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Radiat Res ; 160(4): 488-91, 2003 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-12968926

RESUMO

L929 murine fibroblast cells were exposed to radiofrequency (RF) radiation from a time division multiple access wireless phone operating at 835 MHz frequency to determine the effect of RF-radiation energy emitted by wireless phones on ornithine decarboxylase (ODC) activity in cultured cells. Exposure was for 8 h to an average specific absorption rate (SAR) from <1 W/kg up to 15 W/kg. After exposure, cells were harvested and ODC activity was measured. No statistically significant difference in ODC activity was found between RF-radiation-exposed and sham-exposed cells at non-thermal specific absorption rates. At SARs which resulted in measurable heating of the medium, a dose-dependent decrease in enzymatic activity was observed and was shown to be consistent with a comparable decrease caused by non-RF-radiation heating. Thus we observed only the well-known enzyme inhibition due to heating, rather than the previously reported enhancement attributed to RF-radiation exposure.


Assuntos
Ativação Enzimática/efeitos da radiação , Fibroblastos/enzimologia , Fibroblastos/efeitos da radiação , Temperatura Alta , Ornitina Descarboxilase/biossíntese , Ornitina Descarboxilase/efeitos da radiação , Ondas de Rádio , Animais , Contagem de Células , Linhagem Celular , Relação Dose-Resposta à Radiação , Camundongos , Valores de Referência
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