[Peritoneostomy with latex coated polypropylene: experimental study in rats]. / Peritoniostomia com polipropileno revestido por látex: estudo experimental em ratos.

PURPOSE: To evaluate if latex coated polypropylene mesh leads to less adhesions formation. METHODS: 90 rats were distributed in three groups. Group I (control) was submitted to median laparotomy and posterior synthesis; Group II (polypropylene) was submitted to a segment resection of the abdominal wall, and the defect was corrected with a polypropylene mesh; Group III using the new material (latex coated polypropylene). After 45 days the euthanasia procedure was done and the adhesions were evaluated in 2 ways: 1) classification in a grading system; 2) evaluation of the adhesion area, which was calculated by resection of the adhesions after dying with Indian blue ink. RESULTS: The classification in a grading system showed that Group III animals had less adhesions formation (P<0.05), but the evaluation of the adhesion area did not show any difference (P>0.05). The severe complications (fistula, evisceration and obstruction), which were lethal, were not reduced by the latex coated material. CONCLUSION: Latex coated polypropylene causes fewer adhesion formations than polypropylene alone, although it does not diminish the severe early complications.

Peritoneostomy with latex coated polypropylene: experimental study in rats

PURPOSE: To evaluate if latex coated polypropylene mesh leads to less adhesions formation. METHODS: 90 rats were distributed in three groups. Group I (control) was submitted to median laparotomy and posterior synthesis; Group II (polypropylene) was submitted to a segment resection of the abdominal wall, and the defect was corrected with a polypropylene mesh; Group III using the new material (latex coated polypropylene). After 45 days the euthanasia procedure was done and the adhesions were evaluated in 2 ways: 1) classification in a grading system; 2) evaluation of the adhesion area, which was calculated by resection of the adhesions after dying with Indian blue ink. RESULTS: The classification in a grading system showed that Group III animals had less adhesions formation (P<0.05), but the evaluation of the adhesion area did not show any difference (P>0.05). The severe complications (fistula, evisceration and obstruction), which were lethal, were not reduced by the latex coated material. CONCLUSION: Latex coated polypropylene causes fewer adhesion formations than polypropylene alone, although it does not diminish the severe early complications.

OBJETIVO: Avaliar se o revestimento da tela de polipropileno com látex leva a menor formação de aderências. MÉTODOS: Foram utilizados 90 ratos, distribuídos em três grupos de 30: grupo I (controle) animais submetidos a laparotomia mediana e posterior síntese; grupo II (polipropileno) ressecção de segmento da parede abdominal e síntese com tela de polipropileno; grupo III, (polipropileno revestido por látex). Eutanásia foi realizada após 45 dias e as aderências avaliadas sob duas formas: 1) classificação em graus; 2) avaliação da área aderida, calculada corando-se o segmento da parede contendo as aderências que posteriormente foram ressecadas produzindo uma região clara em contraste com o restante da peça, corada. RESULTADOS: Na avaliação por meio de graus, o grupo III apresentou menor formação de aderências (p<0,05), mas quanto a avaliação da área aderida não houve diferença (p>0,05). As complicações graves não foram reduzidas pelo revestimento por látex (p>0,05). CONCLUSÃO: O revestimento da tela de polipropileno por látex leva a menor formação de aderências, porém não diminui as complicações graves precoces.