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1.
Radiat Environ Biophys ; 49(1): 87-95, 2010 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-19924427

RESUMO

A conceptual model of the effects of chronic radiation on a population of phytoplankton and zooplankton in an oceanic nutrient layer is presented. The model shows that there are distinct threshold dose rates at which the different plankton populations become unsustainable. These are 10,400 microGy h(-1) for phytoplankton and 125 microGy h(-1) for zooplankton. Both these values are considerably greater than the current screening values for protection of 10 microGy h(-1). The model highlights the effects of predator-prey dynamics in predicting that when the zooplankton is affected by the radiation dose, the phytoplankton population can increase. In addition, the model was altered to replicate the dose rates to the plankton of a previous ERICA Irish Sea assessment (24 microGy h(-1) for zooplankton and 430 microGy h(-1) to phytoplankton). The results showed only a 10% decrease in the zooplankton population and a 15% increase in the phytoplankton population. Therefore, at this level of dose, the model predicts that although the dose rate exceeds the guideline value, populations are not significantly affected. This result highlights the limitations of a single screening value for different groups of organisms.


Assuntos
Fitoplâncton/efeitos da radiação , Zooplâncton/efeitos da radiação , Animais , Relação Dose-Resposta à Radiação , Dose Letal Mediana , Modelos Biológicos , Doses de Radiação , Medição de Risco , Fatores de Tempo
2.
Radiat Environ Biophys ; 49(1): 67-85, 2010 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-19855992

RESUMO

The basic principles underlying a four-discrete age group, logistic, growth model for the European lobster Homarus gammarus are presented and discussed at proof-of-concept level. The model considers reproduction, removal by predation, natural death, fishing, radiation and migration. Non-stochastic effects of chronic low linear energy transfer (LET) radiation are modelled with emphasis on (99)Tc, using three endpoints: repairable radiation damage, impairment of reproductive ability and, at higher dose rates, mortality. An allometric approach for the calculation of LD(50/30) as a function of the mass of each life stage is used in model calibration. The model predicts that at a dose rate of 1 Gy day(-1), lobster population reproduction and survival become severely compromised, leading eventually to population extinction. At 0.01 Gy day(-1), the survival rate of an isolated population is reduced by 10%, mainly through loss of fecundity, comparable to natural migration losses. Fishing is the main ecological stress and only dose rates in the range 0.03-0.1 Gy day(-1) can achieve discernible effects above it. On the balance of radiation and other ecological stresses, a benchmark value of 0.01 Gy day(-1) is proposed for the protection of lobster populations. This value appears consistent with available information on radiation effects in wildlife.


Assuntos
Modelos Biológicos , Nephropidae/efeitos da radiação , Fatores Etários , Migração Animal , Animais , Relação Dose-Resposta à Radiação , Ecossistema , Monitoramento Ambiental , Feminino , Fertilidade/efeitos da radiação , Cinética , Masculino , Nephropidae/fisiologia , Doses de Radiação , Reprodução/efeitos da radiação , Medição de Risco , Fatores de Tempo
3.
Rapid Commun Mass Spectrom ; 21(18): 3093-102, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-17705255

RESUMO

A method to control the duty cycle of a time-of-flight mass spectrometer is described. The method relies on one or more ion gates placed in the beam path that have the function to transmit or stop the beam. These ion gates can switch from the open state to the closed state in tens of nanoseconds and effectively select portions of the mass range. The method is useful in circumstances where recording the complete mass spectrum is not an essential requirement, for example, in the analysis of known compounds where sensitivity and speed of operation are more important. It will be of benefit for applications in separation sciences with techniques involving fast chromatographic separations, where hundreds of mass spectra may be required per second. In such circumstances analytical identification may require only a limited number of masses (or mass regions) to be continuously monitored. Improvement of the duty cycle is particularly important for orthogonal-acceleration time-of-flight (oa-TOF) mass spectrometry instruments whose performance suffers from a low duty cycle. The duty cycle is not a constant for an instrument design but is a mass-dependent function and is least for smaller masses. The method described here is capable of raising the duty cycle to 100%. A theory is developed for one or more ion gate arrangements, for both linear- and reflectron-TOF systems. For a two-gate system the relationship between the positions of the first and second gates is described by a '2/3 rule'. Experimental results are shown for one-gate and two-gate operation, both in linear and in reflectron modes of operation, on an oa-TOF system built in-house.


Assuntos
Desenho Assistido por Computador , Espectrometria de Massas por Ionização por Electrospray/instrumentação , Espectrometria de Massas por Ionização por Electrospray/métodos , Desenho de Equipamento , Análise de Falha de Equipamento , Íons , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
4.
Child Care Health Dev ; 6(1): 17-24, 1980.
Artigo em Inglês | MEDLINE | ID: mdl-7363406

RESUMO

The present study was conducted in a small 20-bed hospital for severely subnormal children. Ten children who had evidenced a history of problem behaviour were the subjects of behaviour modification programmes aimed at reducing the frequency of problem behaviour. The main aim of the study was to establish if nursing assistants can become effective co-therapists. Two questions were investigated: (1) Can nursing assistants after 12 months' training have a sound knowledge of the principles of behaviour modification and (2) Can these nursing assistants effectively employ behaviour modification techniques which result in reductions of problem behaviour episodes? It is argued that although nursing assistants may have had an inadequate and erroneous knowledge of the principles of behaviour modification, they were able to employ behavioural techniques which affected reductions in the problem behaviours recorded. Clinical difficulties related to applied research of this kind are raised in discussion.


Assuntos
Terapia Comportamental/métodos , Transtornos do Comportamento Infantil/reabilitação , Assistentes de Enfermagem , Criança , Humanos , Deficiência Intelectual/reabilitação , Avaliação de Processos e Resultados em Cuidados de Saúde
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