Psychiatric disorders in pregnant women admitted to the high-risk obstetric service in a Colombian university clinic between 2013 and 2017.

OBJECTIVE: To determine the psychiatric diagnoses and treatments of patients admitted to the high-risk obstetric service who underwent a consultation with a liaison psychiatrist. METHODS: A descriptive observational study that included pregnant women from the high-risk obstetric service of a highly specialised clinic in Medellín, who had a liaison psychiatry consultation between 2013 and 2017. The main variables of interest were psychiatric and obstetric diagnoses and treatments, in addition to biopsychosocial risk factors. RESULTS: A total of 361 medical records were screened, with 248 patients meeting the inclusion criteria. The main prevailing psychiatric diagnosis was major depressive disorder (29%), followed by adaptive disorder (21.8%) and anxiety disorders (12.5%). The pharmacologic treatments most used by the psychiatry service were SSRI antidepressants (24.2%), trazodone (6.8%) and benzodiazepines (5.2%). The most common primary obstetric diagnosis was spontaneous delivery (46.4%), and the predominant secondary obstetric diagnoses were hypertensive disorder associated with pregnancy (10.4%), gestational diabetes (9.2%) and recurrent abortions (6.4%). Overall, 71.8% of the patients had a high biopsychosocial risk. CONCLUSIONS: The studied population's primary psychiatric disorders were major depressive disorder, adjustment disorder and anxiety disorders, which implies the importance of timely recognition of the symptoms of these perinatal mental pathologies, together with obstetric and social risks, in the prenatal consultation. Psychiatric intervention should be encouraged considering the negative implications of high biopsychosocial risk in both mothers and children.

La persistencia de delirium a los 3 meses del egreso de los pacientes ancianos hospitalizados en una clínica universitaria / Persistent Delirium in Elderly patients Three Months After Hospital Discharge from a University Clinic

RESUMEN Objetivos: El delirium es muy prevalente entre los pacientes ancianos con enfermedad general. Si no se revierte en el momento del alta hospitalaria, se lo considera «delirium persistente¼ (DP). El propósito del estudio es describir la prevalencia y las características de los pacientes con DP 3 meses después del egreso hospitalario de la Clínica Universitaria Bolivariana (CUB). Métodos: Se realizó un estudio descriptivo longitudinal para evaluar la prevalencia y las características de los pacientes de 65 o más arios del servicio de hospitalización de la CUB que cumplieran criterios de delirium del DSM-5 al ingreso, el egreso y 3 meses después. Se determinaron las variables sociodemográficas y se aplicaron las escalas CGI-S y DRS-R98. Resultados: Se evaluó a 30 pacientes con diagnóstico de delirium con interconsulta por psiquiatría de enlace entre abril y octubre de 2013, y se excluyó a 6 por no cumplir los criterios de inclusión. Se incluyó en el estudio a 24 pacientes, de los que 9 fallecieron durante la hospitalización (37,5%). De los 15 sobrevivientes, 5 (el 20,8% de la muestra) presentaron remisión del delirium al egreso y 10 (41,6%) continuaron con síntomas y conformaron el grupo de DP. Del grupo de DP, 5 (20,8%) presentaron DP completo y los otros 5 (20,8%), DP subsindrómico (DPSS). A los 3 meses del egreso, solo 2 pacientes (8,3%) continuaron con DP completo y otros 2 (8,3%), con DPSS. En el grupo de pacientes con DP, la prevalencia fue del 30% (diagnóstico de delirium al ingreso) y una incidencia del 70% (aparición del delirium durante la hospitalización). Conclusiones: Un grupo importante de pacientes con delirium continúan sintomáticos 3 meses después del alta. El 40% de los pacientes con síntomas persistentes en el seguimiento a 3 meses indica una trayectoria de mejoría gradual del delirium, lo cual tiene implicaciones en la práctica clínica.

ABSTRACT Objective: The purpose of the study was to determine the prevalence and characteristics of patients with persistent delirium (PD) at three months after hospital discharge. Methodology: Longitudinal descriptive study to assess the prevalence and characteristics of in-patients aged 65 years and older in the Clinica Universitaria Bolivariana who met DSM-5 criteria for delirium at admission, at discharge, and at a 3-month follow up assessment. Socio-demographic features were determined, and CGI-S and DRS-R98 scales used. Results: A total of 30 patients were evaluated between April and October 2013, but 6 did not fulfil the inclusion criteria. The study included 24 patients, with 9 (37.5%) dying during hospitalisation. Of the 15 surviving patients, five (20.8% of the total sample) had their delirium resolved at discharge, and ten (41.6% of the sample) continued with symptoms. These established the PD group, of whom five of them (20.8%) had full PD, and the other five (20.8%) sub-syndromal PD (SSPD). At the final assessment, only two patients (8.3%) continued with full PD, and another two (8.3%) with SSPD. Among the PD group, 30% had a full delirium at admission (prevalence), and 70% developed full delirium during hospitalization (incidence). Conclusions: A significant number of patients did not recover from delirium at leaving hospital, and remained symptomatic three months after discharge. The study findings suggest a course of gradual improvement of delirium, with a persistence of symptoms over time in 40% of the patients, which would have implications for the clinical practice.

Persistent Delirium in Elderly patients Three Months After Hospital Discharge from a University Clinic. / La persistencia de delirium a los 3 meses del egreso de los pacientes ancianos hospitalizados en una clínica universitaria.

OBJECTIVE: The purpose of the study was to determine the prevalence and characteristics of patients with persistent delirium (PD) at three months after hospital discharge. METHODOLOGY: Longitudinal descriptive study to assess the prevalence and characteristics of in-patients aged 65 years and older in the Clinica Universitaria Bolivariana who met DSM-5 criteria for delirium at admission, at discharge, and at a 3-month follow up assessment. Socio-demographic features were determined, and CGI-S and DRS-R98 scales used. RESULTS: A total of 30 patients were evaluated between April and October 2013, but 6 did not fulfil the inclusion criteria. The study included 24 patients, with 9 (37.5%) dying during hospitalisation. Of the 15 surviving patients, five (20.8% of the total sample) had their delirium resolved at discharge, and ten (41.6% of the sample) continued with symptoms. These established the PD group, of whom five of them (20.8%) had full PD, and the other five (20.8%) sub-syndromal PD (SSPD). At the final assessment, only two patients (8.3%) continued with full PD, and another two (8.3%) with SSPD. Among the PD group, 30% had a full delirium at admission (prevalence), and 70% developed full delirium during hospitalization (incidence). CONCLUSIONS: A significant number of patients did not recover from delirium at leaving hospital, and remained symptomatic three months after discharge. The study findings suggest a course of gradual improvement of delirium, with a persistence of symptoms over time in 40% of the patients, which would have implications for the clinical practice.

Validez y utilidad diagnóstica de la escala Eating Attitudes Test-26 para la evaluación del riesgo de trastornos de la conducta alimentaria en población / Diagnostic validity and usefulness of the Eating Attitudes Test-26 for the assessment of eating disorders risk in a Colombian male population masculina de Medellín, Colombia

OBJETIVO: Evaluar la validez y la utilidad diagnóstica de la escala Eating Attitudes Test-26 (EAT- 26) para la evaluación del riesgo de trastornos de conducta alimentaria (TCA) en población masculina. DISEÑO: Estudio observacional de validación de pruebas. Emplazamiento: Realizado en la ciudad de Medellín en nivel de atención comunitaria de consulta psiquiátrica mixta (pública y privada). PARTICIPANTES: Veintiún hombres con edad ≥ 14 años que cumplieran criterios DSM-IV-TR para anorexia nerviosa, bulimia nerviosa y eating disorder not otherwise specified (EDNOS), y 93 controles sin TCA. Mediciones principales: La muestra de casos fue por conveniencia y en controles, aleatoria simple. Se comparó el «criterio de oro» (entrevista estructurada por psiquiatra para determinar el cumplimiento o no de criterios de inclusión de caso de TCA) con el EAT-26, y al instrumento se le hizo validación cultural y semántica, validación factorial, evaluación de confiabilidad así como determinación del mejor punto de corte por medio de la curva ROC. RESULTADOS: En EAT-26 subyacen 4 dominios: dieta-bulimia y preocupación por comida, dieta, control oral-dieta y control oral-bulimia. El alfa de Cronbach fue de 0,89 y el mejor valor de corte el de ≥ 20 puntos (sensibilidad = 100%; especificidad = 97,8%). El valor predictivo positivo fue del 91,3% y el negativo, del 100,0%. CONCLUSIONES: El EAT-26 es un instrumento multidimensional con excelentes valores de confiabilidad, sensibilidad y especificidad, ideal para cribado de posibles TCA en población de riesgo, y podría ser de utilidad en atención primaria para la detección temprana en población masculina

OBJECTIVE: To establish the diagnostic validity and usefulness of Eating Attitudes Test-26 (EAT- 26) for the risk assessment of eating disorders in a male population. Description: Observational validation study questionnaire. SETTING: Performed in Medellin city at a community care level of mixed (public and private) psychiatric clinics. Subjects: The study included 21 male subjects aged ≥ 14 with DSM-IV-TR diagnostic criteria for anorexia nervosa, bulimia nervosa, and Eating Disorder Not Otherwise Specified (EDNOS), and 93 controls without ED. Main outcome measurements: A convenience sample was used for the cases and a simple, randomised one for controls. A reference standard (structured psychiatrist interview confirming the fulfilment of ED case inclusion criteria) was compared with the EAT-26 questionnaire. Reliability, cultural, semantics, and factorial validation were performed, and the best cut-off score was established with the ROC curve. RESULTS: Four domains remain in the instrument: dieting-bulimia and food pre-occupation, dieting, oral control-dieting, and oral control-bulimia. The Cronbach's alpha was 0.89, and a score of ≥ 20 is the best cut-off (sensitivity = 100% and specificity = 97.8%). The positive predictive value was 91.3% and the negative predictive value was 100.0%. CONCLUSIONS: EAT-26 questionnaire is an ideal multidimensional instrument for Eating Disorder screening in risk populations, with excellent reliability, sensitivity and specificity values. EAT-26 could be a useful tool to be considered when strategies for early detection of Eating Disorders are implemented in the male population

[Diagnostic validity and usefulness of the Eating Attitudes Test-26 for the assessment of eating disorders risk in a Colombian male population]. / Validez y utilidad diagnóstica de la escala Eating Attitudes Test-26 para la evaluación del riesgo de trastornos de la conducta alimentaria en población masculina de Medellín, Colombia.

OBJECTIVE: To establish the diagnostic validity and usefulness of Eating Attitudes Test-26 (EAT-26) for the risk assessment of eating disorders in a male population. DESCRIPTION: Observational validation study questionnaire. SETTING: Performed in Medellin city at a community care level of mixed (public and private) psychiatric clinics. SUBJECTS: The study included 21 male subjects aged ≥14 with DSM-IV-TR diagnostic criteria for anorexia nervosa, bulimia nervosa, and Eating Disorder Not Otherwise Specified (EDNOS), and 93 controls without ED. MAIN OUTCOME MEASUREMENTS: A convenience sample was used for the cases and a simple, randomised one for controls. A reference standard (structured psychiatrist interview confirming the fulfilment of ED case inclusion criteria) was compared with the EAT-26 questionnaire. Reliability, cultural, semantics, and factorial validation were performed, and the best cut-off score was established with the ROC curve. RESULTS: Four domains remain in the instrument: dieting-bulimia and food pre-occupation, dieting, oral control-dieting, and oral control-bulimia. The Cronbach's alpha was 0.89, and a score of ≥20 is the best cut-off (sensitivity=100% and specificity=97.8%). The positive predictive value was 91.3% and the negative predictive value was 100.0%. CONCLUSIONS: EAT-26 questionnaire is an ideal multidimensional instrument for Eating Disorder screening in risk populations, with excellent reliability, sensitivity and specificity values. EAT-26 could be a useful tool to be considered when strategies for early detection of Eating Disorders are implemented in the male population.

Validez y utilidad diagnóstica de la escala EAT-26 para la evaluación del riesgo de trastornos de la conducta alimentaria en población femenina de Medellín, Colombia / Diagnostic validity and usefulness of the Eating Attitudes Test-26 for the assessment of eating disorders risk in a Colombian female population

OBJETIVO: Evaluar la validez y la utilidad diagnóstica de la escala EAT-26 para la evaluación del riesgo de trastornos de conducta alimentaria (TCA) en población femenina. DISEÑO: Estudio observacional de validación de pruebas. Emplazamiento: Realizado en la ciudad de Medellín en nivel de atención comunitaria de consulta psiquiátrica mixta (pública y privada). Participantes: Veinticinco mujeres con edades entre 15 y 25 años que cumplieran criterios DSM-IV-TR para anorexia y bulimia nerviosa y 111 controles sin TCA. Mediciones principales: La muestra de casos fue por conveniencia y en controles, aleatoria simple. Se comparó el «criterio de oro» (entrevista estructurada por psiquiatra para determinar el cumplimiento o no de criterios de inclusión de caso de TCA) con el EAT-26, y al instrumento se le hizo validación cultural y semántica, validación factorial, evaluación de confiabilidad, así como determinación del mejor punto de corte por medio de la curva ROC. RESULTADOS: En EAT-26 subyacen 4 dominios: bulimia, dieta, preocupación por la comida y control oral. El alfa de Cronbach fue de 92,1%, y el mejor valor de corte, el de 11 y más puntos (sensibilidad del 100% y especificidad del 85,6%). CONCLUSIÓN: El EAT-26 modificado y abreviado es un instrumento multidimensional, con excelentes valores de confiabilidad y sensibilidad, y con un adecuado valor de especificidad, apropiado para el cribado de posible TCA en población de riesgo y útil en atención primaria para su detección temprana en mujeres jóvenes

OBJECTIVE: To establish diagnostic validity and usefulness of EAT-26 for the risk assessment of Eating Disorder (ED) in a female population. Description: Observational validation study questionnaire. Setting: Performed in a Medellin city community care level of mixed (public and private)psychiatric consultation. Subjects: Twenty five subjects aged 15 to 25 with DSM-IV-TR diagnostic criteria for anorexia and bulimia nervosa and 111 controls without ED. Main outcomes measures: The case sample was for convenience and in controls an aleatory simple one. Gold standard (structured psychiatrist interview confirming the fulfillment of ED case inclusion criteria) was compared with EAT-26 questionnaire; reliability was assessed, cultural, semantics and factorial validation was made and the best cut-off score was established with the ROC curve. RESULTS: Four domains remain in the instrument: bulimia, dieting, food preoccupation and oral control. The Cronbach's alpha was 92.1% and a score of 11 and over is the best cut-off (sensitivity100%, and specificity 85.6%). CONCLUSIONS: This modified and abbreviated EAT-26 questionnaire is an ideal multidimensional instrument for ED screening in risk population, with excellent reliability and sensitivity values and satisfactory specificity. EAT-26 is a useful measure to be considered when strategies for ED early detection are implemented in young women

[Diagnostic validity and usefulness of the Eating Attitudes Test-26 for the assessment of eating disorders risk in a Colombian female population]. / Validez y utilidad diagnóstica de la escala EAT-26 para la evaluación del riesgo de trastornos de la conducta alimentaria en población femenina de Medellín, Colombia.

OBJECTIVE: To establish diagnostic validity and usefulness of EAT-26 for the risk assessment of Eating Disorder (ED) in a female population. DESCRIPTION: Observational validation study questionnaire. SETTING: Performed in a Medellin city community care level of mixed (public and private) psychiatric consultation. SUBJECTS: Twenty five subjects aged 15 to 25 with DSM-IV-TR diagnostic criteria for anorexia and bulimia nervosa and 111 controls without ED. MAIN OUTCOMES MEASURES: The case sample was for convenience and in controls an aleatory simple one. Gold standard (structured psychiatrist interview confirming the fulfillment of ED case inclusion criteria) was compared with EAT-26 questionnaire; reliability was assessed, cultural, semantics and factorial validation was made and the best cut-off score was established with the ROC curve. RESULTS: Four domains remain in the instrument: bulimia, dieting, food preoccupation and oral control. The Cronbach's alpha was 92.1% and a score of 11 and over is the best cut-off (sensitivity 100%, and specificity 85.6%). CONCLUSIONS: This modified and abbreviated EAT-26 questionnaire is an ideal multidimensional instrument for ED screening in risk population, with excellent reliability and sensitivity values and satisfactory specificity. EAT-26 is a useful measure to be considered when strategies for ED early detection are implemented in young women.