RESUMO
This report extends the genetic map of the common shrew (Sorex araneus) by adding chromosome assignments for ten genes to the seven already mapped (Pack et al. 1995). A somatic cell hybrid panel was used for the mapping. The genes for peptidase A (PEPA) and isocitrate dehydrogenase-1 (IDH1) map to chromosome de; the genes for phosphoglucomutase-1 (PGM1), superoxide dismutase-1 (SOD1), and mannosephosphate isomerase (MPI) are located on chromosome af; the genes for nucleoside phosphorylase (NP) and glutathione reductase (GSR) are on chromosome ik; and the genes for peptidase S (PEPS), malic enzyme-1 (ME1), peptidase B (PEPB) are found on chromosomes jl, go, and mp respectively.
Assuntos
Enzimas/genética , Musaranhos/genética , Aminopeptidases/genética , Animais , Ácido Aspártico Endopeptidases/genética , Mapeamento Cromossômico , Cricetinae , Cricetulus , Dipeptidil Peptidases e Tripeptidil Peptidases , Endopeptidases , Glutationa Redutase/genética , Células Híbridas , Isocitrato Desidrogenase/genética , Leucil Aminopeptidase , Malato Desidrogenase/genética , Manose-6-Fosfato Isomerase/genética , Camundongos , Pentosiltransferases/genética , Fosfoglucomutase/genética , Superóxido Dismutase/genéticaRESUMO
The chromosome localization of the gene encoding growth hormone (GH) was determined by Southern blotting of DNA obtained from a panel of common shrew x Chinese hamster and common shrew x mouse hybrid somatic cell clones using mink GH DNA as a probe. The GH gene was found to be localized on chromosome hn of the common shrew.
