[Digestive involvement in dystrophic bullous epidermolysis. Presentation of 2 cases and review of the literature]. / Atteinte digestive au cours de l'épidermolyse bulleuse dystrophique. Présentation de deux cas et revue de la littérature.

Congenital epidermolysis bullosa is an inherited disorder characterized by an anomaly of joint structures between epidermis and dermis. This anomaly involves different malpighian epithelium and particularly in the digestive chorioepithelial junction. Digestive and oropharyngeal manifestations include bullae, erosions and ulcerations that heal by fibrosis, leading to retraction and stenosis. We report two cases of esophageal stenosis, the first one in a young patient with a congenital epidermolysis bullosa of Hallopeau-Siemens and the second one, in a young woman with a Pasini variant. In the first case, the esophageal stenosis was treated by careful dilation. In the second case, the endoscopy induced hemorragic bullae and septicemia, which were treated with antibiotics and total parenteral nutrition.

[Use of tiapride in internal medicine (author's transl)]. / Utilisation du tiapride en médecine interne.

Tiapride is tested about 47 in-patients among 6 morbid conditions studied. Tiapride is particulary effective in 4 diseases : delirium tremens, nervous and mental disordes associated with alcoholic addiction are obviously improbed in 2/3 of cases ; the betterment of motor and behaviour disordes concerning old people and the prevention of cephalagia succeding spinal puncture is sure with tiapride. The clinical and biological tolerance is excellent particulary in precarious patients.