[Clinico-pathological study of the effects of contraceptive treatment with mestranol-lynestrol by a sequential type method]. / Estudio clínico-patologico de los effectos de la terapia contraceptiva con mestranol-linestrol en una modalidad del tipo secuencial.

PIP: 100 healthy fertile women, with active sexual lives and of reproductive age, were treated during 10 cycles in 1 year with mestranol-lynestrenol of the sequential type, for the purpose of determining the effectiveness of the drug as a contraceptive and study its effects on endometrial morphology, endocervical mucus, cervicovaginal cytology and urinary excretion of pregnanediol. The changes in the menstrual cycle and side effects were observed. The results obtained clearly show that the combination of mestranol-lynestrenol is an effective contraceptive (no pregnancy occurred), safe and well tolerated, with minimal side effects.^ieng