Retiform hemangioendothelioma. A new case in a child with diffuse endovascular papillary endothelial proliferation.

We present a new case of retiform hemangioendothelioma (RH), an entity first described by Calonje et al. in 1994. The tumor was intradermal and located on the toe of an 11-year-old boy. Histologically, in addition to the distinctive retiform pattern of proliferating vessels in RH there are intraluminal papillae with hyaline cores similar to those seen in malignant endovascular papillary angioendothelioma (Dabska's tumor), but usually they are infrequent, focal and poorly developed. In our case, these papillary structures were well formed and distributed in a diffuse way. They were most conspicuous in superficial areas where the blood vessels were dilated. In deep areas, where the pattern of neoplastic vessels was retiform, the papillae filled their lumina totally, resembling solid cords. Our case shares the clinical and morphologic features of both retiform hemangioendothelioma and Dabska's tumor, supporting a relationship between these two kinds of neoplasms. The benign behavior of this case, with no recurrence or metastases over a 4-year follow-up, corresponds to the low malignancy of this kind of vascular neoplasm.

[Hemangiopericytoma of the renal sinus. Report of a case and review of the literature]. / Hemangiopericitoma del seno renal. A propósito de un caso y revisión de la literatura.

OBJECTIVES: Since the initial report of renal hemangiopericytoma by Black and Heinemann in 1955, only 24 cases of this rare vascular neoplasm, involving the renal capsule, parenchyma or sinus have been described in the world literature. Herein we describe an additional case and review the literature. METHODS: We report on a 65-old woman in whom a 5 x 4 cm solid mass was incidentally found in the left sinus. The tumor compressed the renal pelvis and caused hydronephrosis and parenchymal atrophy. A radical left nephrectomy was performed. Histological and immunological studies revealed a hemangiopericytoma of renal sinus soft tissues. RESULTS: The patient did well postoperatively and remains disease-free at the present time. CONCLUSIONS: Although there are other histological and clinical criteria indicative of worse prognosis, the malignancy of hemangiopericytoma is determined by the presence of hematogenous metastases.

Lepra lepromatosa de evolucion mortal

Se presenta el caso de un enfermos LL de 68 años de edad, intensamente positivo dianosticado hace 2 meses, que ingresa con un cuadro con lesiones úlcero-necróticas que afetan un 50% del tegumento, mal estado general y anemia. No obstante el tratamiento específico, corticoterapia y hemoterapia fallece a los 20 días.

Lepra dimorfa reaccional

Se presenta un caso de lepra dimorfa en un varón de 13 años, con múltiples lesiones cutáneas, placas, nódulos, pápilas, alopecia y neuropatía periférica. Bacilospopía positiva. Se le clasifica com BT con "downgrading reaction". A los 3 años del control persisten escasas lesiones, la bacteriología es negativa. Se hacen consideraciones sobre la inestabilidad y la frecuente evolúción sin terapéutica adecuada hacia el polo lepromatoso.

[Malignant rhabdoid tumor of the kidney: 2 cases and a review of the literature]. / Tumor rabdoide maligno renal: presentación de dos casos y revisión de la literatura.

Report of the microscopic, ultrastructural and immunohistochemical findings of two malignant rhabdoid tumors of the kidney in two males aged 2 1/2 and 19 months. The incidence of this tumor in our files is 1.9% of all the renal tumors of infancy. Both cases were formally considered to be rhabdomyosarcomatous variants of nephroblastomas. Microscopically a slightly cohesive polygonal cell proliferation is shown. The cells have intracytoplasmatic hyaline inclusions ultrastructurally identifiable as intermediate filament bundles, showing positivity to vimentin in the immunohistochemical technique. Malignant rhabdoid tumors are referred to as very aggressive tumors with a poor response to treatment and a high mortality rate. Association with central nervous tumors and hypercalcemia has been reported. The clinical and pathologic features make it possible to differentiate them from nephroblastomas, although the histogenesis is not definitely established.

Sarna noruega

Presentamos un caso de sarna noruega en una enferma con artritis reumatóide y sometida a corticoterapia general. Comentamos las principales características clínicas, etio-patogénicas, histopatológicas y terapéuticas de esta rara entidad.