RESUMO
Introdução: A segurança do paciente é um dos principais alvos de estudo na atualidade, em diversos segmentos no âmbito da saúde. Os problemas relacionados a medicamentos (PRM) se destacam entre os mais cometidos nos serviços de saúde. A atuação do farmacêutico na farmácia clínica se institui como um serviço que contribui para a otimização dos cuidados hospitalares melhorando a qualidade da farmacoterapia, minimizando os problemas relacionados aos medicamentos. Objetivo: Identificar e quantificar os PRM e as intervenções farmacêuticas encontradas no serviço de Farmácia do Hospital Universitário da Universidade Federal de Juiz de Fora (HU-UFJF) e também apresentar as taxas de aceitação das intervenções farmacêuticas de acordo com a aceitabilidade da equipe de saúde. Material e Métodos: Foi feito um estudo retrospectivo observacional no HU-UFJF dos resultados obtidos pelo serviço de farmácia clínica no período de abril a outubro de 2018. Resultados: Foram avaliadas 18.795 prescrições, sendo encontrados e considerados 2.834 PRM, sendo o tipo de problema relacionado ao medicamento mais prevalente o de diluição e/ou taxa de infusão correspondendo a 28,7%. Houve uma boa aceitação por parte da equipe de saúde às intervenções propostas pelo farmacêutico. Conclusão: O serviço de farmácia clínica detectou vários problemas relacionados ao uso de medicamento, que levou a oportunidades de melhoria na farmacoterapia, contribuindo para a segurança do paciente.
Introduction: Patient safety is one of the main study targets today, in several segments in the health field. Drug-related problems (DRP) stand out among the most commonly committed in health services. The pharmacist's role in the clinical pharmacy is established as a service that contributes to the optimization of hospital care by improving the quality of pharmacotherapy, minimizing drug-related problems. Objective: To identify and quantify the DRP and pharmaceutical interventions found in the Pharmacy Service of the University Hospital of the Federal University of Juiz de Fora (HU-UFJF) and also present the acceptance rates of pharmaceutical interventions according to the acceptability of the health team. Material and Methods: A retrospective observational study was carried out at HU-UFJF of the results obtained by the clinical pharmacy service from April to October 2018. Results: 18.795 prescriptions were evaluated and 2.834 PRM were found and considered. The most prevalent type of drug-related problem was dilution and/or infusion rate corresponding to 28.7%. Conclusion: The clinical pharmacy service detected several problems related to drug use, which led to opportunities for improvement in pharmacotherapy, contributing to patient safety.
Assuntos
Farmácia , Assistência Farmacêutica , Equipe de Assistência ao Paciente , Preparações Farmacêuticas , Prescrições , Segurança do Paciente , Erros de MedicaçãoRESUMO
Enteric viruses are present in aquatic environments due to contamination by raw sewage, even in the absence of fecal coliforms, which are considered to be significant indicators when it comes to microbial water quality assessment. This study investigated the presence of group A rotavirus (RVA) in surface water from a river basin in Minas Gerais, Brazil, assessing the influence of the urbanization, the rainfall, and the microbiological and physico-chemical parameters regarding water quality. Forty-eight surface water samples collected in urbanized and non-urbanized areas, both in dry and rainy periods, were obtained throughout the study. The viral particles were concentrated by adsorption-elution in a negatively charged membrane. Fecal coliforms, as well as physico-chemical water parameters were determined at each point in all collections. The RVA was detected in 62.5 % (30/48) of the water samples through a real-time PCR assay. All the sequenced RVA strains belonged to genotype I1. The RVA was detected in 50.0 % (11/22) of the water samples regarded as being acceptable by current microbiological standards. The presence of the RVA and the viral load were influenced by the collection area (p < 0.05). It was also observed a significant association between the RVA and detecting the turbidity of water (p < 0.05). The collected data showed a high level of contamination in this watershed by the discharge of raw sewage, highlighting the need for urgent measures to improve water quality, ensuring the safe use of this matrix.
