Failure to feed patients with anorexia nervosa and other perils and perplexities in the medical care of eating disorder patients.

A 28 year old woman with anorexia nervosa was sent to an emergency room by her gastroenterologist for weakness and nausea following placement of a percutaneous endoscopic gastrostomy (PEG) tube, with a plan for admission to the hospital. She spent 2 days in the emergency room without receiving any nutrition, and was discharged home after being told that her laboratory tests and x-rays were normal. The following day, her gastroenterologist reviewed the x-rays and determined that she had a bowel obstruction, at which point she was admitted to the hospital, weighing 2 kg less than on her initial visit. A 26 year old woman with anorexia nervosa was prematurely discharged from a residential facility with a Dobhoff feeding tube in her small intestine. She developed dizziness and weakness and was admitted to the hospital, but did not receive any feeding during the 6 days she was there, despite documented blood sugars in the 30s. Apparently an early order for tube feeding was cancelled, for unclear reasons. Two days after discharge, she again developed weakness and returned to the emergency room with a letter from her physician stating that she required medical supervision for the initiation of feeding. However, she was discharged from the emergency room within hours, only to be re-admitted to the hospital the next day.

Psychopharmacologic treatment of obesity and eating disorders in children and adolescents.

This review discusses the evidence base for medications that are currently used for obesity and eating disorders, including their Food and Drug Administration approval status by disorder and age group, contraindications, and major adverse effects. Investigational agents currently being considered, issues related to psychiatric and medical comorbidity, limitations of pharmacologic strategies, and recommendations for treatment are also addressed.