[Usher's syndrome]. / Sindrom Usher tip II --caz clinic.

PURPOSE: to show the manner of diagnose of this syndrome and to evaluate the possibilities of treatment MATERIAL AND METHOD--there are shown: --ophthalmological and ENT clinical examination --visual field test--adaptometry--audiometry --impedance--auditive evoked potentials--cataract extraction (phacoemulsification). RESULTS: After cataract extraction the visual acuity increase. CONCLUSIONS: For the diagnosis we need both the diagnosis of retinitis pigmentosa and neurosensorial deafness. For the certainty of the diagnosis genetic tests are required. The treatment of associate ocular pathology may increase the visual status.

[Histopathological assessment of corneal preservation]. / Evaluarea histopatologica a posibilitatilor de conservare a corneei.

PURPOSE: To show corneal changes after corneal preservation. MATERIAL AND METHOD: There was studied 10 pig corneas: a fresh cornea; two corneas stored in wet chamber at 4 degrees C, 24 and 48 hours; seven corneas stored in Inosol at 31 degrees C, 24 hours, 7, 10, 14, 18, 20 and 22 days. RESULTS: We obtained images of every cornea; we followed epithelial, stromal and endothelial changes. CONCLUSIONS: 1. During corneal preservation there are progressive histological changes, early in epithelium and stroma, later at endothelial level. 2. The safe preservation period in wet chamber at 4 degrees C is 24 hours; the changes found after 48 hours are irreversibile. 3. The safe preservation period in Inosol at 31 degrees C is 14 days.

[Corneal preservation at 31 degrees C--experimental study]. / Conservarea corneei la 31 degrees C--studiu experimental.

PURPOSE: To study the cornea, specially the corneal endothelium in preservation media for different periods of time, trying to assess the best period of preservation. To evaluate the endothelial cell loss during preservation, trying to assess the endothelial cell minimum density for a cornea able to be preserved. MATERIAL AND METHODS: We studied 7 human corneas and 15 pig corneas. We used the inverted specular microscope, Axiovert 100. We used the soft KS 400 for image processing. We used to preservation medium: Inosol-like. We made an initial examination, then after 1,4,7,10 and 14 days. RESULTS: In human corneas the mean cell loss(%) was 4.1% from initial cell density after 4 days of preservation, 14.7% after 7 days, 18.6% after 10 days and 23.4% after 14 days. In pig corneas the mean cell loss (%) was 2.3% from initial cell density after 4 days of preservation, 8.8% after 7 days, 14.9% after 10 days and 23% after 14 days. CONCLUSIONS: The best period of preservation in Inosol-like medium is 7-10 days. This period may be extended to 14 days. During preservation there is an endothelial cell loss which after 14 days is about 23% from initial endothelial cell density (about 550 cell/mm2). The minimum initial endothelial cell density for a cornea to be able to be preserved is 2400 cell/mm2.

[Corneal preservation at 4 degrees C--experimental study]. / Conservarea corneei la 4 degrees C studiu experimental.

AIM OF STUDY: To evaluate the 4 degrees C method of corneal preservation (in moist chamber or in preservation media To determine the duration of prevention. MATERIAL AND METHOD: Preservation in moist chamber at 4 degrees C, group of 10 pig eyes. Preservation: the entire globe at 4 degrees C examination: direct specular microscopy with a Tomey device, daily, for 4 days. Preservation in Likorol DX at 4 degrees C, group: 20 pig eyes Preservation: Likorol DX medium, we change the medium after 7 days. examinations: inverse specular microscopy, with a Zeiss device, after 1, 4, 7, 10 and 14 days. RESULTS: Preservation in moist chamber at 4 degrees C. The average endothelial cell loss was 13.2% after a day of preservation and 27.1% after 2 days. Preservation in Likorol DX at 4 degrees C The average endothelial cell loss was 2.8% after a day of preservation, 13.8% after 7 days and 22.6% after 10 days. CONCLUSIONS: The corneal preservation in moist chamber at 4 degrees C is a useful method; it is safe to preserve the globe only for 24 hours. It is safe to preserve corneas in Likorol DX medium for 7 days, there is an endothelial cell loss, about 13.8%.

[Blue-yellow full threshold automated perimetry in glaucoma diagnosis]. / Importanta diagnostica în glaucom a perimetriei computerizate Full Threshold Albastru-Galben.

PURPOSE: To compare White & White and Blue-Yellow Full Threshold automated perimetry. MATERIAL AND METHOD: Group of 37 patients; we used a Humphrey Zeiss automated perimeter. RESULTS: We obtained 49% abnormal white & white visual fields and 62% abnormal blue yellow fields. CONCLUSIONS: Blue Yellow perimetry has higher sensibility than white & white perimetry. We can detect earlier with this test the glaucoma defects.

[Post-inflammatory glaucoma--methods of treatment]. / Glaucomul postinflamator--particularitati de tratament pornind de la un caz clinic.

We show the mechanisms of postinflammatory secondary glaucoma and the possibilities of treatment of this, all of this concerning to an individual case. We evaluate the benefits and risks for every kind of therapeutical approach and we show our choice.