RESUMO
We have reported the case of a 69-year-old woman with a hugh benign fibrous tumor of the left pleura and hypoglycemic seizures. Increased preoperative levels of insulin-like growth factor (IGF II) were present; insulin level was low and plasma levels of somatomedin C were normal. After resection of the 2,400 gm tumor, blood sugar level has remained normal, and IGF II has fallen to normal limits. This appears to be the first reported case documenting elevated serum IGF II in association with a benign fibrous pleural tumor.
Assuntos
Carcinoma de Células Pequenas/patologia , Hipoglicemia/etiologia , Fator de Crescimento Insulin-Like II/análise , Neoplasias Pleurais/patologia , Somatomedinas/análise , Idoso , Carcinoma de Células Pequenas/sangue , Carcinoma de Células Pequenas/complicações , Carcinoma de Células Pequenas/diagnóstico por imagem , Carcinoma de Células Pequenas/cirurgia , Feminino , Humanos , Hipoglicemia/sangue , Neoplasias Pleurais/sangue , Neoplasias Pleurais/complicações , Neoplasias Pleurais/diagnóstico por imagem , Neoplasias Pleurais/cirurgia , Prognóstico , Síndrome , Tomografia Computadorizada por Raios XRESUMO
Deoxyribonucleic acid has been isolated from the microsomes of mouse liver homogenates under conditions designed to prevent or greatly reduce mitochondrial and nuclear contamination. The DNA rapidly incorporates tritiated thymidine, and this, together with its reannealing characteristics after thermal denaturation, shows that it is not mitochondrial or typically nuclear DNA.
