Assuntos
Anaplasia/patologia , RNA Helicases DEAD-box/genética , Neoplasias Renais/patologia , Mutação , Síndromes Neoplásicas Hereditárias/patologia , Neuroblastoma/patologia , Ribonuclease III/genética , Sarcoma/patologia , Anaplasia/complicações , Anaplasia/genética , Criança , Humanos , Neoplasias Renais/complicações , Neoplasias Renais/genética , Masculino , Síndromes Neoplásicas Hereditárias/complicações , Síndromes Neoplásicas Hereditárias/genética , Neuroblastoma/complicações , Neuroblastoma/genética , Prognóstico , Sarcoma/complicações , Sarcoma/genéticaRESUMO
Infection-associated hemophagocytic syndrome is a rare, potentially fatal complication of systemic infection. It occurs most often in immunocompromised patients associated with a viral infection but the spectrum of conditions have been broadened to include virtually every type of infectious pathogen, malignancy and immunosuppressive therapy. We present three pediatric patients with a similar clinical history of pancytopenia, hepatosplenomegaly, and acute liver failure, and discuss the autopsy findings.
Assuntos
Infecções/complicações , Linfo-Histiocitose Hemofagocítica , Autopsia , Biópsia , Medula Óssea/patologia , Estado Terminal , Feminino , Humanos , Lactente , Linfo-Histiocitose Hemofagocítica/diagnóstico , Linfo-Histiocitose Hemofagocítica/etiologia , Linfo-Histiocitose Hemofagocítica/mortalidade , Linfo-Histiocitose Hemofagocítica/patologia , Masculino , Baço/patologia , Síndrome , Fatores de TempoRESUMO
This is the case of an 11-year-old girl who presented with a right adnexal mass and vague abdominal symptoms since seven months prior to her hospital admission for surgery. CT-scan and sonographic images were those of a benign lesion, probably ovarian torsion or infarction. Serum tumoral markers were normal. A right salpingo-oophorectomy and appendectomy were performed. Pathology examination revealed a cavernous hemangioma of the ovary. The clinicopathologic presentation of this unusual benign ovarian tumor is discussed.
