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1.
JAMA Netw Open ; 7(7): e2419657, 2024 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-38954418

RESUMO

This cohort study examines housing status and acute care use after a cancer diagnosis among individuals treated at a public hospital in San Francisco, California.


Assuntos
Habitação , Neoplasias , Humanos , Feminino , Masculino , Neoplasias/diagnóstico , Pessoa de Meia-Idade , Idoso , Adulto
2.
Am J Surg ; 232: 131-137, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38365550

RESUMO

BACKGROUND: Studies comparing opioid needs between benign and malignant colorectal diseases are inconclusive. METHODS: Single institution analysis of prospectively maintained colorectal surgery database. Multiple regression analyses done on perioperative numeric pain scores (NPS) and opioids prescribed at discharge. RESULTS: 641 patients in Benign and 276 patients in the Malignant group. Unadjusted comparison revealed significantly higher NPS for the Benign than the Malignant group preoperative and postoperative day 0 (after surgery), 1, 2, and 3 (all p â€‹≤ â€‹0.001). Opioids prescribed at discharge were significantly higher in the Benign group (60.0% vs 51.1%, p â€‹= â€‹0.018). After regression analysis, there was no longer a significant difference in NPS (B â€‹= â€‹0.703, p â€‹= â€‹0.095) and opioids prescribed between groups [OR â€‹= â€‹0.803 (95%CI 0.586, 1.1), p â€‹= â€‹0.173]. CONCLUSIONS: Pain and opioids prescribed at discharge are not significantly different between benign and malignant diseases in an enhanced recovery pain management pathway that maximizes non-opioid multimodal analgesic strategies.


Assuntos
Analgésicos Opioides , Neoplasias Colorretais , Dor Pós-Operatória , Humanos , Analgésicos Opioides/uso terapêutico , Analgésicos Opioides/administração & dosagem , Feminino , Masculino , Dor Pós-Operatória/tratamento farmacológico , Pessoa de Meia-Idade , Idoso , Neoplasias Colorretais/cirurgia , Medição da Dor , Manejo da Dor/métodos , Estudos Retrospectivos , Doenças Retais/cirurgia , Colectomia/efeitos adversos , Doenças do Colo/cirurgia , Adulto
3.
Dis Colon Rectum ; 67(1): 151-159, 2024 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-37678267

RESUMO

BACKGROUND: Ureteral stents are thought to prevent or help identify ureteral injuries. Studies suggesting that ureteral stents increase the risk of postoperative acute kidney injury show inconsistent conclusions. The large ureteral stenting volume at our institution provided a unique opportunity for granular analysis not previously reported. OBJECTIVE: To determine whether prophylactic ureteral stenting at colorectal surgery increases acute kidney injury. DESIGN: Retrospective analysis of colorectal operations with prophylactic ureteral stents was compared to operations without stents. Adjusted analysis was performed with inverse probability treatment weighting. SETTINGS: Single institution enhanced recovery colorectal surgery service. PATIENTS: Prospective institutional database between July 1, 2018, and December 31, 2021. MAIN OUTCOME MEASURE: The primary outcome was acute kidney injury, defined as increase in creatinine ≥0. 3 mg/dL (definition 1) and 1.5-fold increase in creatinine (definition 2) within 48 hours postoperatively. RESULTS: There were 410 patients in the study population: 310 patients in the stent group and 100 in the no-stent group. There were 8 operative ureteral injuries: 4 (1.29%) in the stent group and 4 (4.0%) in the no-stent group ( p = 0.103). Unadjusted analysis revealed no significant difference in acute kidney injury between groups. After adjustment, there was still no significant difference in acute kidney injury between groups when defined as definition 1 (no-stent 23.76% vs stent 26.19%, p = 0.745) and as definition 2 (no-stent 15.86% vs stent 14.8%, p = 0.867). Subgroup analysis showed that lighted stents were associated with significantly more acute kidney injury than no-stent patients when defined as definition 1 ( p = 0.017) but not when defined as definition 2 ( p = 0.311). LIMITATIONS: Single-institution results may not be generalizable. CONCLUSION: Prophylactic ureteral stenting does not increase the risk of acute kidney injury for patients undergoing enhanced recovery colorectal surgery, although caution and further study may be warranted for lighted stents. Studies further examining contrasting roles of ureter stenting and imaging in open and minimally invasive colorectal surgery are warranted. See Video Abstract. LOS STENTS URETERALES NO AUMENTAN EL RIESGO DE LESIN RENAL AGUDA DESPUS DE LA CIRUGA COLORECTAL: ANTECEDENTES:Se cree que los stents ureterales previenen o ayudan a identificar las lesiones ureterales. Los estudios que sugieren que los stents ureterales aumentan el riesgo de lesión renal aguda post operatoria muestran conclusiones contradictorias. El gran volumen de endoprótesis ureterales en nuestra institución brindó una oportunidad única para el análisis granular que no se informó anteriormente.OBJETIVO:Determinar si la colocación de stent ureteral profiláctico en cirugía colorrectal aumenta el daño renal agudo.DISEÑO:El análisis retrospectivo de operaciones colorrectales con stents ureterales profilácticos se comparó con operaciones sin stents. El análisis ajustado se realizó con ponderación de tratamiento de probabilidad inversa.AJUSTES:Cirugía colorrectal de recuperación mejorada de una sola instituciónPACIENTES:Base de datos institucional prospectiva entre el 01/07/2018 y el 31/12/2021.MEDIDA DE RESULTADO PRINCIPAL:El resultado primario fue la lesión renal aguda definida como un aumento en la creatinina ≥ 0,3 mg/dL (Definición n.° 1) y un aumento de 1,5 veces en la creatinina (Definición n.° 2) dentro de las 48 horas posteriores a la operación.RESULTADOS:Hubo 410 pacientes en la población de estudio: 310 pacientes en el grupo Stent y 100 en el grupo No-Stent. Hubo 8 lesiones ureterales operatorias, 4 (1,29%) en el grupo Stent y 4 (4,0%) en el grupo No-Stent (p = 0,103). El análisis no ajustado no reveló diferencias significativas en la lesión renal aguda entre los grupos. Después del ajuste, todavía no hubo una diferencia significativa en la lesión renal aguda entre los grupos cuando se definió como Definición n.º 1 (sin stent 23,76 % frente a stent 26,19 %, p = 0,745) y por definición n.º 2 (sin stent 15,86 % frente a stent 14,8 %, p = 0,867). El análisis de sub grupos mostró que los stents iluminados se asociaron con una lesión renal aguda significativamente mayor que los pacientes sin stent cuando se definieron como Definición n.º 1 (p = 0,017), pero no cuando se los definió como Definición n.º 2 (p = 0,311).LIMITACIONES:Los resultados de una sola institución pueden no ser generalizables.CONCLUSIÓN:La colocación profiláctica de endoprótesis ureterales no aumenta el riesgo de lesión renal aguda en pacientes que se someten a cirugía colorrectal de recuperación mejorada, aunque es posible que se requiera precaución y estudios adicionales para las endoprótesis iluminadas. Se justifican estudios que examinen más a fondo las funciones contrastantes de la colocación de stents de uréter y las imágenes en la cirugía colorrectal abierta y mínimamente invasiva. (Traducción-Dr. Mauricio Santamaria ).


Assuntos
Injúria Renal Aguda , Neoplasias Colorretais , Cirurgia Colorretal , Ureter , Humanos , Estudos Retrospectivos , Cirurgia Colorretal/efeitos adversos , Creatinina , Estudos Prospectivos , Colectomia/métodos , Injúria Renal Aguda/epidemiologia , Injúria Renal Aguda/etiologia , Stents
4.
Am Surg ; 89(12): 6091-6097, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-37482697

RESUMO

BACKGROUND: Management of the bladder defect during colectomy for colovesical fistula (CVF) and recommendations for duration of urinary catheter drainage are inconsistent. This study aimed to determine if urinary catheter drainage duration was associated with postoperative complications. METHODS: Retrospective single institution cohort study of patients undergoing resection for diverticular CVF from 2015 through 2021. Urinary catheter drainage was defined as Early (≤7 days postoperative and then subdivided into 1-2 days, 3-5 days, 6-7 days), and Late (>7 days postoperative). Primary outcome was a composite measure of postoperative bladder leak, surgical site infection-III, sepsis, reoperation, and postoperative length-of-stay ≥7 days. RESULTS: There were 73 patients-64 Early group and 9 Late group. Composite measure between groups (Early 25% vs Late 33.33%, P = .688) was not significantly different. The Late group had more patients with large bladder defects (33.3% vs 7.8%, P = .054), significantly more patients who underwent suture repair (55.6% vs 14.1%, P = .01), and significantly more patients that had an intraoperative pelvic drain (66.7% vs 15.6%, P = .003). After propensity score inverse weighting, the Late group had significantly more cystogram-detected postoperative bladder leaks (P = .002) and ileus (P = .042) than the Early group. There were no bladder leaks or ileus in those who had urinary catheter removal on postoperative days 1-2. CONCLUSIONS: Early urinary catheter removal was associated with no increase in bladder leaks and fewer postoperative complications after definitive management of CVF. Further investigation is required to determine if intraoperative bladder leak testing and postoperative cystograms are useful adjuncts in decision making.


Assuntos
Íleus , Fístula Intestinal , Humanos , Cateteres Urinários/efeitos adversos , Estudos Retrospectivos , Estudos de Coortes , Fístula Intestinal/etiologia , Fístula Intestinal/cirurgia , Colectomia/efeitos adversos , Íleus/cirurgia , Complicações Pós-Operatórias/epidemiologia , Complicações Pós-Operatórias/cirurgia
5.
New Phytol ; 229(6): 3195-3207, 2021 03.
Artigo em Inglês | MEDLINE | ID: mdl-33220075

RESUMO

Character displacement can play a major role in species ecology and evolution; however, research testing whether character displacement can influence the evolution of root traits in plant systems remains scarce in the literature. Here we investigated the potential that character displacement may influence the evolution of root traits using two closely related morning glory species, Ipomoea purpurea and Ipomoea hederacea. We performed a field experiment where we grew the common morning glory, I. purpurea, in the presence and absence of competition from I. hederacea and examined the potential that the process of character displacement could influence the evolution of root traits. We found maternal line variation in root phenotypes and evidence that below-ground competition acts as an agent of selection on these traits. Our test of character displacement, however, showed evidence of character convergence on our measure of root architecture rather than displacement. These results suggest that plants may be constrained by their local environments to express a phenotype that enhances fitness. Therefore, the conditions of the competitive environment experienced by a plant may influence the potential for character convergence or displacement to influence the evolution of root traits.


Assuntos
Ipomoea , Seleção Genética , Ecologia , Fenótipo
6.
Am Nat ; 195(4): 577-590, 2020 04.
Artigo em Inglês | MEDLINE | ID: mdl-32216668

RESUMO

Although root traits play a critical role in mediating plant-plant interactions and resource acquisition from the soil environment, research examining whether and how belowground competition can influence the evolution of root traits remains largely unexplored. Here we examine the possibility that root traits may evolve as a target of selection from interspecific competition using Ipomoea purpurea and I. hederacea, two closely related morning glory species that commonly co-occur in the United States, as a model system. We show that belowground competitive interactions between the two species can alter the pattern of selection on root traits in each species. Specifically, competition with I. purpurea changes the pattern of selection on root angle in I. hederacea, and competitive interactions with I. hederacea change the pattern of selection on root size in I. purpurea. However, we did not uncover evidence that intraspecific competition altered the pattern of selection on any root traits within I. hederacea. Overall, our results suggest that belowground competition between closely related species can influence the phenotypic evolution of root traits in natural populations. Our findings provide a microevolutionary perspective of how competitive belowground interactions may impact plant fitness, potentially leading to patterns of plant community structure.


Assuntos
Ipomoea/anatomia & histologia , Raízes de Plantas/anatomia & histologia , Seleção Genética , Evolução Biológica , Ipomoea/genética , Ipomoea/crescimento & desenvolvimento , Fenótipo , Raízes de Plantas/crescimento & desenvolvimento
7.
J Women Aging ; 29(3): 200-215, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-27485259

RESUMO

The aim of this article is to analyze the difficulties in professionalizing the long-term care system in Spain. Since 2006, the new Spanish law has recognized care as a subjective right, and regulations are being designed to create a framework for its professionalization. Nowadays, family remains the most important group of providers who care for their elders, and women remain the main informal caregivers. Why do families resist using public long-term care services and professional carers included in the new law? The hypothesis highlights sociocultural factors as an obstacle to professionalization of long-term care services in addition to political and economic factors. The results show qualitative data about expectations, preferences, and discourses that women caregivers have in relation to their responsibility. The empirical material includes 25 interviews with different profiles of caregivers and six focus groups with family caregivers. The article suggests that the Spanish ideal of care is a problem for the professionalization of services because the family remains as the main provider of care-without specific skills, knowledge, and abilities.


Assuntos
Cuidadores/psicologia , Cultura , Família/psicologia , Assistência de Longa Duração/psicologia , Aceitação pelo Paciente de Cuidados de Saúde/psicologia , Serviços de Saúde Comunitária/métodos , Serviços de Saúde Comunitária/organização & administração , Humanos , Assistência de Longa Duração/legislação & jurisprudência , Assistência de Longa Duração/organização & administração , Administração em Saúde Pública/legislação & jurisprudência , Espanha
8.
Dynamis (Granada) ; 33(1): 139-168, 2013. tab, ilus
Artigo em Espanhol | IBECS | ID: ibc-127356

RESUMO

Este estudio analiza el papel epistemológico de las representaciones visuales en el Tratado de ginecología de Miquel A. Fargas Roca (1858-1916). Se interpretan las ilustraciones no solo como acompañamiento didáctico u ornamental del texto, sino como un elemento del proceso de construcción del conocimiento científico. Tras situar al autor y obra en su contexto social y científico, el artículo realiza un análisis combinado del texto y de las ilustraciones del manual, buscando la imagen de la mujer y el significado de su cuerpo para la sociedad burguesa de finales del siglo XIX y principios del siglo XX. Se concluye que las representaciones visuales revelan la posición ideológica del autor y el rol social que otorgaba a las mujeres de su tiempo (AU)


This study analyzes the epistemological role of visual representations in the Tratado de ginecología by Miquel A. Fargas Roca (1858-1916). The illustrations are interpreted not only as a didactic or ornamental complement of the text but also as an element of the process of scientific knowledge construction. After placing the author and his work in their social and scientific context, the paper provides a combined analysis of the text and illustrations of the manual, seeking the image of the woman and the meaning of her body for bourgeois society in the late 19th and early 20th century. It is concluded that the visual representations reveal the ideological position of the author and the social role that he assigned to the women of his time (AU)


Assuntos
Humanos , Feminino , Ginecologia/história , Ilustração Médica , Livros Ilustrados/história , História da Medicina , Genitália Feminina
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