vascular abnormalities were included in the study. All CCTAs were performed on a 128×2-section DSCT scanner. CCTA findings were compared with surgical and/or conventional cardiac angiography findings. Dose-length product (DLP) and effective doses (ED) were calculated for each patient. Patients were divided into 4 groups by age, and ED and DLP values were compared among groups. The image quality was evaluated using a five-point scale. RESULTS: CCTA showed 173 abnormalities in 105 patients. There were 2 patients with false positive and 3 with false negative findings. The sensitivity and specificity of CCTA were 98.3% and 99.9%, respectively. The positive predictive value and negative predictive value of CCT were 98.9% and 99.9%, respectively. The average DLP and ED values were 15.6±9.6 (SD) mGy.cm and 0.34±0.10 (SD) mSv, respectively. The mean image quality score was 4.8±0.5 (SD) in all patients. The inter-observer agreement for the image quality scores was good (κ=0.80). CONCLUSION: CCTA is an excellent imaging modality for evaluation of cardiovascular abnormalities and provides excellent image quality with very low radiation exposure when low-dose prospective ECG-triggered high-pitch DSCT is used.
Assuntos
Anormalidades Múltiplas/diagnóstico por imagem , Técnicas de Imagem de Sincronização Cardíaca/métodos , Anormalidades Cardiovasculares/diagnóstico por imagem , Angiografia por Tomografia Computadorizada/métodos , Angiografia Coronária/métodos , Cardiopatias Congênitas/diagnóstico por imagem , Processamento de Imagem Assistida por Computador/métodos , Adolescente , Criança , Pré-Escolar , Humanos , Lactente , Recém-Nascido , Imagens de Fantasmas , Estudos Prospectivos , Doses de Radiação , Sensibilidade e EspecificidadeRESUMO
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Assuntos
Humanos , Masculino , Feminino , Criança , Aneurisma Coronário/metabolismo , Aneurisma Coronário/patologia , Síndrome de Linfonodos Mucocutâneos/diagnóstico , Tomografia Computadorizada por Raios X/métodos , Tuberculose dos Linfonodos/diagnóstico , Conjuntivite/metabolismo , Ultrassonografia/métodos , Aneurisma Coronário/complicações , Aneurisma Coronário , Síndrome de Linfonodos Mucocutâneos/complicações , Tomografia Computadorizada por Raios X/instrumentação , Tuberculose dos Linfonodos/complicações , Conjuntivite/patologia , Ultrassonografia/instrumentaçãoAssuntos
Linfócitos B , Transtornos Cromossômicos/complicações , Transtornos Cromossômicos/diagnóstico , Cardiopatias Congênitas/complicações , Anormalidades Múltiplas/diagnóstico , Anormalidades Múltiplas/genética , Deleção Cromossômica , Transtornos Cromossômicos/genética , Cromossomos Humanos Par 18/genética , Feminino , Cardiopatias Congênitas/genética , Humanos , Recém-NascidoRESUMO
Seckel syndrome is an autosomal recessive disease presenting with marked growth retardation, microcephalic dwarfism, some facial and skeletal abnormalities. Tricuspid atresia is a rare and life threatening cyanotic congenital heart diseases, with an incidence of 1% to 3%. It is feature of the anatomically normally related great arteries with a large ventricular septum defect and stenosis of right ventricular outflow tract. Tricuspid atresia has never been reported in patients with Seckel syndrome. Here we report a 15-day-old girl baby diagnosed as having Seckel syndrome with tricuspid atresia.
