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1.
Q J Exp Psychol (Hove) ; 73(5): 664-675, 2020 May.
Artigo em Inglês | MEDLINE | ID: mdl-31713472

RESUMO

Despite the centrality of the protagonist during narrative comprehension, evidence indicates that readers do not typically approach the text from the protagonist's point of view. Experiments 1a-1c demonstrated that both explicit task instructions and the first-person point of view resulted in comprehension being influenced by perspective-relevant information; this indicated that readers were adopting the perspective of the protagonist. However, Experiments 2a-3b showed that even when readers adopt the protagonist's perspective, they cannot do so to the exclusion of related perspective-irrelevant information. Results are discussed in the context of the RI-Val model of comprehension in which perspective-relevant information and perspective-irrelevant information are both available and compete for influence during comprehension.


Assuntos
Compreensão/fisiologia , Leitura , Teoria da Mente/fisiologia , Adulto , Feminino , Humanos , Masculino , Adulto Jovem
2.
Vision (Basel) ; 3(3)2019 Sep 06.
Artigo em Inglês | MEDLINE | ID: mdl-31735846

RESUMO

The majority of eye tracking studies in reading are on issues dealing with word level or sentence level comprehension. By comparison, relatively few eye tracking studies of reading examine questions related to higher level comprehension in processing of longer texts. We present data from an eye tracking study of anaphor resolution in order to examine specific issues related to this discourse phenomenon and to raise more general methodological and theoretical issues in eye tracking studies of discourse processing. This includes matters related to the design of materials as well as the interpretation of measures with regard to underlying comprehension processes. In addition, we provide several examples from eye tracking studies of discourse to demonstrate the kinds of questions that may be addressed with this methodology, particularly with respect to the temporality of processing in higher level comprehension and how such questions correspond to recent theoretical arguments in the field.

3.
Q J Exp Psychol (Hove) ; 72(5): 1055-1067, 2019 May.
Artigo em Inglês | MEDLINE | ID: mdl-29747551

RESUMO

Readers do not always adopt the perspective of the protagonist; however, they will under certain conditions. Experiments 1a and 1b showed that readers will take the perspective of the protagonist from the third-person point of view, but only when explicitly instructed to do so. Experiment 2 demonstrated that reading from the first-person point of view is a text-based manipulation that encourages readers to adopt the perspective of the protagonist. The results of Experiments 3a and 3b replicated the findings of Experiments 1a and 2. Experiment 4 established that simply increasing readers' attention to the text does not lead to adoption of the protagonist's perspective; moreover, this suggests that when it does occur, protagonist perspective adoption is not the result of increased attention, but strategic processing.


Assuntos
Atenção/fisiologia , Compreensão/fisiologia , Leitura , Teoria da Mente/fisiologia , Adulto , Feminino , Humanos , Masculino , Adulto Jovem
4.
Q J Exp Psychol (Hove) ; 71(11): 2282-2294, 2018 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-30362400

RESUMO

Fantasy-text is a genre in which events routinely violate rules we know to be true in the real world. In four experiments, we explored the inherent contradiction between unrealistic fictional events and general world knowledge (GWK) to examine these competing information sources within the context of an extended fantasy-narrative. Experiments 1a and 1b demonstrated that fantasy-unrelated inconsistencies caused disruption to comprehension despite an abundance of contextual support for real-world impossible events that violate GWK. Experiment 2a demonstrated that fantasy-related inconsistencies caused disruption when they occurred at the local level and the fantasy-context stood in direct opposition to the target sentence. However, Experiment 2b demonstrated that disruption can be initially eliminated when readers encountered fantasy-related violations at the global level, but delayed-processing difficulty occurred on the spillover sentence, downstream of the target sentence. All four experiments are discussed within the context of the RI-Val model.


Assuntos
Compreensão , Formação de Conceito/fisiologia , Fantasia , Narração , Adolescente , Análise de Variância , Feminino , Humanos , Masculino , Desempenho Psicomotor , Tempo de Reação , Leitura , Fatores de Tempo , Adulto Jovem
5.
J Exp Psychol Learn Mem Cogn ; 44(9): 1414-1429, 2018 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-29672121

RESUMO

The RI-Val model of comprehension includes a validation process in which linkages formed by integration are matched against active memory. In five experiments, we investigated factors that influence validation. Reading times were measured on target sentences that contained either correct information or semantically related, but incorrect content. Experiment 1 demonstrated that strong contextual support for shared features between correct and incorrect terms delayed processing difficulty associated with incorrect information. Experiment 2 confirmed that contextual information needed to be available in memory in order to influence validation. Experiments 3a and 3b showed that strong contextual support for distinguishing features between correct and incorrect terms led to immediate processing difficulty associated with incorrect information, whereas features-in-common led to delayed difficulty. Experiments 4 and 5 showed that the timing of validation effects is sensitive to subtle changes in task demands. The combined results are consistent with the assumptions of the RI-Val model. (PsycINFO Database Record


Assuntos
Compreensão , Ilusões , Memória , Semântica , Humanos , Modelos Psicológicos , Leitura
6.
J Craniofac Surg ; 28(5): 1297-1301, 2017 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-28582288

RESUMO

AIM: Ocular prostheses are integral for anophthalmic patients. Part 1 of this study reported that patients' aetiology, opinions, and attitudes significantly affected their prosthetic eyes experience. Part 2 investigates the patient satisfaction and acceptance in light of some of the aetiological demographics reported in Part 1. METHODOLOGY: One hundred sixty questionnaires were delivered to anophthalmic patients attending oculoplastic clinic. Etiological aspects presented in the questionnaire were disseminated in part 1. Patient satisfaction was assessed through 8 closed-end statements reflecting aspects concerning patient's views on prosthesis comfort and appearance; patient's expectations, self-esteem, and perception; and cooperation with ocularist. Each statement had 3 categories as agree, moderately agree, and disagree. A total of 126 questionnaires were returned (response rate was 78.8%). Data was analyzed using SPSS software. Association coefficients and correlations between variables were also analyzed. RESULTS: Total number of responses for the 8 statements was 888, averaging of 111 (expected 126) respondent per statement. Overall, 95.4% of our patients agreed with all satisfaction statements presented echoing very high satisfaction rate with their ocular prosthetics. Having an eye replacement that covers the defect is associated with high satisfaction among patients regardless of ocular prosthetic type. Patient acceptance of prosthesis in relation to employment status was high but not the same among the different categories (P > 0.05). High satisfaction with ocular prosthetics was prevalent among both genders, but there were no statistically significant differences in percentages of agreement in all statements (P > 0.05). Satisfaction and acceptance with ocular prosthetics was the same among all age groups of 12 to 85 years old (P > 0.05). CONCLUSIONS: The patient satisfaction is associated with the interplay of different variables that is related to ocular prosthesis design and its ability to disguise disfigurement (ie, prosthesis shape, resemblance to existing contra-lateral eye, etc.); patients themselves (ie, gender, age, occupation, marital status, etc); and psychological well-being and social support provided. Anophthalmic patients of the north west of England are significantly happy with their ocular prosthetic rehabilitation and support they receive from their regional hospital. Ocular prosthetics enhances their psychological well-being and social interaction and factors like patients' sex, age, employment status, and type of ocular prosthesis have no effect on their acceptance and satisfaction.


Assuntos
Anoftalmia/reabilitação , Olho Artificial , Satisfação do Paciente , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Criança , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Inquéritos e Questionários , Reino Unido , Adulto Jovem
7.
J Craniofac Surg ; 28(5): 1293-1296, 2017 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-28145922

RESUMO

PURPOSE: Ocular prostheses are constructed to aid cosmetic, functional, and psychological rehabilitation of anophthalmic patients. Part-1 of this study aimed to evaluate anophthalmic patients' opinions, attitudes, and experience about aspects related to their postfit ocular prostheses. METHODS: One hundred sixty questionnaires were delivered to anophthalmic patients inquiring about different information such as age, gender, occupation, eye-loss cause, prosthesis type, prosthesis-wearing frequency, prosthesis-cleaning frequency, and problems encountered. A total of 126 questionnaires were returned (response rate was 78.8%). Data was analyzed using SPSS software (P <0.05). RESULTS: The patients were 74 males and 52 females (57.55 years ±â€Š17.57). Almost 50% of the patients lost their eye due to trauma that was the highest among other causes (P <0.05). High proportion clean their prosthesis daily (37.4%) which was the highest among other cleaning regimes (P <0.05). Almost 30.3% experienced having problems with their prosthetic eye. Patients who clean their prosthetic eye every 6 months have experienced more problems (P <0.05). Majority of patients wear their prosthetic eyes 24 hours (92%) (P <0.05). Half of patients who received a prosthetic eye for the first time experienced problems with it (P <0.05) such as excess discharge (45%), infection (25%), and soreness (20%). However, the problems were independent of prosthesis-type (P >0.05). CONCLUSIONS: Trauma is the most common cause of anophthalmic patients in the North-West of England. Anophthalmic patients are likely to experience problems with their prosthetic eye if they have lost their natural eye due to disease; it is their first prosthesis; or if they clean it once every 6 months.


Assuntos
Anoftalmia/etiologia , Anoftalmia/reabilitação , Olho Artificial/estatística & dados numéricos , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Anoftalmia/epidemiologia , Criança , Traumatismos Oculares/complicações , Traumatismos Oculares/epidemiologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Inquéritos e Questionários , Reino Unido/epidemiologia , Adulto Jovem
8.
Q J Exp Psychol (Hove) ; : 1-11, 2016 Dec 09.
Artigo em Inglês | MEDLINE | ID: mdl-27882856

RESUMO

Several theorists have argued that readers fail to detect semantic anomalies during reading, and that these effects are indicative of "shallow processing" behaviours. Previous studies of semantic anomalies such as the Moses illusion have focused primarily on explicit detection tasks. In the present study, we examined participants' eye movements as they read true/false statements that were non-anomalous, or contained a semantic anomaly that was either high- or low-related to the correct information. Analyses of reading behaviours revealed that only low-related detected anomalies resulted in initial processing difficulty, but both detected and undetected anomalies, regardless of whether they were high- or low-related, resulted in delayed processing difficulty. The results extend previous findings on semantic anomalies and are discussed in terms of the RI-Val model of text processing.

9.
Mem Cognit ; 42(7): 1171-85, 2014 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-24796775

RESUMO

Previous researchers have demonstrated that readers may engage in shallow, or incomplete, processing when the semantic overlap between current information and previously encountered information is high. The present study investigated whether these effects would occur during processing of unambiguous noun phrase anaphors, for which there was only a single possible antecedent. Participants read passages containing anaphors that were correct, incorrect but highly related, or incorrect and low-related, with respect to previously encountered information. The time required to process the anaphor was a function of the goodness of fit between the anaphor and the antecedent; anaphors that were incorrect but highly related to the antecedent were processed more quickly than those that were incorrect and low-related. This occurred regardless of the distance between the anaphor and the antecedent. However, reading times results from a spillover sentence indicated that readers subsequently validated the anaphor against the information in memory, resulting in continued processing difficulty for both the incorrect-high- and -low-related anaphor conditions. The results are consistent with a three-stage comprehension model in which information is activated, integrated on the basis of its goodness of fit with the contents of working memory, and then validated against information in long-term memory.


Assuntos
Compreensão/fisiologia , Memória de Longo Prazo/fisiologia , Leitura , Adulto , Humanos , Adulto Jovem
10.
Mem Cognit ; 41(8): 1172-84, 2013 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-23702917

RESUMO

In this study, we examined two issues regarding the role of context in ambiguity resolution: whether access to the contextually appropriate meaning is exhaustive or selective, and whether the contextually inappropriate meaning is inhibited. Participants read texts in which a biased ambiguous word was encountered twice while their eye movements were measured. The context preceding the first encounter varied in the extent to which the subordinate meaning was supported; the context preceding the second encounter always supported the dominant meaning. The findings suggest that lexical access is exhaustive but can be influenced by context, and that the subsequent accessibility of the contextually inappropriate meaning is unaffected by previous selection processes. The results were interpreted in terms of the assumptions of the reordered-access model and activation mechanisms that operate during reading.


Assuntos
Movimentos Oculares/fisiologia , Psicolinguística/métodos , Leitura , Adulto , Medições dos Movimentos Oculares/instrumentação , Humanos , Psicolinguística/instrumentação , Distribuição Aleatória , Adulto Jovem
11.
Child Abuse Negl ; 36(7-8): 564-71, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-22858063

RESUMO

OBJECTIVE: Researchers in the child maltreatment field have traditionally relied on explicit self-reports to study factors that may exacerbate physical child abuse risk. The current investigation evaluated an implicit analog task utilizing eye tracking technology to assess both parental attributions of child misbehavior and empathy. METHOD: Based on the observation that readers experience comprehension difficulty when encountering passages inconsistent with their beliefs, an eye tracker gauged the extent of difficulty parents experienced reading vignettes that inappropriately characterized a child as culpable for misbehavior and that presented a non-empathic child interaction. RESULTS: Results suggest self-reports of attributions and empathy are related to both child abuse potential and discipline intentions; however, the eye tracking analog for empathy correlated with abuse potential but not punishment decisions whereas the analog for attributions correlated with punishment decisions but not abuse potential. CONCLUSIONS: Such contrasts between self-report and analog assessment underscore the need for continued research studying theorized abuse risk constructs using alternative approaches to better identify the important risk markers associated with elevated child abuse risk and to minimize methodological overlap.


Assuntos
Maus-Tratos Infantis/psicologia , Empatia , Pais/psicologia , Autorrelato , Adulto , Atitude Frente a Saúde , Criança , Medições dos Movimentos Oculares , Movimentos Oculares , Feminino , Humanos , Masculino , Punição/psicologia , Leitura , Medição de Risco
12.
J Exp Psychol Appl ; 18(3): 301-13, 2012 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-22545928

RESUMO

Our goal was to evaluate an alternative to current methods for detecting deception in security screening contexts. We evaluated a new cognitive-based test of deception that measured participants' ocular-motor responses (pupil responses and reading behaviors) while they read and responded to statements on a computerized questionnaire. In Experiment 1, participants from a university community were randomly assigned to either a "guilty" group that committed one of two mock crimes or an "innocent" group that only learned about the crime. Participants then reported for testing, where they completed the computer-administered questionnaire that addressed their possible involvement in the crimes. Experiment 2 also manipulated participants' incentive to pass the test and difficulty of statements on the test. In both experiments, guilty participants had increased pupil responses to statements answered deceptively; however, they spent less time fixating on, reading, and rereading those statements than statements answered truthfully. These ocular-motor measures were optimally weighted in a discrimination function that correctly classified 85% of participants as either guilty or innocent. Findings from Experiment 2 indicated that group discrimination was improved with greater incentives to pass the test and the use of statements with simple syntax. The present findings suggest that two cognitive processes are involved in deception-vigilance and strategy-and that these processes are reflected in different ocular-motor measures. The ocular-motor test reported here represents a new approach to detecting deception that may fill an important need in security screening contexts.


Assuntos
Enganação , Movimentos Oculares , Culpa , Detecção de Mentiras/psicologia , Adolescente , Crime/psicologia , Feminino , Humanos , Masculino , Pupila
13.
Br J Ophthalmol ; 95(10): 1389-92, 2011 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-21775766

RESUMO

AIMS: To evaluate the functional and cosmetic success rate of combined canalicular laceration and eyelid avulsion repairs using the bi-canalicular Crawford stent, without the concomitant placement of a medial traction suture to repair medial canthal tendon (posterior limb) avulsion. METHODS: Retrospective, non-comparative consecutive case series of 40 consecutive patients with traumatic eyelid avulsion injuries associated with canalicular laceration from 1997 to 2003 who underwent surgical repair using the bi-canalicular Crawford stent were included. All patients underwent surgical repair of the canalicular laceration under general anaesthesia using the bi-canalicular stent. Meticulous anastomosis of the torn canaliculus was undertaken. No attempt was made to suture the avulsed medial canthal tendon (posterior limb) to the periosteum of the posterior lacrimal crest. RESULTS: Blunt trauma was the most common mechanism of injury and the inferior canaliculus was most commonly involved. Of the 37 patients who attended postoperative follow-up, 24 patients had no subjective symptoms of epiphora. Minimal, mild and moderate epiphora was present in seven, five and one patient respectively. Thirty-three patients had excellent cosmetic repositioning of the lid; two developed medial ectropia and a further two patients had lid margin notching but good lid position. Eight patients had premature stent loss. CONCLUSIONS: Bi-canalicular stenting achieved excellent cosmetic results in eyelid avulsion injuries, by facilitating adequate tissue realignment without the need for a posterior lacrimal crest fixation suture. Good functional results were achieved and were comparable with previous studies.


Assuntos
Traumatismos Oculares/cirurgia , Pálpebras/lesões , Aparelho Lacrimal/lesões , Procedimentos de Cirurgia Plástica , Silicones , Stents , Adolescente , Adulto , Criança , Pré-Escolar , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Técnicas de Sutura , Tendões/cirurgia , Adulto Jovem
14.
J Exp Psychol Learn Mem Cogn ; 36(4): 979-91, 2010 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-20565213

RESUMO

In 2 previous studies (O'Brien, Rizzella, Albrecht, & Halleran, 1998; Zwaan & Madden, 2004), researchers have provided conflicting accounts about whether outdated information continues to influence the comprehension of subsequent text. The current set of experiments was designed to explore further the impact of outdated information on comprehension. First, we examined factors that may have contributed to Zwaan and Madden's (2004) finding that outdated information did not influence comprehension. Experiments 1a and 1b demonstrated that when Zwaan and Madden's target sentences were rewritten to move the targeted anaphor away from the end of the sentence, the impact of outdated information emerged with their materials. With a new set of materials, Experiment 2 demonstrated that outdated information continued to disrupt comprehension, even when the updating information created an irreversible change-in-state of a primary object in the story. The results of all 3 experiments are consistent with a passive reactivation process in which outdated information can influence comprehension processes.


Assuntos
Compreensão/fisiologia , Memória/fisiologia , Processos Mentais/fisiologia , Humanos , Narração , Leitura , Semântica , Estudantes , Universidades
15.
Clin Exp Ophthalmol ; 38(7): 688-91, 2010 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-20456439

RESUMO

BACKGROUND: Botulinum toxin (BTX) is the first-line treatment in managing benign essential blepharospasm (BEB) and hemifacial spasm (HFS). We wished to assess the difference in duration of effect and the number of BTX treatments required to treat patients with BEB and HFS. METHODS: A prospective study of patients attending the BTX clinic in Manchester Royal Eye Hospital over 6 months. All treatments were administered by a single experienced ophthalmologist. A questionnaire was completed for each patient. In patients with BEB where the BTX was injected bilaterally, one side was randomized to compare with HFS patients. Patient demographics, cumulative dose of BTX, duration of BTX effect with patient satisfaction and the number of previous BTX injections were recorded. RESULTS: Sixty-four patients were included in the study. The mean age was 60.8 years. Among them, 30 patients had BEB and 34 had HFS. Patients with HFS received a lower mean dose of BTX than patients with BEB (12.23 units vs. 16.2 units). The patients with HFS had a longer duration of effect than patients with BEB, with fewer BTX treatments. Of all patients, 90% with HFS and BEB were satisfied with the effect of their last BTX injection. Three unsatisfied patients in the BEB group were referred on for surgical management of their disorder. CONCLUSIONS: We have shown that patients with BEB have a shorter duration of effect with BTX and require more frequent BTX treatments than patients with HFS, highlighting that facial dystonias in patients with BEB is more challenging to manage.


Assuntos
Blefarospasmo/tratamento farmacológico , Toxinas Botulínicas Tipo A/administração & dosagem , Espasmo Hemifacial/tratamento farmacológico , Fármacos Neuromusculares/administração & dosagem , Adulto , Idoso , Idoso de 80 Anos ou mais , Toxinas Botulínicas Tipo A/efeitos adversos , Feminino , Humanos , Injeções Intradérmicas , Masculino , Pessoa de Meia-Idade , Fármacos Neuromusculares/efeitos adversos , Estudos Prospectivos , Inquéritos e Questionários
16.
J Med Case Rep ; 1: 179, 2007 Dec 14.
Artigo em Inglês | MEDLINE | ID: mdl-18081929

RESUMO

INTRODUCTION: Enophthalmos is an important physical sign which can be easily missed. CASE PRESENTATION: A 64-year old female presented with painless and progressive shrinking of her right eye. Visual acuity was 6/6 in both eyes. The main clinical findings included exophthalmometry readings of 14 mm in the right eye and 22 mm in the left eye and a linear scar on her right forehead. This scar is a feature of linear scleroderma and called "en coup de sabre". She was referred to a dermatologist for further assessment. CONCLUSION: Enophthalmos is defined as the relative recession of the globe into the bony orbit and if measuring greater than 2 mm can give a noticeable cosmetic deformity. Scleroderma is a systemic or localised disease. Linear scleroderma has the following features-localised fibrosis of the skin, blood vessels, subcutaneous fat, muscle and sometimes bone. Histology shows an inflammatory and a sclerotic phase. Ophthalmic effects include enophthalmos, lash loss, lid induration or tightening and periorbital oedema.

17.
Autism ; 11(3): 265-77, 2007 May.
Artigo em Inglês | MEDLINE | ID: mdl-17478579

RESUMO

Recent eye tracking studies of face processing have produced differing accounts of how and whether children with autism differ from their typically developing peers. The two groups' gaze patterns appear to differ for dynamic videos of social scenes, but not for static photos of isolated individuals. The present study replicated and extended previous research by comparing the gaze patterns of individuals with and without autism for four types of stimuli: social dynamic, social static, isolated dynamic, and isolated static. Participants with autism differed from their typically developing peers only for social-dynamic stimuli; fixation durations were decreased for eye regions and increased for body regions. Further, these fixation durations predicted scores on a measure of social responsiveness. These findings reconcile differences in previous reports by identifying the specific social and dynamic task components associated with autism-related face processing impairments.


Assuntos
Transtorno Autístico/epidemiologia , Face , Expressão Facial , Transtornos da Percepção/epidemiologia , Percepção Visual , Adolescente , Criança , Feminino , Fixação Ocular , Humanos , Masculino , Transtornos da Percepção/diagnóstico , Índice de Gravidade de Doença , Fatores de Tempo
18.
Br J Psychol ; 97(Pt 4): 467-82, 2006 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-17018184

RESUMO

Sentences containing lexically ambiguous words were read as readers' eye movements were monitored. On half of the trials, the dominant meaning of the ambiguous word was instantiated, while in the other half, the subordinate meaning was instantiated. Furthermore, on half of the trials, an adjective or modifier immediately preceded the target noun (kitchen table, statistical table), which was consistent with either the dominant or subordinate meaning. The results of the experiment demonstrate that readers are able to immediately utilize the modifier to select the appropriate meaning of the ambiguous word.


Assuntos
Compreensão , Movimentos Oculares , Tempo de Reação , Leitura , Semântica , Fixação Ocular , Humanos , Probabilidade
19.
Ophthalmic Plast Reconstr Surg ; 22(4): 259-65, 2006.
Artigo em Inglês | MEDLINE | ID: mdl-16855496

RESUMO

PURPOSE: To review patients with basal cell nevus syndrome (BCNS), documenting presentation, referrals, treatment patterns, and associated morbidity. METHODS: Cross-sectional review and retrospective data collection of 39 patients with BCNS. Patients from the BCNS support group were invited to be examined. Demographics, presenting features, associated pathologies, and treatment modalities were recorded. Demographic data, age at presentation, age at diagnosis, spectrum of ophthalmic and periocular disease, treatment modalities used, and periocular deformities developed were reviewed. RESULTS: Thirty-nine patients were included with age range of 5 to 72 years. Presenting clinical features included odontogenic keratocyst in 17 patients and basal cell carcinoma in 13 patients; less common presentations were with congenital malformations (n = 2), with ophthalmic associations (n = 3), and at genetic counseling (n = 4). Seventeen of the 39 patients confirmed a parental diagnosis of BCNS. Basal cell carcinoma developed in 18 of the 28 patients before the age of 30, confirming the reported early age of onset. Periocular basal cell carcinoma was reported in 24 of 39 patients (61%), with recurrent disease reported in 17 of these 24 (71%), despite a variety of treatment modalities used. Associated ophthalmic features were multiple eyelid cysts (15 patients), strabismus (9 patients), myopia (5 patients), hyperopia (7 patients), cataracts (5 patients), myelinated nerve fibers (3 patients), amblyopia (3 patients), and nystagmus and iris transillumination defects (2 patients each). All patients were involved in multidisciplinary medical care. CONCLUSIONS: Patients with BCNS frequently have ophthalmic manifestations, particularly periocular basal cell carcinoma. Multidisciplinary care is essential in the care of the patient with BCNS. Early diagnosis of BCNS may allow for skin protection and surveillance at an earlier age.


Assuntos
Síndrome do Nevo Basocelular/patologia , Adolescente , Adulto , Idoso , Carcinoma Basocelular/patologia , Criança , Pré-Escolar , Estudos Transversais , Oftalmopatias/diagnóstico , Neoplasias Palpebrais/patologia , Feminino , Aconselhamento Genético , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos
20.
Cognition ; 99(2): B53-62, 2006 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-16115615

RESUMO

An eye movement study of temporarily ambiguous closure sentences confirmed that the early closure penalty in a sentence like While John hunted the frightened deer escaped is larger for a simple past verb (hunted) than for a past progressive verb (was hunting). The results can be explained by the observation that simple past tense verbs convey an external viewpoint on an event, which presumably fits best when the event described has an endpoint. A definite description object supplies an endpoint. Consequently, to give up the late closure analysis of the post-verbal object when the verb is in the simple past tense, the processor is abandoning an analysis with semantically-expected properties for one which is not as good semantically. By contrast, a progressive verb denotes an activity which does not require an endpoint and therefore is neutral with respect to whether or not it takes an object.


Assuntos
Movimentos Oculares , Idioma , Semântica , Humanos
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