RESUMO
Synovial sarcoma (SS) is an uncommon malignant neoplasm of the soft tissues. It mainly affects the periarticular tissues of the extremities in young adults, but has been described at nearly all sites; nevertheless, the gastrointestinal tract is an exceptional location. We report a case of a primary synovial sarcoma of the duodenum in a 69-year-old woman. Histological study showed a monophasic pattern. The tumor cells demonstrated diffuse vimentin and Bcl-2 expression, partial EMA expression and focal AE1/3 positivity. The differential diagnosis includes gastrointestinal stromal tumors. Cytogenetic analysis confirmed the diagnosis, with detection of the X;18 translocation. The patient presented postoperative complications and died one month following the intervention.
Assuntos
Cromossomos Humanos Par 18 , Cromossomos Humanos X , Neoplasias Duodenais/diagnóstico , Testes Genéticos/métodos , Hibridização in Situ Fluorescente , Sarcoma Sinovial/diagnóstico , Translocação Genética , Adolescente , Adulto , Idoso , Biópsia , Neoplasias Duodenais/genética , Neoplasias Duodenais/patologia , Neoplasias Duodenais/terapia , Evolução Fatal , Feminino , Humanos , Imuno-Histoquímica , Masculino , Pessoa de Meia-Idade , Pancreaticoduodenectomia/efeitos adversos , Radioterapia Adjuvante , Sarcoma Sinovial/genética , Sarcoma Sinovial/patologia , Sarcoma Sinovial/terapia , Tomografia Computadorizada por Raios X , Falha de Tratamento , Adulto JovemRESUMO
Papillary fibroelastoma (PF) is a rare benign heart tumor and represents less than 10% of primary cardiac tumors. It mainly affects the cardiac valves and is often discovered during open heart surgery or autopsy. We present a case of a patient who was detected with a left ventricular apex tumor during the evaluation of the transient ischemic attack. The patient underwent surgery, and subsequently, macroscopic and microscopic examination confirmed the diagnosis of PF.
Assuntos
Neoplasias Cardíacas/diagnóstico , Achados Incidentais , Neoplasias de Tecido Fibroso/diagnóstico , Procedimentos Cirúrgicos Cardíacos , Neoplasias Cardíacas/cirurgia , Ventrículos do Coração/patologia , Humanos , Imageamento por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Neoplasias de Tecido Fibroso/cirurgia , Resultado do TratamentoRESUMO
El hamartoma de mama es una entidad benigna y poco común que afecta preferentemente a mujeres a partir de la pubertad. Se caracteriza por un crecimiento lento y su transformación maligna se considera un hallazgo incidental. Presentamos el caso de una mujer de 48 años con una tumoración en mama derecha. Histológicamente mostró elementos epiteliales propios de la mama dispuestos al azar, rodeados por un tejido fibroadiposo, y un foco de carcinoma intraductal. Las imágenes mamográficas fueron de hamartoma típico sin signos de malignidad. A los ocho meses de la intervención no existen signos de recidiva
Breast hamartomas are uncommon benign lesions found in all age groups after puberty. They present clinically as a slow-growing mass and its malignant transformation is usually a coincidental finding. We report the case of a 48 year-old woman with a mass in her right breast. Histological study showed epithelial elements of normal breast tissue randomly dispersed among a fibrofatty stroma, and a microscopic focus of intraductal carcinoma . Mammography showed the typical hamartoma features without any suspicious signs of malignancy. The patient remains alive and well eight months after surgery
