Retinoblastoma y realce del nervio óptico en la resonancia magnética cerebral: ¿es siempre una metástasis? / Retinoblastoma and optic nerve enhancement in a brain magnetic resonance scan: is it always a metastasis?

CASO CLÍNICO: Niña con retinoblastoma unilateral que precisó tratamiento con quimioterapia intraarterial. En la resonancia magnética nuclear cerebral, realizada un mes después del tratamiento con quimioterapia intraarterial, se evidenció realce del nervio óptico (NO) poslaminar lo que hizo sospechar una infiltración tumoral del NO, por lo que se solicitaron exámenes adicionales donde se diagnosticó una probable neuropatía óptica. Discusión: Generalmente el realce del NO en la resonancia magnética nuclear cerebral en retinoblastoma corresponde a una invasión tumoral del NO; sin embargo, en la actualidad, se deben considerar otras alternativas diagnósticas asociadas al uso de nuevos tratamientos, como la quimioterapia intraarterial

CASE REPORT: The case is presented on a girl with a unilateral retinoblastoma that required treatment with intra-arterial chemotherapy. In the nuclear magnetic resonance imaging of the brain performed 1 month after intra-arterial chemotherapy treatment, post-laminar optic nerve (ON) enhancement was observed, leading to the suspicion of an ON tumour infiltration. Additional examinations were requested by which a probable optic neuropathy was diagnosed. DISCUSSION: The ON enhancement in magnetic resonance imaging of the brain in retinoblastoma generally corresponds to tumour invasion of the ON. However, other diagnostic alternatives associated with the use of new treatments, such as intra-arterial chemotherapy, should be considered

Retinoblastoma and optic nerve enhancement in a brain magnetic resonance scan: is it always a metastasis? / Retinoblastoma y realce del nervio óptico en la resonancia magnética cerebral: ¿es siempre una metástasis?

CASE REPORT: The case is presented on a girl with a unilateral retinoblastoma that required treatment with intra-arterial chemotherapy. In the nuclear magnetic resonance imaging of the brain performed 1 month after intra-arterial chemotherapy treatment, post-laminar optic nerve (ON) enhancement was observed, leading to the suspicion of an ON tumour infiltration. Additional examinations were requested by which a probable optic neuropathy was diagnosed. DISCUSSION: The ON enhancement in magnetic resonance imaging of the brain in retinoblastoma generally corresponds to tumour invasion of the ON. However, other diagnostic alternatives associated with the use of new treatments, such as intra-arterial chemotherapy, should be considered.