RESUMO
The association between acute pancreatitis and severe hypertriglyceridemia has long been recognized. We report two cases of severe primary hypertriglyceridemia (types 1 and V) with recurrent acute pancreatitis. In both patients, observance of appropriate diet and drug therapy was insufficient. Recurrent episodes of pancreatitis were precipitated by dietary fat or alcohol abuse. A plasmapheresis was performed every 4 weeks to decrease the incidence of pancreatitis. It appears that plasmapheresis is a safe and highly effective method for quickly removing serum triglycerides. Moreover, plasma-pheresis may be useful for preventing acute pancreatitis.
Assuntos
Hipertrigliceridemia/complicações , Hipertrigliceridemia/terapia , Pancreatite/prevenção & controle , Plasmaferese , Doença Aguda , Adulto , Colesterol/sangue , Feminino , Humanos , Hiperlipoproteinemia Tipo I/sangue , Hiperlipoproteinemia Tipo I/complicações , Hiperlipoproteinemia Tipo I/terapia , Hiperlipoproteinemia Tipo V/sangue , Hiperlipoproteinemia Tipo V/complicações , Hiperlipoproteinemia Tipo V/terapia , Masculino , Pancreatite/etiologia , Recidiva , Triglicerídeos/sangueRESUMO
The case of a woman suffering from urticaria of the colon is reported. The original endoscopic images were described and its allergic (corticotrophin) origin was documented through clinical arguments and in vivo and in vitro tests. The term acute allergic colitis seems to be more suitable taking into account the distribution, the cause and the development of this disease.
Assuntos
Hormônio Adrenocorticotrópico/efeitos adversos , Colite/induzido quimicamente , Hipersensibilidade a Drogas/etiologia , Doença Aguda , Adulto , Colonoscopia , Feminino , HumanosRESUMO
To estimate the renal glucose threshold, we measured glucosuria in 546 oral glucose tolerance tests (OGTT) (glucose oxidase method). The subjects, with normal renal function, presented during OGTT one or several peak plasma glucose levels between 10 and 13.4 mmol/l. The renal glucose threshold was thus higher than 10 mmol/l in the 43% of this population who were a glucosuric (normal renal threshold was between 8.8 and 10 mmol/l). The frequency of raised threshold was higher in obese patients than in subjects of normal body weight: indeed from 34% in non obese patients rates rose respectively at 37%, 50% and 68% in obesity groups (10 to 30%, 30 to 50% and 50% over ideal body weight (respectively). This trend was found regardless of the type of glucose tolerance response (ie. normal, IGT, non diagnostic, NIDD).
