Investigation on the effect of collagen and vitamins on biomimetic hydroxyapatite coating formation on titanium surfaces.

This study uses an in vitro experimental approach to investigate the roles of collagen and vitamins in regulating the deposition of hydroxyapatite layer on the pure titanium surface. Titanium implants were coated with a hydroxyapatite layer under biomimetic conditions by using a supersaturated calcification solution (SCS), modified by adding vitamins A and D3, and collagen. The hydroxyapatite deposits on titanium were investigated by means of scanning electron microscopy (SEM) coupled with X-ray analysis (EDX), X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD) and Fourier transformed infrared (FTIR) spectroscopy. The results obtained have shown that hydroxyapatite coatings were produced in vitro under vitamins and collagen influence.

SEM and EDX studies of bioactive hydroxyapatite coatings on titanium implants.

This work presents a study on an alternative coating method based on biomimetic techniques which are designed to form a crystalline hydroxyapatite layer very similar to the process corresponding to the formation of natural bone. The HA formation on the surface of titanium alloy pretreated with NaOH solution is investigated. Two types of solutions such as supersaturated calcification solution (SCS) and modified SCS (M-SCS) were used to investigate bone-like apatite formation on alkali-treated titanium. The hydroxyapatite deposits are investigated by means of scanning electron microscopy (SEM) and energy dispersive X-ray analysis (EDX). The data suggest that the method utilized in this work can be successfully applied to obtain deposition of uniform coatings of crystalline hydroxyapatite on titanium substrates.

The use of a Computer Aided Design (CAD) environment in 3D reconstruction of anatomic surfaces.

Paper presents an evaluation and comparison of two different types of software for generating a 3D model from medical imaging data: first, a dedicated 3D reconstruction Mimics interface, by Materialise and second, an engineering CAD (a Solid Works and AutoCAD) interface. Advantages and limitations of both software types are outlined and there some observations for 3D reconstruction of anatomic surfaces are presented.