Assuntos
Carcinoma de Células Escamosas/diagnóstico por imagem , Neoplasias da Túnica Conjuntiva/diagnóstico por imagem , Neoplasias de Cabeça e Pescoço/diagnóstico por imagem , Neoplasias Primárias Múltiplas/diagnóstico por imagem , Neoplasias Orbitárias/diagnóstico por imagem , Síndrome da Imunodeficiência Adquirida/complicações , Carcinoma de Células Escamosas/complicações , Carcinoma de Células Escamosas/patologia , Neoplasias da Túnica Conjuntiva/complicações , Neoplasias da Túnica Conjuntiva/patologia , Neoplasias de Cabeça e Pescoço/complicações , Neoplasias de Cabeça e Pescoço/patologia , Humanos , Masculino , Pessoa de Meia-Idade , Invasividade Neoplásica , Neoplasias Primárias Múltiplas/complicações , Neoplasias Primárias Múltiplas/patologia , Neoplasias Orbitárias/complicações , Neoplasias Orbitárias/patologia , Índice de Gravidade de Doença , Carcinoma de Células Escamosas de Cabeça e Pescoço , Tomografia Computadorizada por Raios XRESUMO
Liposarcomas are malignant soft tissue neoplasms usually located in the retroperitoneum, head, neck and extremities. Although secondary invasion of the gastrointestinal tract by retroperitoneal sarcomas is frequent, primary involvement is uncommon. We report a young patient with Crohns disease in remission presenting with intussusception of the colon due to a primary liposarcoma of the sigmoid. Emergency resection confirmed the diagnosis. The patient remains in remission after five years. This represents the youngest diagnosis of liposarcoma to date and the first occurring in the sigmoid. We also highlight the concomitant diagnosis of Crohn´s disease (AU)
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Assuntos
Humanos , Feminino , Adulto , Lipossarcoma/patologia , Neoplasias do Colo Sigmoide/patologia , Neoplasias de Tecidos Moles/patologia , Intussuscepção/etiologia , Doença de Crohn/complicaçõesRESUMO
Liposarcomas are malignant soft tissue neoplasms usually located in the retroperitoneum, head, neck and extremities. Although secondary invasion of the gastrointestinal tract by retroperitoneal sarcomas is frequent, primary involvement is uncommon. We report a young patient with Crohn's disease in remission presenting with intussusception of the colon due to a primary liposarcoma of the sigmoid. Emergency resection confirmed the diagnosis. The patient remains in remission after five years. This represents the youngest diagnosis of liposarcoma to date and the first occurring in the sigmoid. We also highlight the concomitant diagnosis of Crohn´s disease.
Assuntos
Doenças do Colo/diagnóstico , Intussuscepção/diagnóstico , Lipossarcoma/diagnóstico , Neoplasias do Colo Sigmoide/diagnóstico , Adulto , Doenças do Colo/etiologia , Doença de Crohn/complicações , Feminino , Humanos , Intussuscepção/etiologia , Lipossarcoma/complicações , Lipossarcoma/cirurgia , Neoplasias do Colo Sigmoide/complicações , Neoplasias do Colo Sigmoide/cirurgia , Tomografia Computadorizada por Raios XRESUMO
Protein-losing gastropathy is a rare entity. Unlike the disease in adults, it usually is benign and self-limited in children. The aetiological contribution of cytomegalovirus has been insufficiently documented and the immunological status of patients was rarely described in most reports. The authors report an 11-year-old boy with generalised oedema and hypoproteinemia. Upper endoscopy with biopsies showed marked hypertrophy of gastric folds and foveolar hyperplasia involving the body and fundus. The presence of cytomegalovirus in gastric tissue was well documented through identification of intranuclear inclusions, immunohistochemistry and PCR. Immunodeficiency was clearly ruled out. Protein-losing gastropathy should be considered in children with oedema and hypoproteinemia. The aetiological diagnosis should be confirmed by endoscopy-based methods.
Assuntos
Infecções por Citomegalovirus/complicações , Enteropatias Perdedoras de Proteínas/complicações , Gastropatias/complicações , Estômago/patologia , Criança , Citomegalovirus/isolamento & purificação , Edema/etiologia , Humanos , Hipertrofia/patologia , Hipoproteinemia/etiologia , Masculino , Enteropatias Perdedoras de Proteínas/diagnóstico , Enteropatias Perdedoras de Proteínas/terapia , Estômago/diagnóstico por imagem , Estômago/virologia , Gastropatias/patologia , Gastropatias/terapia , UltrassonografiaRESUMO
INTRODUCTION: Conjunctival melanoma is a relatively rare ocular malignancy with substantial associated morbidity and mortality. It can arise in previously unblemished and unpigmented regions (approximately 10% of cases), from a preexisting nevus (approximately 20% of cases), or from the flat, spreading pigmentation of primary acquired melanosis with atypia (60-70% of cases), actually called conjunctival melanocytic intraepithelial neoplasia (C-MIN) with atypia (histopathologically more accurately term). PURPOSE: The authors describe an extremely rare case of malignant conjunctival melanoma, with a long evolution, in a young black woman. RESULTS: Until now the patient has not shown any sign of relapse of this melanoma, after local excision. CONCLUSION: Conjunctival melanoma is a condition of concern because of its rarity and lethal potential. Advances in the understanding and management of this neoplasm have markedly reduced the mortality and possibly the morbidity associated with this malignancy. We observe that there are some cases of conjunctival melanoma that might be cured with only a local excision with posterior cryotherapy without more aggressive methods. The practice of narrative medicine brings new possibilities in the diagnosis and collection of classical history.
RESUMO
PURPOSE: Mucoepidermoid carcinoma is a rare variant of squamous cell carcinoma of the conjunctiva. It appears more frequently in the elderly, it is more aggressive than squamous cell carcinoma, and it has a higher recurrence rate and higher incidence of intraocular and orbital invasion. METHODS: We report a case of a 74-year-old man who presented to the Emergency Department with a one month history of painful red left eye. RESULTS: The patient presented with visual acuity was 10/10 in both eyes and a conjunctiva tumor on the bulbar conjunctiva of left eye. The UBM revealed a thickening of the conjunctiva-sclera complex with no signs of intraocular invasion. A biopsy was performed and the diagnosis was of mucoepidermoid carcinoma. Two local excisions with adjuvant cryotherapy and mitomycin C aplication were carried out in a period of 6 months. After 9 months of follow-up there has not been any sign of recurrence. CONCLUSIONS: The early diagnosis and treatment of carcinoma is essential not only to prevent the intraocular spread and preserve visual function but also to prevent local or systemic recurrence and dissemination.