[Pemphigus and neoplasia. 2 new clinical cases and a review of the literature]. / Pemfigo e neoplasie. Due nuovi casi clinici e revisione della letteratura.

We report two cases of pemphigus vulgaris associated with internal malignancies. The former was a 56 year-old man who developed pemphigus shortly after non-Hodgkin lymphoma has been formed. The latter was a 69 year-old woman who presented pemphigus and gastric carcinoma in the same time. In order to clarify the relationships between all forms of pemphigus and malignancy or thymoma, a search of the world literature was carried out. We found 44 reports of the association of pemphigus with internal malignancy and with benign or malignant thymoma. The key problem that needs to be resolved is whether there is a causal relationship or whether these are only occasional coincidental findings.