Imposter phenomenon: recognising and addressing it among nurses.

Imposter phenomenon is described as persistently doubting one's accomplishments, leading to an internalised fear of being exposed as a 'fraud'. This article identifies the nature and prevalence of imposter phenomenon among nursing students, newly registered nurses and senior nurses. It also explores the effects of this phenomenon for nurses and healthcare organisations, including its potential association with burnout, suboptimal performance and a lack of career development. Evidence suggests that addressing imposter phenomenon is not something individuals can accomplish by themselves, but that it requires system-level interventions from healthcare organisations and higher education institutions. This could raise awareness, promote recognition and improve resources and training to mitigate the detrimental effects of this phenomenon on healthcare provision.

Pain and disability were related to Y-balance test but not with proprioception acuity and single-leg triple-hop test in patients with patellofemoral pain: A cross-sectional study.

INTRODUCTION: Patellofemoral pain is a common complaint between physically active subjects. Patients with patellofemoral pain present limitations to performing daily activities. Pain could alter proprioceptive acuity and lead to movement impairment. The aim of this study was to investigate the relationship of pain and disability with proprioception acuity and physical performance in patients with patellofemoral pain. METHODS: Forty-eight patients with patellofemoral pain [age 31.15 (5.91) years; 30 (62.50%) males] were recruited. Data collected included pain intensity, pain duration, disability, joint position sense (JPS) test at 20° and 60° of knee flexion, and physical performance tests (Single-Leg Triple-Hop Test and Y- Balance Test). Spearman's rank correlation coefficient (rs) and 95% confidence intervals (CI) were computed to assess the relationship between the variables. RESULTS: Pain intensity was correlated with Y-Balance Test posteromedial component (rs = -0.32, 95%CI = -0.55 to -0.03, p = 0.029) and the composite score (rs = -0.35, 95%CI = -0.58, -0.07, p = 0.015). Pain duration was correlated with Y-Balance Test posterolateral component (rs = -0.23, 95% CI = -0.53 to -0.01, p = 0.047). Disability was correlated with Y-Balance Test posteromedial component (rs = 0.41, 95% CI = 0.14 to 0.62, p = 0.004). Pain and disability were not correlated with JPS and the Single-Leg Triple-Hop Test. CONCLUSION: Pain and disability were related to Y-Balance Test but not to proprioceptive acuity and Single-Leg Triple-Hop Test in patients with patellofemoral pain.

Estratégias cooperativas para melhorar a cobertura vacinal em crianças no estado de Minas Gerais, Brasil / Cooperative strategies to improve vaccination coverage in children in the state of Minas Gerais, Brazil / Estrategias cooperativas para mejorar la cobertura de vacunación infantil en el estado de Minas Gerais (Brasil)

Objetivo: relatar a experiência das oficinas de uma pesquisa-ação do tipo intervenção elaborada para aumento da cobertura vacinal de crianças em municípios do estado de Minas Gerais. Método: relato de experiência sobre a metodologia empregada nas oficinas organizadas com objetivo de aumentar a cobertura vacinal no estado de Minas Gerais, Brasil. As oficinas foram compostas em quatro etapas: momento motivacional, núcleo contextual, núcleo integrador/planejamento e núcleo integrador/resultados. Resultados: As oficinas mostraram-se potentes na sensibilização e na indução da discussão dos indicadores de cobertura vacinal, evidenciando, inconsistências entre o Sistema de Informação do Programa Nacional de Imunizações e os registros internos dos municípios. Para além dos indicadores, as oficinas, permitiram troca de experiências entre os representantes municipais, discussão de recursos financeiros, estruturação de salas de vacina, aquisição de veículos, contratação de profissionais, entre outros. Considerações Finais: As oficinas mostram-se capaz de evidenciar a realidade dos municípios, para além do reconhecimento das necessidades para melhoria dos processos de imunização, mas também no desenvolvimento de estratégias, capazes de promover aumento das coberturas vacinais.

Objective: to report the experience of workshops of an action research designed to increase vaccination coverage of children in municipalities of the state of Minas Gerais. Method: experience report on the methodology used in the workshops organized to increase vaccination coverage in the state of Minas Gerais, Brazil. The workshops were composed in four stages: motivational moment, contextual core, integrative core/planning and integrative core/results. Results: The workshops proved powerful in raising awareness and inducing discussion of vaccination coverage indicators, evidencing, inconsistencies between the National Immunization Program Information System and the internal records of the municipalities. In addition to the indicators, the workshops allowed the exchange of experiences among municipal representatives, discussion of financial resources, structuring of vaccine rooms, acquisition of vehicles, hiring of professionals, among others. Final Considerations: The workshops are able to highlight the reality of the municipalities, in addition to recognizing the needs for improvement of immunization processes, but also in developing strategies to promote increased vaccination coverage.

Objetivo: relatar la experiencia de los talleres de una investigación-acción diseñada para aumentar la cobertura de vacunación infantil en municipios del estado de Minas Gerais. Método: informe de experiencia sobre la metodología utilizada en los talleres organizados para aumentar la cobertura de vacunación en el estado de Minas Gerais, Brasil. Los talleres constaron de cuatro etapas: momento motivacional, núcleo contextual, núcleo integrador/planificación y núcleo integrador/resultados. Resultados: Los talleres demostraron ser potentes para sensibilizar e inducir la discusión de los indicadores de cobertura de vacunación, evidenciando, inconsistencias entre el Sistema de Información del Programa Nacional de Inmunizaciones y los registros internos de los municipios. Además de los indicadores, los talleres permitieron el intercambio de experiencias entre representantes municipales, discusión de recursos financieros, estructuración de salas de vacunas, adquisición de vehículos, contratación de profesionales, entre otros. Consideraciones Finales: Los talleres se mostraron capaces de evidenciar la realidad de los municipios, más allá del reconocimiento de las necesidades de mejora de los procesos de inmunización, pero también en el desarrollo de estrategias, capaces de promover el aumento de la cobertura de vacunación.

The effects of exercise training on autonomic and hemodynamic responses to muscle metaboreflex in people living with HIV/AIDS: A randomized clinical trial protocol.

BACKGROUND: People living with HIV (PLHIV) present impaired muscle metaboreflex, which may lead to exercise intolerance and increased cardiovascular risk. The muscle metaboreflex adaptations to exercise training in these patients are unknown. The present study aims to investigate the effects of a supervised multimodal exercise training on hemodynamic and autonomic responses to muscle metaboreflex activation in PLHIV. METHODS AND DESIGN: In this randomized clinical trial protocol, 42 PLHIV aged 30-50 years will be randomly assigned at a ratio of 1:1 into an intervention or a control group. The intervention group will perform exercise training (3x/week during 12 weeks) and the control group will remain physically inactive. A reference group composed of 21 HIV-uninfected individuals will be included. Primary outcomes will be blood pressure and heart rate variability indices assessed during resting, mental stress, and activation of muscle metaboreflex by a digital sphygmomanometer and a heart rate monitor; respectively. Mental stress will be induced by the Stroop Color-Word test and muscle metaboreflex will be activated through a post-exercise circulatory arrest (PECA) protocol, being the latter performed without and with the application of a capsaicin-based analgesic balm in the exercised limb. Secondary outcomes will be heart rate, peripheral vascular resistance, stroke volume, cardiac output, blood lactate, anthropometric markers and handgrip maximal voluntary contraction. The intervention and control groups of PLHIV will be evaluated at baseline and after the intervention, while the HIV-uninfected reference group only at baseline. DISCUSSION: The findings of the present study may help to elucidate the muscle metaboreflex adaptations to exercise training in PLHIV. TRIAL REGISTRATION: This study will be performed at University of Rio de Janeiro State following registration at ClinicalTrials.gov as NCT04512456 on August 13, 2020.

Abertura à experiência e preferência em obras de arte figurativas e não figurativas / Opening to experience and preference for figurative and non-figurative works of art / Apertura a la experiencia y preferencia por obras de arte figurativas y no figurativas

A arte não representacional é outra maneira de aludir à arte abstrata, sendo um estilo no qual os objetos não se parecem com aqueles que se apresentam na natureza física concreta. No último século, foram realizadas investigações experimentais sobre estética e personalidade objetivando revelar fatores contribuintes para as diferenças quanto às preferências artísticas. Este estudo explorou as associações entre abertura à experiência e preferência por arte visual. Os participantes completaram a Escala Fatorial de Abertura e classificaram a preferência por quatro imagens diferentes correspondentes à arte representativa e não representativa. A análise estatística dos dados revelou uma correlação positiva entre o fator Fantasia e a apreciação pelas pinturas abstratas (r =.20). Não foi verificada uma correlação estatisticamente significativa entre essa dimensão e a apreciação de pinturas figurativas. Embora esses achados sejam exploratórios, outras medidas mais completas relacionadas às diferenças individuais e preferências artísticas poderão ser utilizadas em novos estudos no Brasil.

Nonrepresentational art is another way to refer to abstract art elating to a style in which objects do not resemble those known in physical nature. In the last hundred years some experimental investigations of aesthetics and personality have been conducted to reveal fundamental factors which contribute to differences in artistic preference. This study explored associations among openness to experience and preference for visual art. Participants completed an Openess Fatorial Scale and provided preference ratings for different paintings corresponding to representational and nonrepresentational art. The statistical analysis of the data showed a positive correlation between the fantasy factor and appreciation for abstract paintings (r =.20). Here was no statistically significant correlation between this same dimension and the appreciation for figurative paintings. Although these findings are somewhat exploratory and more comprehensive measures of individual differences and art preferences could be employed in new studies in Brazil.

El arte no representacional es otra forma de referirse al arte abstracto que se adapta a un estilo en el que los objetos no se parecen a los que se conocen en la naturaleza física concrecta. En el siglo se han llevado a cabo investigaciones experimentales sobre estética y personalidad para revelar los factores contribuintes a las diferencias en preferencias artísticas. Los participantes completaron una Escala Fatorial de Abertura a experiencia y otorgaron calificaciones de preferencia para 4 diferentes images correspondientes al arte representativa y no representativa. El análisis estadístico de los datos mostró correlación entre el factor fantasía y y la apreciación de pinturas abstractas (r =.20). No fue verificada una correlación estadísticamente significativa entre esta dimension y la apreciación de las pinturas figurativas. Aunque estos hallazgos son exploratorios y podrían emplear medidas más completas de diferencias individuales y preferencias artísticas en nuevos estudios en Brasil.

Knee proprioceptive function and physical performance of patients with patellofemoral pain: A matched case-control study.

BACKGROUND: Patients with patellofemoral pain (PFP) present pain, functional limitation, and alteration in knee proprioception. PURPOSE: To compare the knee joint position sense and lower extremity functionality between patients with PFP and controls. Secondarily, investigate the relationship between proprioceptive acuity and physical performance. METHODS: This is a matched case-control study including 48 patients with PFP and 48 healthy individuals matched by age, sex, weight, height, and limb dominance. The proprioceptive evaluation was performed using the joint position sense test (absolute error and relative error) and functionality was assessed using the Single-Leg Triple-Hop test and the Y-Balance Test. The groups were compared using the independent student's T-test. Proprioceptive acuity and physical performance correlations were determined by Pearson correlation coefficient. RESULTS: Participants were on average 31 years old and 62.5% were men. There was no statistically difference for absolute and relative angular error between groups. Patients presented lower relative reached distance on the anterior direction of the Y-Balance Test than controls [patients=58.6 (6.6) % versus controls=61.7 (5.9) %, p=.020]. No differences between groups were found for other functional measures. Significant correlation was found between absolute angular error and anterior component at 60° (r=0.225, p=.028) and relative angular error at 60° with the posterolateral component of the Y- Balance Test (r=0.231, p=.024). CONCLUSION: Proprioceptive acuity of patients with PFP was not reduced. The anterior direction of the Y-Balance Test was impaired compared to matched controls. Proprioceptive sense is related to dynamic balance but not to jump ability.

Multicenter Validation of a Deep Learning Detection Algorithm for Focal Cortical Dysplasia.

BACKGROUND AND OBJECTIVE: To test the hypothesis that a multicenter-validated computer deep learning algorithm detects MRI-negative focal cortical dysplasia (FCD). METHODS: We used clinically acquired 3-dimensional (3D) T1-weighted and 3D fluid-attenuated inversion recovery MRI of 148 patients (median age 23 years [range 2-55 years]; 47% female) with histologically verified FCD at 9 centers to train a deep convolutional neural network (CNN) classifier. Images were initially deemed MRI-negative in 51% of patients, in whom intracranial EEG determined the focus. For risk stratification, the CNN incorporated bayesian uncertainty estimation as a measure of confidence. To evaluate performance, detection maps were compared to expert FCD manual labels. Sensitivity was tested in an independent cohort of 23 cases with FCD (13 ± 10 years). Applying the algorithm to 42 healthy controls and 89 controls with temporal lobe epilepsy disease tested specificity. RESULTS: Overall sensitivity was 93% (137 of 148 FCD detected) using a leave-one-site-out cross-validation, with an average of 6 false positives per patient. Sensitivity in MRI-negative FCD was 85%. In 73% of patients, the FCD was among the clusters with the highest confidence; in half, it ranked the highest. Sensitivity in the independent cohort was 83% (19 of 23; average of 5 false positives per patient). Specificity was 89% in healthy and disease controls. DISCUSSION: This first multicenter-validated deep learning detection algorithm yields the highest sensitivity to date in MRI-negative FCD. By pairing predictions with risk stratification, this classifier may assist clinicians in adjusting hypotheses relative to other tests, increasing diagnostic confidence. Moreover, generalizability across age and MRI hardware makes this approach ideal for presurgical evaluation of MRI-negative epilepsy. CLASSIFICATION OF EVIDENCE: This study provides Class III evidence that deep learning on multimodal MRI accurately identifies FCD in patients with epilepsy initially diagnosed as MRI negative.

Magnetic resonance imaging findings and clinical characteristics in mild malformation of cortical development with oligodendroglial hyperplasia and epilepsy in a predominantly adult cohort.

OBJECTIVE: We aimed to better characterize the magnetic resonance imaging (MRI) findings of mild malformation of cortical development with oligodendroglial hyperplasia (MOGHE), a rare clinicopathological entity associated with pharmacoresistance recently described in patients with frontal lobe epilepsy. METHODS: We studied 12 patients who underwent epilepsy surgery and whose surgical specimens showed histopathological findings of MOGHE, characterized by preserved cortical lamination, blurred gray-white matter interface due to increased number of oligodendrocytes, and heterotopic neurons in the white matter. The age at MRI evaluation ranged from 11 to 58 years, except for one 4.5-year-old patient. RESULTS: Following a detailed MRI analysis using an in-house protocol, we found abnormalities in all cases. The lesion was circumscribed in the frontal lobe in six (50%) and in the temporal lobe in three (25%) patients. In the remaining three patients (25%), the lesion was multilobar (frontotemporal and temporoparieto-occipital). Cortical thickening was mild in all patients, except in the 4.5-year-old patient, who had pronounced cortical thickening and white matter blurring. We also identified cortical/subcortical hyperintense T2/fluid-attenuated inversion recovery signal associated with gray/white matter blurring in all but one patient. When present, cleft cortical dimple, and deep sulci aided in localizing the lesion. Overall, the MRI findings were like those in focal cortical dysplasia (FCD) Type IIa. Surgical outcome was excellent in five patients (Engel Class I in 25% and II in 17%). The remaining seven patients (58%) had worthwhile seizure reduction (Engle Class III). Incomplete lesion resection was significantly associated with worse outcomes. SIGNIFICANCE: MRI findings associated with MOGHE are similar to those described in FCD Type IIa. Although more frequent in the frontal lobe, MOGHE also occurred in the temporal lobe or involved multiple lobes. Multilobar or extensive MOGHE MRI lesions are associated with less favorable surgical outcomes. Because this is a rare condition, multicenter studies are necessary to characterize MOGHE further.

Histopathological Correlations of Qualitative and Quantitative Temporopolar MRI Analyses in Patients With Hippocampal Sclerosis.

Hippocampal sclerosis (HS) is a common cause of pharmacoresistant focal epilepsy. Here, we (1) performed a histological approach to the anterior temporal pole of patients with HS to evaluate cortical and white matter (WM) cell populations, alteration of myelin integrity and markers of neuronal activity, and (2) correlated microscopic data with magnetic resonance imaging (MRI) findings. Our aim was to contribute with the understanding of neuroimaging and pathophysiological mechanisms of temporal lobe epilepsy (TLE) associated with HS. We examined MRIs and surgical specimens from the anterior temporal pole from TLE-HS patients (n = 9) and compared them with 10 autopsy controls. MRIs from healthy volunteers (n = 13) were used as neuroimaging controls. Histological techniques were performed to assess oligodendrocytes, heterotopic neurons, cellular proliferative index, and myeloarchitecture integrity of the WM, as well as markers of acute (c-fos) and chronic (ΔFosB) activities of neocortical neurons. Microscopic data were compared with neuroimaging findings, including T2-weighted/FLAIR MRI temporopolar blurring and values of fractional anisotropy (FA) from diffusion-weighed imaging (DWI). We found a significant increase in WM oligodendrocyte number, both in hematoxylin and eosin, and in Olig2-stained sections. The frequencies of oligodendrocytes in perivascular spaces and around heterotopic neurons were significantly higher in patients with TLE-HS compared with controls. The percentage of 2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNPase; a marker of myeloarchitecture integrity) immunopositive area in the WM was significantly higher in TLE-HS, as well as the numbers of c-fos- and ΔFosB-immunostained neocortical neurons. Additionally, we demonstrated a decrease in axonal bundle integrity on neuroimaging, with a significant reduction in the FA in the anterior temporal pole. No differences were detected between individuals with and without temporopolar blurring on visual MRI analysis, considering the number of oligodendroglial cells and percentage of WM CNPase-positive areas. Also, there was no relationship between T2 relaxometry and oligodendrocyte count. In conclusion, our histopathological data support the following: (1) the hypothesis that repetitive neocortical neuronal activity could induce changes in the WM cellular constitution and myelin remodeling in the anterior temporal pole from patients with TLE-HS, (2) that oligodendroglial hyperplasia is not related to temporal blurring or T2 signal intensity on MRI, and (3) that reduced FA is a marker of increase in Olig2-immunopositive cells in superficial temporopolar WM from patients with TLE-HS.

Common mental disorders and risk behaviours in motorcyclists victims of traffic-accidents / Transtornos mentais comuns e comportamentos de risco em motociclistas vítimas de acidentes de trânsito / Transtornos mentales comunes y comportamientos de riesgo en motociclistas vítimas de accidentes de tránsito

BACKGROUND: Motorcycles accidents are a public health problem. Drivers´ behaviours are pointed out as one of the main causes of their occurrence and may be associated with psychiatric comorbidities as Common Mental Disorders (CMD). AIM: To analyse the association between CMD and risk behaviours adopted by motorcyclists victims of traffic accidents. METHODS: This is a cross-sectional study with injured motorcyclists who were hospitalised in a Hospital located in Northeast of Brazil. A questionnaire was used containing items related to sociodemographic, occupational and behavioural factors, mental health (Self Reporting Questionnaire-20) and aspects of the accident and road conditions. Descriptive and bivariate analyses were performed, calculating the odds ratio (OR) and the 95% confidence interval (CI) and the level of significance was set at 5%. RESULTS: A total of 170 motorcycle drivers were surveyed. There was a predominance of males (95.9%), with a mean age of 31 years. The prevalence of CMD was 14.7%. The bivariate analysis indicated that the disorders were associated with driving with sleep/fatigue (OR=4.7) and driving a motorcycle without wearing a helmet (OR=2,7). CONCLUSION: This study result indicated a link between being the driver's diagnosed with a common mental disorder and risky behaviour in traffic. The research denoted the dimension of accidents involving a motorcycle and, also, highlights how drivers' mental health is a factor impacting the behaviours adopted by them. Thus, poor mental health may influence their road accidents.

CONTEXTO: Os acidentes de trânsito envolvendo motocicletas são um problema de saúde pública. Os comportamentos dos condutores são apontados como uma das principais causas de sua ocorrência, podendo estar associados às comorbidades psiquiátricas, como os Transtornos Mentais Comuns (TMC). OBJETIVO: Analisar a associação entre TMC e comportamentos de risco adotados por motociclistas vítimas de acidente de trânsito. MÉTODOS: Estudo transversal com motociclistas acidentados internados no Departamento de Traumatologia de um hospital no nordeste do Brasil. Aplicou-se um questionário contendo itens relacionados a fatores sociodemográficos, ocupacionais e comportamentais; saúde mental (Self Reporting Questionnaire-20) e aspectos do acidente e condições das vias. Foram realizadas análises descritivas e bivariada, calculando-se a odds ratio e o intervalo de confiança de 95%. O nível de significância adotado foi de 5%. RESULTADOS: Foram entrevistados 170 condutores de motocicletas. Houve predomínio do sexo masculino (95,9%), com média de idade de 31 anos. A prevalência de TMC foi de 14,7%. A análise bivariada indicou que os referidos transtornos estavam associados a dirigir com sono / fadiga (OR = 4,7) e conduzir motocicleta sem usar capacete (OR = 2,7). CONCLUSÕES: Os resultados evidenciam uma associação entre a presença de TMC com alguns comportamentos de risco no trânsito. A pesquisa denota a dimensão dos acidentes envolvendo motocicletas e, também, destaca como a saúde mental dos motociclistas é um fator impactante nos comportamentos adotados por eles. Assim, a saúde mental deficiente pode influenciar seus acidentes rodoviários.

CONTEXTO: Los accidentes de tráfico que involucran las motocicletas son un problema de salud pública. Los comportamientos de los conductores son señalados como una de las principales causas de su ocurrencia, pudiendo estar asociados a las comorbilidades psiquiátricas, como los Trastornos Mentales Comunes (TMC). OBJETIVO: Analizar la asociación entre TMC y comportamientos de riesgo adoptados por los motociclistas víctimas de accidentes de tráfico. METODOLOGÍA: Estudio transversal con motociclistas heridos admitidos en el Departamento de Traumatología de uno hospital em nordeste de Brasil. Se aplicó un cuestionario que contenía elementos relacionados con factores sociodemográficos, ocupacionales y conductuales; Salud mental (Self Reporting Questionnaire-20) y aspectos del accidente y las condiciones de las vías. Se realizaron análisis descriptivos y bivariados, calculando la relación de probabilidades y el intervalo de confianza del 95%. El nivel de significancia adoptado fue del 5%. RESULTADOS: Fueram estudiados 170 conductores de motocicletas. Hubo un predominio de varones (95,9%), con una edad media de 31 años. La prevalencia de TMC fue del 14,7%. El análisis bivariado indicó que los trastornos antes mencionados estaban asociados con la conducción con sueño/fatiga (OR = 4,7) y la conducción de una motocicleta sin usar un casco (OR = 2,7). CONCLUSIÓN: Los resultados muestram una asociación entre la presencia de TMC con algunos comportamientos de riesgo de tráfico. La investigación denota el tamaño de los accidentes que involucran a las motocicletas y también destaca cómo la salud mental de los motociclistas es un factor impactante en los comportamientos adoptados por ellos. Por lo tanto, la salud mental deficiente puede influir en sus accidentes de tráfico.

Alcohol and risky behavior in traffic among motorcyclists involved in accidents in a city in northeastern Brazil.

Objective: The objective of this study was to analyze the association between consumption of alcoholic drinks and adoption of other risky forms of behavior in traffic among motorcyclists involved in accidents. Methods: This was an exploratory cross-sectional study among injured motorcyclists who were hospitalized in the traumatology department of the "Governador Paulo Guerra" Restoration Hospital (Hospital da Restauração Governador Paulo Guerra), Recife, Pernambuco, Brazil. A questionnaire containing items relating to sociodemographic, occupational, and behavioral factors and aspects of the accident and road conditions was applied. Descriptive and bivariate analyses were performed and odds ratios (ORs) and 95% confidence intervals (CIs) were calculated. The significance level was set at 5%. Results: One hundred seventy individuals were investigated. Consumption of alcohol prior to the accident was reported by 32.9% of motorcyclists. This behavior was positively associated with the following risky forms of behavior in traffic: speeding (OR = 4.08; 95% CI, 1.15-9.48); failure to use a helmet (OR = 2.41; 95% CI, 1.15-5.02); and not having a motorcycle driver's license (OR = 2.68; 95% CI, 1.31-5.45). Conclusion: This study showed that, in the population studied, riding a motorcycle under the effects of alcoholic drinks was associated with other risky forms of behavior in traffic: speeding, not using a helmet, and not having a motorcycle driver's license. We believe that the interaction between these behaviors may lead to greater occurrence and greater severity of accidents.

Patients with Subacromial Pain Syndrome Present no Reduction of Shoulder Proprioception: A Matched Case-Control Study.

BACKGROUND: Shoulder pain is common among patients with musculoskeletal pain and the prevalence of patients with subacromial pain syndrome (SAPS) is high. Despite the high prevalence, there is a lack of an extensive evaluation of the proprioception acuity in patients with SAPS. Knowledge of the proprioceptive deficit would assist clinicians in the proper treatment and may offer an alternative explanation for the mechanisms underlying SAPS, which are poorly understood. OBJECTIVE: To compare the proprioceptive function of the shoulder in patients with SAPS and matched controls. STUDY DESIGN: Matched case-control study. SETTING: Physical Functional Rehabilitation Service of an outpatient clinic. PARTICIPANTS: A total of 32 consecutive patients with SAPS who sought physical therapy for shoulder pain and 32 healthy participants (control group) matched for age, sex, and handedness. INTERVENTIONS: All participants completed a questionnaire containing sociodemographic information, pain intensity and characteristics, the Numerical Pain Rating Scale, and the Shoulder Pain and Disability Index. MAIN OUTCOME MEASUREMENTS: The proprioceptive assessment was performed through kinesthesia, passive joint position sense (PJPS), and the active joint position sense (AJPS). RESULTS: The groups showed no statistically significant differences in kinesthesia, PJPS, and AJPS for internal or external rotation. The proprioceptive acuity was not associated with pain intensity or functional disability in patients with SAPS. CONCLUSIONS: Participants with SAPS did not present proprioceptive deficits in a pain-free motion of medial and lateral rotation when compared to their matched controls. The proprioceptive deficit may not be involved with the mechanisms underlying SAPS and seems not to interfere with the clinical outcomes of patients with SAPS. LEVEL OF EVIDENCE: Level III.

Understanding Lies Based on Evolutionary Psychology: A Critical Review / O Entendimento da Mentira com Base na Psicologia Evolucionista: Uma Revisão Crítica / La Comprensión de la Mentira Basada en la Psicología Evolucionista: Una Revisión Crítica

Abstract The present article aims to propose a theoretical discussion regarding the role of lying based upon the Evolutionary Psychology perspective by shedding a new light on the main studies conducted in this area. In order to do so, this article addresses the phylogenies and ontogenies of the capability to lie, both suggesting that the rise of lying as a pro-social deed is intimately related with Homo sapiens incredibly broad and complex communication skills. Like so, the paper continues on expatiating on the underlying cognitive and neuronal mechanisms of lying and lying recognition, as well as the differences amongst genders concerning the ability to recognize deceit. Broadly, the present theoretic study may elucidate the current state of knowledge regarding the topic, thus signaling necessary and more promising paths for future studies to follow with the purpose of contributing to fields where the act of uttering lies is highly present, such as the judicial context.

Resumo O presente artigo tem por objetivo propor uma discussão teórica sobre o papel da mentira a partir da perspectiva da Psicologia Evolucionista, trazendo uma nova luz sobre os principais estudos realizados nessa área. Para tanto, este artigo aborda as filogenias e ontogenias da capacidade de mentir, ambas sugerindo que a ascensão da mentira como ação pró-social está intimamente relacionada às habilidades de comunicação incrivelmente amplas e complexas do Homo sapiens. Assim, o artigo discute os mecanismos cognitivos e neuronais subjacentes ao reconhecimento de mentiras, bem como as diferenças entre os gêneros em relação à capacidade de reconhecer o engano. Em linhas gerais, o presente estudo teórico pode elucidar o estado atual do conhecimento sobre o tema, sinalizando percursos necessários e mais promissores para futuros estudos, com o objetivo de contribuir para campos onde o ato de proferir mentiras está muito presente, como o contexto judiciário.

Resumen El presente artículo tiene como objetivo proponer una discusión teórica sobre el papel de la mentira a luz de la Psicología Evolucionista a partir de los principales estudios desarrollados en esta área. El artículo discurre sobre la filogénesis y la ontogénesis de la capacidad de mentir, discutiendo los mecanismos que viabilizan la ocurrencia de la mentira en la especie humana. El trabajo sugiere que el desarrollo de la mentira como práctica pro-social está íntimamente relacionado con la vasta capacidad de comunicación del Homo sapiens, discurriendo sobre los mecanismos cognitivos y neurales subyacentes, así como la diferencia entre géneros en lo que se refiere al reconocimiento del engaño. En general, el presente estudio teórico puede elucidar el estado actual de conocimiento sobre el asunto, indicando caminos necesarios y más prometedores para nuevos trabajos, a fin de colaborar para campos de actuación donde el acto de proferir mentiras se hace más presente, como, por ejemplo, el contexto judicial.

Caracterização dos acidentes de trânsito envolvendo trabalhadores motociclistas em Pernambuco - 2016 / Characterization of transit accidents involving motorcyclists in Pernambuco-2016

Introdução: os acidentes de trânsito configuram-se como problema de saúde pública devido à sua alta morbimortalidade. Embora haja poucos estudos sobre trabalhadores motociclistas, sabe-se que a maioria dos usuários de motocicletas vive em áreas urbanas e é formada por indivíduos que usam a moto para ir e voltar do trabalho. Objetivos: caracterizar os trabalhadores motociclistas que sofreram acidente de trânsito internados no Hospital da Restauração (HR) de Recife - PE e descrever as características do acidente sofrido por esses condutores. Métodos: estudo transversal realizado no leito de pacientes trabalhadores acidentados, condutores de motocicletas, internados no HR em Recife-PE, no período de maio a setembro de 2016, utilizando questionário com variáveis sociodemográficas, ocupacionais e relacionadas ao acidente. Resultados: foram entrevistados 124 indivíduos. A maioria era do sexo masculino (97,6%), adulto jovem de 18 a 39 anos (81,5%), com renda média mensal menor que 2 salários (75,0%). Cerca de 55% dos entrevistados possuíam vínculo empregatício informal. O maior número de acidentes ocorreu entre 18:01 e 00:00 (45%). Colisão com outros veículos automotores foi o tipo de acidente mais frequente (62,0%). Conclusões: os resultados demonstram que a maioria dos acidentados era do sexo masculino, em idade produtiva, que ganhava menos de 2 salários mínimos e que a maioria dos acidentes se deu por colisão. A importância da educação e da sensibilização junto aos motociclistas e aos demais condutores, a fim de reduzir a incidência e a gravidade dos acidentes envolvendo motocicletas.(AU)

Introduction: Traffic accidents are configured as public health problem due to their high morbidity and mortality. Although there are few studies on motorcycle workers, it is known that most motorcycle users live in urban areas and are made of individuals who use the bike to go to and from work. OBJECTIVES: To characterize motorcyclists who suffered a traffic accident hospitalized at a Recife Hospital - Recife, Brazil, and describe the characteristics of the accidents suffered by these drivers. Methods: A cross-sectional study carried out in the hospital bed of injured workers, drivers of motorcycles, hospitalized at the HR in Recife-PE, from May to September 2016, using a sociodemographic, occupational, and accident-related questionnaire. Results: 124 individuals were interviewed. The majority were males (97.6%), young adults aged 18 to 39 years (81.5%), with a monthly average income lower than 2 minimum wages (75.0%). About 55% of the interviewees had an informal employment relationship. The highest number of accidents occurred between 18:01 and 00:00 (45%). Collision with other automobiles was the most frequent type of accident (62.0%). Conclusions: The results showed that the majority of the accident victims were male, in a productive age, who earned less than 2 minimum wages and that most of the accidents occurred due to collision. The importance of education and awareness among motorcyclists and other drivers in order to reduce the incidence and severity of accidents involving motorcycles.(AU)

Transtornos mentais comuns em motociclistas: uma revisão integrativa de literatura / Common mental disorders in motorcyclists: an integrative literature review

Introdução: Os Transtornos Mentais Comuns representam a morbidade psiquiátrica mais prevalente nas sociedades modernas. Sua presença, agregada ou não as características individuais dos condutores, pode afetar a forma de dirigir um veículo e acarretar desfechos negativos em sua condução, podendo estar associada aos problemas pertinentes ao trânsito inseguro. Objetivos: Identificar e analisar a produção científica existente sobre a prevalência e os fatores associados aos transtornos mentais comuns (TMC) em motociclistas. Métodos: Trata-se de uma revisão integrativa da literatura realizada no período de abril a dezembro de 2016 por meio de pesquisa de publicações nas bases de dados eletrônicas PubMed, LILACS, Bireme, Wiley Online Library, ScienceDirect, Biblioteca Digital Brasileira de Teses e Dissertações ­ BDTD e SCIELO. Resultados: Das 38 publicações encontradas, apenas 03 abordavam o tema proposto e atendiam aos critérios de inclusão, sendo selecionadas para compor esta revisão. Constatou-se que as pesquisas sobre a temática são recentes e desenvolvidas com desenho de estudo transversal. A prevalência de TMC variou entre 5,4% e 30,2%, sendo maior nos estudos nacionais. Para aferir a ocorrência dos TMC foram utilizados o Self-reporting questionnaire (SRQ-20) e o Clinical Interview Schedule Revised (CIS-R) e mostraram-se associados aos TMC o estado civil, não ter veículo próprio e o uso de drogas. Conclusões: Verificou-se que a produção científica acerca dos Transtornos Mentais Comuns em motociclistas é escassa e há pouco consenso sobre a frequência da doença e os fatores associados a ela nesta população específica.(AU)

Introduction: Common Mental Disorders represent the most prevalent psychiatric challenges in modern society. Common Mental Disorders' presence, in vehicle drivers, greatly affects the way of driving a vehicle and certainly leads to negative outcomes in an individual's driving. It may also be imminently associated with problems related to unsafe traffic rules. Objectives: Identify and analyze the existing scientific productions and factors associated with common mental disorders (CMD) in motorcyclists. Methods: This is an integrative review of the literature produced in the period from April to December 2016 through research of publications in the following electronic databases PubMed, LILACS, Bireme, Wiley Online Library, ScienceDirect, Brazilian Digital Library of Theses and Dissertations ­ BDLTD and SCIELO. Results: Of the 38 publications found, only 03 were addressed to the proposed theme and achieved the inclusion criteria, these were selected to compose this review. It was verified that the research on the subject is recent and developed with a cross-sectional study. The prevalence of CMD ranged from 5.4% to 30.2%, being higher in the national studies. The Self-reporting questionnaire (SRQ-20) and the Clinical Interview Schedule Revised (CIS-R) were used to measure the occurrence of CMD, and the marital status, the absence of the vehicle and the use of drugs were associated with the CMD. Conclusions: It has been found that the scientific production about Common Mental Disorders in motorcyclists is scarce and there is little consensus about the frequency of the disease and the factors associated with it in this specific population.(AU)

Neuropharmacological Profile of Gamma-Decanolactone on Chemically-induced Seizure in Mice.

BACKGROUND: Gamma-Decanolactone (GD) is a monoterpene compound that presents anticonvulsant effect in acute and chronic models of epilepsy and it acts as a noncompetitive glutamate antagonist. OBJECTIVE: This study evaluated the anticonvulsant profile and the possible mechanism of action of GD in seizures induced by isoniazid (INH; 250 mg/kg), picrotoxin (PCT; 5 mg/kg) and 4- aminopyridine (4-AP; 13 mg/kg) in male mice. METHOD: Thirty minutes before the convulsants administration, animals received a single administration of saline, GD (100 or 300 mg/kg) or the positive control diazepam (DZP; 2 mg/kg). The parameters evaluated were the latency to the first seizure and the occurrence of clonic forelimb seizures. The rotarod performance test was used to evaluate the neurotoxicity of GD (300 mg/kg). Also, the DZPinduced sleep test was used. RESULTS: DZP increased the latency to the first seizure on all used models and decreased the percentage of seizures in two of the three behavioral models. GD was able to prolong the latency to the first seizure and decreased the percentage of seizures induced by INH and 4-AP, but not by PCT. It reduced the latency to fall off the rotarod test only at the time of 30 min. In the DZP-induced sleep test, GD shortened the onset and prolonged the time of sleep. CONCLUSION: Our findings suggested that GD reduced the convulsive behavior in the seizure models used here and it could modulate GABA pathways and affect potassium channels directly or indirectly, involving more than one cellular target in the central nervous system.

A 28-day Sub-acute Genotoxic and Behavioural Assessment of Garcinielliptone FC.

Garcinielliptone FC (GFC) is a polyisoprenylated benzophenone isolated from Platonia insignis Mart (Clusiaceae) with promising anticonvulsant properties. However, its safe use and other effects on the central nervous system require assessment. This study assessed the toxicological effects of GFC using the comet assay and the micronucleus test in mice treated for 28 days. A behavioural model was employed to detect possible injuries on the central nervous system. Mice treated with GFC (2, 10 and 20 mg/kg; i.p.) daily for 28 days were submitted to rotarod test, open-field test and tail suspension test (TST). After the behaviour tasks, biological samples were assessed to evaluate genotoxic and mutagenic effects using the comet assay and the micronucleus test. Garcinielliptone FC did not impair the performance of the animals in the rotarod and open-field tests, with no antidepressant-like effect in TST. No genotoxic effects in blood and cerebral cortex were observable in the comet assay; however, there was a significant increase in index and frequency of damage in liver after treatment with GFC 20 mg/kg. Garcinielliptone FC did not increase micronucleus frequency in bone marrow. At the tested doses, GFC was not toxic to the CNS and did not induce genotoxic damage to blood or bone narrow cells. DNA damage to liver tissue was caused only by the highest dose, although no mutagenic potential was observed.

Effect of operational parameters and Pd/In catalyst in the reduction of nitrate using copper electrode.

Water with high concentration of nitrate may cause damage to health and to the environment. This study investigated how concentration, current density, flow, pH, the use of Pd/In catalyst and operating mode (constant current density and constant cell potential) have an influence in the electrochemical reduction of nitrate and in the formation of gaseous compounds using copper electrode. Experiments were performed in two-compartment electrolytic cells separated by a cationic membrane with nitrate model solutions prepared as a surrogate of concentrated brines from membrane desalination plants. The results show that the electroreduction process has potential for reduction of nitrate and that it is influenced by the operational conditions. The best conditions found for the treatment - with satisfactory reduction of nitrate, formation of gaseous compounds and reproducibility - were at nitrate concentrations of 600 and 1000 mg L-1, current density of 1.1 mA cm-2 and without pH control, since in these conditions the production of gaseous compounds is higher than the production of nitrite. When Pd/In catalyst was used, the nitrate reduction was 50% after 6 h of experiment and the predominant product were gaseous compounds. When compared to the experiment without the catalyst, the arrangement with Pd/In was the most efficient one.

Citrus essential oils inhalation by mice: Behavioral testing, GCMS plasma analysis, corticosterone, and melatonin levels evaluation.

The use of orange essential oils (EOs) as a complementary treatment is very common in Brazilian popular culture. The levels of melatonin (MEL) and corticosterone (CORT) hormones were investigated simultaneously, by the Luminex™ immunoassay system in mice plasma, after Citrus aurantium and Citrus sinensis EOs inhalation for 30 min. The plasma was analyzed by headspace through gas chromatography coupled to mass spectrometry for investigation of the EO components. Mice were submitted to behavioral testing to research anxiolytic-like, sedative, and antidepressant-like effects. The inhalation of atmosphere obtained from vaporization of 10% solution of this Citrus EO separately did not affect MEL or CORT plasma levels; that is, the MEL and CORT levels did not present variation in function of the EO in the schedule used. On the other hand, the imipramine positive control used altered the level of MEL as expected. The EO constituents were detected in plasma at different ratios that is present in inhaled EO. Behavioral tests showed that the inhalation of 10% C. sinensis EO presents an anxiolytic-like and sedative effect. Thus, C. sinensis EO can be a valuable tool for treatment of the anxiety disturbs, apparently without interference with MEL and CORT physiological levels.

Gamma-Decanolactone Improves Biochemical Parameters Associated with Pilocarpine-Induced Seizures in Male Mice.

BACKGROUND AND OBJECTIVE: Gamma-decanolactone (GD) is a monoterpene effective against seizures induced by pentylenetetrazole. The mechanism of action of GD is likely to be via glutamate antagonism. GD also inhibits intracellular reactive oxygen species (ROS) generation and the lipopolysaccharide-induced expression of inducible nitric oxide synthase (iNOS) and tumor necrosis factor-alpha (TNF-α) in vitro. Considering the neuropharmacological profile of GD studied so far, we investigated the effect of intraperitoneal administration of GD 100 and 300 mg/kg on pilocarpine (PIL)-induced status epilepticus (SE) in mice. METHODS: GD was administered 30 min before PIL. Behavioral (latency to first seizure and the percentage of clonic forelimb seizures), biochemical, and oxidative stress parameters were evaluated. DNA damage in the cerebral cortex of mice was assessed using the comet assay and mutagenic activity of GD was evaluated using Salmonella/microsome assay in TA100, TA98, TA97a, TA102, and TA1535 strains, with and without metabolic activation (S9 mix). RESULTS: The behavioral results showed that only the latency to the first clonic seizure increased in the groups treated with GD 300 mg/kg, but not when the animals received GD 100 mg/kg. Both GD doses were able to increase superoxide dismutase and catalase activities, inducing a decrease in ROS and nitrite production and in DNA damage in the cerebral cortex. GD was not able to induce base pair substitution and frameshift mutations in the absence or in the presence of metabolic activation. CONCLUSION: These findings demonstrate that GD does not improve behavioral parameters in the PIL model, but it was able to protect seizure-related oxidative stress and DNA damage in mice, without inducing gene mutations.