Assuntos
Exantema/etiologia , Cefaleia/etiologia , Tifo Endêmico Transmitido por Pulgas/diagnóstico , Animais , Antibacterianos/uso terapêutico , Contagem de Células Sanguíneas , Diagnóstico Diferencial , Vetores de Doenças , Doxiciclina/uso terapêutico , Febre/etiologia , Humanos , Masculino , Rickettsia typhi , Texas , Transaminases/sangue , Viagem , Tifo Endêmico Transmitido por Pulgas/complicações , Tifo Endêmico Transmitido por Pulgas/tratamento farmacológico , Tifo Endêmico Transmitido por Pulgas/transmissão , Adulto JovemRESUMO
Illicit drug use can result in a wide range of medical complications. As the availability, synthesis, and popularity of illicit drugs evolve over time, new syndromes associated with their use may mimic infections. Some of these symptoms are anticipated drug effects, and others are complications of adulterants mixed with drugs or complications from the method of using drugs. Some illicit drugs are associated with rare infections, which are difficult to diagnosis with standard microbiological techniques. The goal of this review is to orient a wide range of clinicians-including general practitioners, emergency medicine providers, and infectious diseases specialists-to complications of illicit drug use that may be underrecognized. Improving awareness of infectious and noninfectious complications of illicit drug can expedite diagnosis and medical treatment of persons who use drugs and facilitate targeted harm reduction counseling to prevent future complications.
Assuntos
Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos/epidemiologia , Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos/patologia , Drogas Ilícitas/efeitos adversos , Abuso de Substâncias por Via Intravenosa/complicações , Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos/diagnóstico , HumanosAssuntos
Síndrome Pulmonar por Hantavirus/diagnóstico , Bloqueio de Ramo/diagnóstico , Diagnóstico Diferencial , Dispneia/etiologia , Síndrome Pulmonar por Hantavirus/complicações , Testes Hematológicos , Humanos , Pulmão/diagnóstico por imagem , Masculino , Pessoa de Meia-Idade , Radiografia , Febre Maculosa das Montanhas Rochosas/diagnóstico , ViagemRESUMO
Prevention is the best method for avoiding potentially serious complications of Lyme and other tick-borne diseases. In this article, we discuss preventative measures that can be used by individuals or communities. Among the topics discussed are personal protective measures, tick reduction, reservoir reduction, and vaccination. Additionally, new preventative measures that are in development-including new Lyme disease vaccines, antitick vaccines, and reservoir-targeted vaccination-are discussed.
Assuntos
Vacinas contra Doença de Lyme , Doença de Lyme/prevenção & controle , Controle de Ácaros e Carrapatos/métodos , Doenças Transmitidas por Carrapatos/prevenção & controle , Carrapatos/crescimento & desenvolvimento , Animais , Reservatórios de Doenças/veterinária , Humanos , Roupa de ProteçãoRESUMO
INTRODUCTION: Diabetic ketoacidosis (DKA) continues to be a medical emergency, in part because of a rare and devastating complication associated with its treatment, cerebral edema. In children, cerebral edema is the principal cause of mortality, but clinically significant cerebral edema in adults is rare. METHODS AND RESULTS: We report the case of a 27-year-old male (not previously known to be diabetic) who presented with a first episode of DKA complicated by the development of fatal cerebral edema despite medical treatment. CONCLUSION: The pathophysiological mechanisms for cerebral edema associated with DKA occurring in children and adults are believed to be similar and are discussed in this report. However, patients who develop cerebral edema may deteriorate rapidly, and experience with successful treatment has been limited.