The role of residual renal function on potassium intake and excretion in patients on peritoneal dialysis.

BACKGROUND: Patients on chronic dialysis are at increased risk of developing disorders in potassium balance. The preservation of residual renal function (RRF), frequently observed in patients on peritoneal dialysis (PD), may contribute to better control of serum potassium. This study aimed to investigate the role residual renal function on potassium intake and excretion in PD patients. METHODS: In this cross-sectional study, dietary potassium was evaluated by the 3-day food record. Potassium concentration was determined in serum, 24 h dialysate, stool ample, and 24 h urine of patients with diuresis > 200 mL/day, who were considered non-anuric. RESULTS: Fifty-two patients, 50% men, 52.6 ± 14.0 years, and PD vintage 19.5 [7.0-44.2] months, were enrolled. Compared to the anuric group (n = 17, 33%), the non-anuric group (n = 35, 67%) had lower dialysate potassium excretion (24.8 ± 5.3 vs 30.9 ± 5.9 mEq/d; p = 0.001), higher total potassium intake (44.5 ± 16.7 vs 35.1 ± 8.1 mEq/d; p = 0.009) and potassium intake from fruit (6.2 [2.4-14.7] vs 2.9 [0.0-6.0]mEq/d; p = 0.018), and no difference in serum potassium (4.8 ± 0.6 vs 4.8 ± 0.9 mEq/L; p = 0.799) and fecal potassium (2.2 ± 0.5 vs 2.1 ± 0.7 mEq/L; p = 0.712). In non-anuric patients, potassium intake correlated directly with urinary potassium (r = 0.40; p = 0.017), but not with serum, dialysate, or fecal potassium. In the anuric group, potassium intake tended to correlate positively with serum potassium (r = 0.48; p = 0.051) and there was no correlation with dialysate or fecal potassium. CONCLUSION: The presence of residual renal function constitutes an important factor in the excretion of potassium, which may allow the adoption of a less-restrictive diet.

Development and Validation of a Food Frequency Questionnaire to Assess Potassium Intake of Patients on Hemodialysis.

OBJECTIVE: To develop and to validate a food frequency questionnaire (FFQ) to assess potassium intake of patients on hemodialysis. METHODS: This is a cross-sectional study that included 41 patients in the FFQ development step and 53 patients in the FFQ validation step. In the FFQ development step, the patients completed a 3-day food record (used as a reference method). Total potassium intake and potassium from each food item were calculated. Food items that contributed up to 90% of the total potassium intake were considered to be included in the FFQ food list. Then the FFQ was applied in person through the google-forms platform. The result of potassium intake obtained by the FFQ was compared with that obtained by the 3-day food record. RESULTS: A total of 94 patients were included: 53.2% women; age 55.7 ± 15.0 years; 47.9% had diabetes; body mass index 25.0 ± 4.5 kg/m2; and dialysis vintage 34.5 (17.0-68.2) months. Demographic, clinical, and laboratory parameters did not differ between the development and validation groups. From the 255 registered food items, 85 comprised the FFQ. The standardized Cronbach's alpha obtained was 0.71. No difference was found between the potassium intake obtained by the FFQ and by the 3-day food record (1,438.5 ± 659.4 mg/d vs. 1,464.8 ± 529.4 mg/d; P = .753, respectively) with an intraclass correlation coefficient of 0.66 (P = .001). No systematic bias or proportionality bias between the methods was observed in the Bland-Altman graphical analysis. CONCLUSION: The quantitative FFQ presented strong relative validity and may constitute a practical tool in the analysis of potassium intake of patients on hemodialysis.

Diet in Chronic Kidney Disease: an integrated approach to nutritional therapy.

A healthy diet is an essential requirement to promote and preserve health, even in the presence of diseases, such as chronic kidney disease (CKD). In this review, nutritional therapy for CKD will be addressed considering not only the main nutrients such as protein, phosphorus, potassium, and sodium, which require adjustments as a result of changes that accompany the reduction of renal functions, but also the benefits of adopting dietary patterns associated with better outcomes for both preventing and treating CKD. We will also emphasize that these aspects should also be combined with a process of giving new meaning to a healthy diet so that it can be promoted. Finally, we will present the perspective of an integrated approach to the individual with CKD, exploring the importance of considering biological, psychological, social, cultural, and economic aspects. This approach has the potential to contribute to better adherence to treatment, thus improving the patient's quality of life.

Diet in Chronic Kidney Disease: an integrated approach to nutritional therapy

SUMMARY A healthy diet is an essential requirement to promote and preserve health, even in the presence of diseases, such as chronic kidney disease (CKD). In this review, nutritional therapy for CKD will be addressed considering not only the main nutrients such as protein, phosphorus, potassium, and sodium, which require adjustments as a result of changes that accompany the reduction of renal functions, but also the benefits of adopting dietary patterns associated with better outcomes for both preventing and treating CKD. We will also emphasize that these aspects should also be combined with a process of giving new meaning to a healthy diet so that it can be promoted. Finally, we will present the perspective of an integrated approach to the individual with CKD, exploring the importance of considering biological, psychological, social, cultural, and economic aspects. This approach has the potential to contribute to better adherence to treatment, thus improving the patient's quality of life.

RESUMO Uma dieta saudável é essencial para promover e preservar a saúde, mesmo na presença de doenças como a Doença Renal Crônica (DRC). Nesta revisão, a terapia nutricional para pacientes de DRC será abordada levando em conta não só os principais nutrientes que precisam ser ajustados devido às alterações que acompanham a redução das funções renais, tais como proteínas, fósforo, potássio e sódio. Abordaremos também os benefícios da adoção de padrões alimentares associados a desfechos melhores tanto para a prevenção quanto para o tratamento da DRC. Também enfatizaremos que esses aspectos devem ser aliados a um processo de ressignificação do conceito de dieta saudável para que seja possível a sua promoção. Por último, apresentaremos a perspectiva de uma abordagem integrada para o indivíduo com DRC, explorando a importância de considerar aspectos biológicos, psicológicos, sociais, culturais e econômicos. Essa abordagem tem o potencial de contribuir para uma melhor adesão ao tratamento, melhorando assim a qualidade de vida do paciente.

Medidas fonológicas em crianças com transtorno fonológico / Phonological measures in children with phonological disorders

OBJETIVO: Comparar o desempenho de crianças com e sem transtorno fonológico (TF) quanto às habilidades de consciência fonológica (CF), índice de Porcentagem de Consoantes Corretas - Revisada (PCC-R) e Índice de Inconsistência de Fala (IIF), além de correlacionar estes resultados entre si. MÉTODOS: Participaram 36 sujeitos, entre 5 anos e 7 anos de idade, divididos em: Grupo Pesquisa (GP): 18 crianças com TF; e Grupo Controle (GC): 18 crianças em desenvolvimento típico de linguagem. Foi calculado o PCC-R, aplicado o IIF e o Teste de Sensibilidade Fonológica-Visual (TSF-V): aliteração igual (AI), diferente (AD) e total (AT), rima igual (RI), diferente (RD) e total (RT). Os resultados foram analisados estatisticamente. RESULTADOS: Foram encontradas diferenças na comparação dos grupos em todos os índices, com melhores desempenhos no GC. Neste, houve correlação negativa do IIF com todas as habilidades de CF e com o PCC-R, exceto com RI. Em todos os subtestes do TSF-V houve correlações positivas entre si. No GP, foram encontradas correlações positivas entre o PCC-R e as provas de aliteração; não foram encontradas correlações entre IFF e PCC-R, nem com as provas de CF. Houve correlações no TSF-V: AI com AT; AD com AT; AD com RD; RI com RT e RD com RT. CONCLUSÃO: Crianças com TF apresentam pior desempenho; as do GC, na medida em que estabilizam a produção de fala, desenvolvem as habilidades de rima e aliteração. As crianças do GP são mais inconsistentes e parecem desenvolver as habilidades de CF de forma desorganizada.

PURPOSE: To compare and correlate the performance of children with and without phonological disorders (PD) according to phonological awareness (PA) abilities, Percentage of Consonants Correct - Revised (PCC-R) and Speech Inconsistency Index (SII). METHODS: Participants were 36 children with ages between 5 and 7 years divided into: Research Group (RG) - 18 children with PD; and CG - 18 typically developing children. The PCC-R was calculated, and the SII and the Phonological Sensitivity Test - Visual mode (PST-V) were applied. The PST-V consists of six tasks: equal and different alliteration (EA and DA, respectively), total alliteration (TA), equal and different rhyme (ER and DR, respectively), and total rhyme (TR). Results were statistically analyzed. RESULTS: Differences were found between groups in all indexes, with better performances of the CG. In this group there were negative correlations between SII and all PA abilities and between SII and PCC-R, except for the ER. There were positive correlations between all PST-V subtests. On the RG, positive correlations were observed between PCC-R and alliteration abilities; no correlations were found between SII and PCC-R nor between SII and PA subtests. There were correlations between PST-V abilities: EA and TA; DA and TA; DA and DR; ER and TR; DR and TR. CONCLUSION: Children with PD had worse performances. CG children develop rhyme and alliteration abilities as they stabilize their speech production. RG children are more inconsistent and tend to develop PA abilities in a more disorganized manner.