1.
Mol Cell Oncol
; 5(5): e1023929, 2018.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30263930
RESUMO
Horizontal gene transfer is known to occur in bacteria and archaea whereas higher organisms including mammals undergo vertical transfer. Our recent results demonstrate horizontal transfer of mitochondrial DNA (mtDNA) from normal host cells to tumor cells lacking mitochondrial DNA (mtDNA). This mtDNA migration results in recovery of respiration, restored tumor initiation, and metastasis.