RESUMO
OBJECTIVE: To report a full-term newborn infant that developed a sepsis associated to meningitis caused by Neisseria meningitidis serogroup C on the 14th day of life. CASE DESCRIPTION: The patient was a term female infant, born to a mother with Systemic Lupus Erythematosus, with birth weight of 2,610 g, Apgar Score 1, 4 and 8, who needed mechanical ventilation for 24 hours. On the 7th day of life, the neonate was discharged from the hospital with good overall condition. On the 15th day of life, the newborn infant presented fever and respiratory failure. The cerebrospinal fluid showed 1042 cells/mm3, with neutrophilic predominance, protein of 435 mg/dL, and glucose < 10 mg/dL. The blood and the cerebrospinal fluid cultures were positive for Neisseria meningitidis serogroup C. The neonate was hospitalized, needing mechanical ventilation and vasoactive drugs, and received 21 days of crystalline penicillin. After hospital discharge, there were no signs of neurological sequels and the infant was able to be breastfed. The case report presents a unique situation: an uncommon etiology of neonatal meningitis and favorable evolution, despite neurological sequels reported in the literature. This report emphasizes the need to prevent the premature exposure of newborn infants to pathological agents, especially if they presented birth injuries and/or are preterm, due to their lack of immunological capacity.
Assuntos
Meningite Meningocócica/diagnóstico , Neisseria meningitidis Sorogrupo C/isolamento & purificação , Sepse/microbiologia , Feminino , Humanos , Recém-Nascido , Meningite Meningocócica/tratamento farmacológico , Penicilinas/uso terapêutico , Sepse/diagnóstico , Sepse/tratamento farmacológicoRESUMO
O texto apresenta uma revisão bibliográfica dos trabalhos publicados nos sobre o estado imunológico do recém-nascido prematuro e seus mecanismos de defesa antiinfecciosa. Arquivo em PDF. Requer o Adobe Acrobat Reader
Assuntos
Recém-Nascido , Recém-Nascido Prematuro , Doenças do Prematuro , InfecçõesRESUMO
During a measles outbreak, 2 mothers with measles gave birth at University Hospital in São Paulo City, Brazil. Blood, saliva and urine were collected from the mothers and newborns. Measles virus genome and IgM antibodies against measles were detected. In 1 infant, measles virus genome persisted in peripheral blood mononuclear cells for 157 days after birth.
