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1.
Brain Inj ; 38(1): 45-60, 2024 01 02.
Artigo em Inglês | MEDLINE | ID: mdl-38219070

RESUMO

OBJECTIVE: Evaluate the role of cognitive reserve (CR) on cognitive and physical sequelae in traumatic brain injury (TBI). METHODS: A comprehensive search strategy was conducted in four databases in English and Spanish in the last 12 years (2011-2023). Inclusion criteria: original cross-sectional and longitudinal studies whose main or secondary objective was to evaluate the effect of CR in adult patients with TBI. PRISMA guidelines were used to report the search and selection method and STROBE checklist was used to evaluate the quality of studies. RESULTS: Eighteen observational studies were included in this review. Multiple sources of variability were observed: number of patients, time of evolution, severity of the TBI, type of CR proxy, cognitive assessment instrument, etc. However, the most commonly used indicators of CR were premorbid IQ and educational attainment. A positive and consistent association between CR and performance on cognitive tests after injury was found. CONCLUSIONS: CR has a consistent positive effect on cognition and on some other aspects of recovery in traumatic brain injury. In future studies, it will be necessary to promote the use of CR indices based on various indicators and explore the effects of CR on other aspects related to the recovery of brain trauma.


Assuntos
Lesões Encefálicas Traumáticas , Lesões Encefálicas , Reserva Cognitiva , Adulto , Humanos , Estudos Transversais , Lesões Encefálicas Traumáticas/complicações , Lesões Encefálicas Traumáticas/psicologia , Lesões Encefálicas/complicações , Cognição
2.
Pharmaceuticals (Basel) ; 16(10)2023 Oct 05.
Artigo em Inglês | MEDLINE | ID: mdl-37895892

RESUMO

The kynurenine pathway (KP) and the endocannabinoid system (ECS) are known to be deregulated in depression and obesity; however, it has been recognized that acute physical exercise has an important modulating role inducing changes in the mobilization of their respective metabolites-endocannabinoids (eCBs) and kynurenines (KYNs)-which overlap at some points, acting as important antidepressant, anti-nociceptive, anti-inflammatory, and antioxidant biomarkers. Therefore, the aim of this review is to analyze and discuss some recently performed studies to investigate the potential interactions between both systems, particularly those related to exercise-derived endocannabinoidome and kynurenine mechanisms, and to elucidate how prescription of physical exercise could represent a new approach for the clinical management of these two conditions.

3.
Sci Total Environ ; 892: 164264, 2023 Sep 20.
Artigo em Inglês | MEDLINE | ID: mdl-37209730

RESUMO

Green infrastructure drainage systems are innovative treatment units that capture and treat stormwater. Unfortunately, highly polar contaminants remain challenging to remove in conventional biofilters. To overcome treatment limitations, we assessed the transport and removal of stormwater vehicle-related organic contaminants with persistent, mobile, and toxic (in short: PMTs) properties, such as 1H-benzotriazole, NN'-diphenylguanidine, and hexamethoxymethylmelamine (PMT precursor), using batch experiments and continuous-flow sand columns amended with pyrogenic carbonaceous materials, like granulated activated carbon (GAC) or wheat-straw derived biochar. Our results indicated that all investigated contaminants were subjected to nonequilibrium interactions in sand-only and geomedia-amended columns, with kinetic effects upon transport. Experimental breakthrough curves could be well described by a one-site kinetic transport model assuming saturation of sorption sites, which we inferred could occur due to dissolved organic matter fouling. Furthermore, from both batch and column experiments, we found that GAC could remove contaminants significantly better than biochar with higher sorption capacity and faster sorption kinetics. Hexamethoxymethylmelamine, with the lowest organic carbon-water partition coefficient (KOC) and largest molecular volume among target chemicals, exhibited the lowest affinity in both carbonaceous adsorbents based on estimated sorption parameters. Results suggest that sorption of investigated PMTs was likely driven by steric and hydrophobic effects, and coulombic and other weak intermolecular forces (e.g., London-van der Waals, H-bonding). Results from extrapolating our data to a 1-m depth geomedia-amended sand filter suggested that GAC and biochar could enhance the removal of organic contaminants in biofilters and last for more than one decade. Overall, our work is the first to study treatment alternatives for NN'-diphenylguanidine and hexamethoxymethylmelamine, and contributes to better PMT contaminant removal strategies in environmental applications.


Assuntos
Carvão Vegetal , Guanidinas , Carvão Vegetal/química , Adsorção
4.
J Nerv Ment Dis ; 211(8): 585-591, 2023 08 01.
Artigo em Inglês | MEDLINE | ID: mdl-37184446

RESUMO

ABSTRACT: Depression and anxiety are common complications after stroke and little is known about the modulatory roles of education and age. Our study aimed to evaluate the modulatory effects of education level on anxiety and depression after stroke and their effect on each age group. Adults with first stroke took part in this cross-sectional observational clinical study. We used the following instruments: Hospital Anxiety and Depression Scale (HADS), Montreal Cognitive Scale, Pittsburgh Sleep Quality Index, Barthel index, and Functional Independence Measure. There were 89 patients. The mean (SD) age was 58.01 (13) years, mean (SD) years of education was 9.91 (5.22), 55.1% presented depression symptoms and 47.2% anxiety symptoms, 56.2% were young adults and 43.8% were older adults. We identified a negative association between education and anxiety score ( r = -0. 269, p = 0.011) and depression score ( r = -0.252, p = 0.017). In the linear regression analysis, we found that education is negatively associated with HADS, but this influence was more consistent in young adults. In conclusion, a higher education level reduces the risk of depression and anxiety, but their effect is less consistent in older adults.


Assuntos
Depressão , Acidente Vascular Cerebral , Adulto Jovem , Humanos , Idoso , Pessoa de Meia-Idade , Depressão/epidemiologia , Depressão/etiologia , Depressão/diagnóstico , Estudos Transversais , Ansiedade/epidemiologia , Ansiedade/etiologia , Ansiedade/diagnóstico , Acidente Vascular Cerebral/complicações , Escolaridade
5.
Behav Sci (Basel) ; 13(2)2023 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-36829349

RESUMO

Suicide is considered a public health problem that affects families worldwide. Family functioning is the capability of the family system to fulfill needs during the stages of its development. In this study, we focused on evaluating family cohesion and adaptability in a group of adolescents who had attempted suicide and were hospitalized at a hospital for mental health disorders, compared to a control group. Methods: based on Olson's circumplex model, we used the FACES III scale to gain insights into the family functioning of both suicidal and control groups. Results: The case group presented lower scores in cohesion and adaptability compared to the control group, with moderate effect-size for cohesion (Cohen's d/r test = 1.217/0.52) and low effect-size for adaptability (Cohen's d/r test = 0.746/0.35) (p < 0.001 for both variables), and also presented predominantly disengaged families (72.5% in the case group vs. 27.5% in the control group) and structured families (45% in the case group vs. 23.8% in the control group). The type of family described by the adolescents with a history of suicide attempts may explain the presence of low self-esteem and little emotional support usually present in this type of patient.

6.
Con-ciencia (La Paz) ; 8(2): 101-111, 2020. tab.
Artigo em Espanhol | LILACS, LIBOCS | ID: biblio-1148015

RESUMO

INTRODUCCIÓN: la miel, consumida por el hombre desde hace miles de años debido a sus propiedades organolépticas y terapéuticas, es el producto de la unión entre el mundo animal, la abeja (apis melífera), y el vegetal, el néctar de las flores y/o secreciones azucaradas de las plantas o insectos. En general existen diferencias significativas entre las características físico-químicas de las mieles florales y la miel de mielada. OBJETIVO: determinar del porcentaje de miel de flores y miel de mielada comercializadas en supermercados de la ciudad de La Paz. MÉTODOS: Para la diferenciación entre miel de flores y miel de mielada se utilizó el método estandarizado por el Centro de Investigaciones Apícolas ­ CEDIA) y para la determinación de los parámetros fisicoquímicos, los métodos establecidos en la Norma Boliviana (NB 38023). RESULTADOS: Se analizaron 25 muestras de miel comercializadas en supermercados de la ciudad de La Paz, y a través del parámetro cualitativo de diferenciación de miel de flores y miel de mielada, se logró evidenciar que el 88,46% corresponde a mieles de origen floral, el 7,69 % a mieles de mielada y el 0,96 a mieles adulteradas. CONCLUSIONES: los datos obtenidos reflejan la importancia de considerar en el etiquetado el origen del que procede la miel, así mismo recomendar que este parámetro forme parte de los requisitos de la Norma Boliviana de Miel y de esta manera otorgar un mayor valor comercial a la miel de procedencia nacional.


INTRODUCTION: honey, consumed by man for thousands of years due to its organoleptic and therapeutic properties, is the product of the union between the animal world, the bee (Apis melífera), and the plant, the nectar of flowers and / or sugary secretions from plants or insects. In general, there are significant differences between the physicochemical characteristics of floral honeys and honeydew honey. OBJECTIVE: to determine the percentage of flower honey and honeydew honey sold in supermarkets in the City of La Paz. METHODS: for the differentiation between flower honey and honeydew honey, the standardized method by the Beekeeping Research Center - CEDIA) was used and for the determination of the physicochemical parameters, the methods established in the Bolivian Standard (NB 38023). RESULTS: 25 samples of honey sold in supermarkets in the city of La Paz were analyzed, and through the qualitative parameter of differentiation of flower honey and honeydew honey, it was possible to show that 88.46% corresponds to honeys of origin floral, 7.69% to honeydew honeys and 0.96 to adulterated honeys. CONCLUSIONS: the data obtained reflect the importance of considering the origin of the honey in the labeling, as well as recommending that this parameter be part of the requirements of the Bolivian Honey Standard and thus granting a greater commercial value to the honey of national origin.


Assuntos
Pesquisa , Flores , Criação de Abelhas , Mel , Plantas , Abelhas , Néctar de Plantas
7.
GEN ; 68(1): 3-7, mar. 2014. ilus, tab
Artigo em Espanhol | LILACS | ID: lil-740304

RESUMO

La curación mucosa endoscópica en enfermedad inflamatoria intestinal se asocia con remisión clínica sostenida, reducción de hospitalizaciones y cirugía, pero lograrlo es difícil, según la literatura. Por ello evaluamos la mejoría mucosa endoscópica en nuestros pacientes. Objetivo: Evaluar la mejoría mucosa endoscópica en pacientes con enfermedad inflamatoria intestinal. Métodos: estudio multicéntrico, descriptivo, transversal. Incluyó 24 pacientes entre 17 y 73 años. Para evaluar respuesta a tratamiento se realizó colonoscopia, utilizando clasificaciones endoscópicas de Mayo para colitis ulcerosa, Score simplificado para enfermedad de Crohn y Rutgeerts para recurrencia post operatoria, considerando curación endoscópica grado 0 en todas las escalas y mejoría cuando disminuyó un grado en relación al estudio previo. Resultados: colitis ulcerosa: 12 pacientes, 10 recibían aminosalicilatos y 2 terapia biológica. De ellos, 3 tuvieron curación endoscópica y 8 mejoría. De estos, 6 recibían aminosalicilatos y 2 Infliximab. Hubo 1 paciente con aminosalicilatos sin mejoría. Enfermedad de Crohn: 12 pacientes, 7 con aminosalicilatos, 2 con biológicos, 2 con biológicos e inmunomoduladores y 1 con biológicos y aminosalicilatos. De ellos, 4 tuvieron mejoría, 6 mantuvieron igual afectación y 2 curación con aminosalicilatos. Conclusiones: Se observó un alto porcentaje (70,8%) de curación y mejoría endoscópica, asociado a adherencia y optimización del tratamiento.


Introduction: endoscopic mucosal healing in inflammatory bowel disease has been associated with sustained clinical remission and hospitalizations and surgery reduction, but it has been difficult to achieve, according to the literature. So, we decided to assess improvement in endoscopic mucosal in our inflammatory bowel disease patients. Purpose: endoscopic mucosal assess improvement in patients with inflammatory bowel disease. Methods: multicenter, descriptive and transversal. We included 24 patients with IBD between 17-73 years. Control colonoscopy was performed to evaluate the response to treatment using endoscopic Mayo Score for ulcerative colitis, Simplified Score for Crohn’s disease and postoperative recurrence was evaluated with Rutgeerts Index endoscopic healing was considered when the patient had grade 0 at all scales and improvement when they had one point less in the endoscopy scale in decreased relation to the previous study. Results: ulcerative colitis: 12 patients, 10 received aminosalicylates and 2 biological therapy. The group receiving aminosalicylates, 3 had endoscopic healing, there was endoscopic improvement in 8 of which 6 are aminosalicylates and 2 Infliximab. There was one patient with no improvement aminosalicylates. Crohn’s Disease: 12 patients, 7 with aminosalicylates, 2 biological therapy alone, 2 with biological and immunomodulatory and 1 with biological and aminosalicylates. Of which 4 had endoscopic improvement, 12 stayed the same degree of involvement and 2 with aminosalicylates was endoscopic healing. Conclusions: There was a high percentage (70.8%) of healing and endoscopic improvement associated with adherence and treatment optimization.

8.
Artigo em Espanhol | LILACS | ID: lil-708443

RESUMO

El siguiente artículo se enmarca en el Proyecto de Investigación UBACyT: "Proyectos terapéuticos bajo la clínica psicoanalítica en el hospital público" cuyo objetivo principal es establecer la eficacia de los tratamientos psicoterapéuticos, conducidos desde la perspectiva del psicoanálisis, en un período de 16 entrevistas realizadas en el Servicio de Salud Mental del Hospital Central de San Isidro (Provincia de Buenos Aires, Argentina). En este trabajo nos centraremos en la variable "tiempo" con el propósito de circunscribir la función del tiempo lógico en psicoanálisis, subrayar su valor clínico e interrogar su posible articulación con el tiempo de tratamiento institucional. Para ello hemos tomado como referencia el escrito de J. Lacan "El tiempo lógico y el aserto de certidumbre anticipada. Un nuevo soisma", único escrito dedicado específicamente a desarrollar la noción de tiempo lógico.


The following article is part of the Research Project UBACyT: 'Therapeutic projects under the psychoanalytic clinic in public hospital" whose main objective is to establish the eficiency of psychotherapeutic treatments conducted from the perspective of psychoanalysis in a period of 16 interviews carried out at the Department of Mental Health at the Central Hospital of San Isidro (Buenos Aires Province, Argentina). In this paper we focus on the "time" variable in order to circumscribe the role of logical time in analysis, underline its clinical value and examine its possible joint with institutional treatment time. So we've taken as a reference the article "The logical time and the assertion of anticipated certainty, a new sophism ", written by J. Lacan, the only specifically dedicated to develop the notion of logical time.

9.
Artigo em Espanhol | BINACIS | ID: bin-128216

RESUMO

El siguiente artículo se enmarca en el Proyecto de Investigación UBACyT: "Proyectos terapéuticos bajo la clínica psicoanalítica en el hospital público" cuyo objetivo principal es establecer la eficacia de los tratamientos psicoterapéuticos, conducidos desde la perspectiva del psicoanálisis, en un período de 16 entrevistas realizadas en el Servicio de Salud Mental del Hospital Central de San Isidro (Provincia de Buenos Aires, Argentina). En este trabajo nos centraremos en la variable "tiempo" con el propósito de circunscribir la función del tiempo lógico en psicoanálisis, subrayar su valor clínico e interrogar su posible articulación con el tiempo de tratamiento institucional. Para ello hemos tomado como referencia el escrito de J. Lacan "El tiempo lógico y el aserto de certidumbre anticipada. Un nuevo soisma", único escrito dedicado específicamente a desarrollar la noción de tiempo lógico.(AU)


The following article is part of the Research Project UBACyT: Therapeutic projects under the psychoanalytic clinic in public hospital" whose main objective is to establish the eficiency of psychotherapeutic treatments conducted from the perspective of psychoanalysis in a period of 16 interviews carried out at the Department of Mental Health at the Central Hospital of San Isidro (Buenos Aires Province, Argentina). In this paper we focus on the "time" variable in order to circumscribe the role of logical time in analysis, underline its clinical value and examine its possible joint with institutional treatment time. So weve taken as a reference the article "The logical time and the assertion of anticipated certainty, a new sophism ", written by J. Lacan, the only specifically dedicated to develop the notion of logical time.(AU)

11.
GEN ; 66(2): 81-85, jun. 2012. ilus
Artigo em Espanhol | LILACS | ID: lil-664207

RESUMO

El hepatocarcinoma es la neoplasia primaria hepática más frecuente con una incidencia creciente en todo el mundo cuyo pronóstico está ligado con el diagnóstico temprano. Determinar la frecuencia del hepatocarcinoma en pacientes del Servicio de Gastroenterología del Hospital Militar "Dr. Carlos Arvelo" durante el período 2006-2011. Trabajo retrospectivo y descriptivo. Se recolectaron historias médicas de 39 pacientes con ese diagnóstico. Los rasgos demográficos fueron similares a los descritos en Occidente: predominio hombres (71,79%), edad promedio entre 60 y 69 años (35,8%). La primera causa fue por hepatitis C (35,89%), seguida por el alcohol (25,64%) y hepatitis B (15,38%). Para estadificación se usaron los criterios Barcelona Clinic Liver Cancer, siendo al momento del diagnóstico el estadio D el más frecuente (68,57%). El 28,20% recibió tratamiento. Sorafenib fue lo más utilizado, (7 pacientes) dado que ingresaban al Hospital en estadio terminal limitando las opciones terapéuticas. El 12,8% de los pacientes estaban vivos al momento de realizar el estudio. El hepatocarcinoma es un tumor raro en nuestro medio. Frecuentemente produce pocos síntomas, manifestándose como descompensación de la función hepática en pacientes con cirrosis por lo que debe intensificarse la pesquisa, para lograr diagnóstico temprano y mejorar el pronóstico


Hepatocellular carcinoma is the most common primary neoplasm liver with an increasing incidence worldwide whose prognosis is linked to early diagnosis. To determine the frequency of hepatocellular carcinoma in patients from the Gastroenterology Service of the Military Hospital "Dr. Carlos Arvelo" during the period 2006-2011. Retrospective and descriptive. Were collected from medical records of 39 patients with that diagnosis. The demographic features were similar to those described in the West: predominantly men (71.79%), average age between 60 and 69 (35.8%). The first cause was hepatitis C (35.89%), followed by alcohol (25.64%) and hepatitis B (15.38%). For staging criteria were used Barcelona Clinic Liver Cancer, being at the time of diagnosis, stage D the most common (68.57%). The 28.20% received treatment. Sorafenib was the most used, (7 patients) admitted to the hospital since end-stage limiting therapeutic options. 12.8% of patients were alive at the time of the study. Hepatocellular carcinoma is a rare tumor in our environment. Often produces few symptoms, manifesting as decompensation of liver function in patients with cirrhosis and should be intensified screening to achieve early diagnosis and improve prognosis


Assuntos
Feminino , Hepatite/complicações , Neoplasias Hepáticas/diagnóstico , Neoplasias Hepáticas/etiologia , Neoplasias Hepáticas/patologia , Gastroenterologia , Hepatopatias
12.
GEN ; 64(4): 335-338, dic. 2010. tab
Artigo em Espanhol | LILACS | ID: lil-664518

RESUMO

La Gastrostomía Endoscópica Percutánea fue descrita por primera vez en 1980 y pronto tuvo gran auge por ser un método fácil, seguro y sencillo. El benefi cio principal es el de iniciar la alimentación enteral temprana y el de ser un procedimiento con bajo riesgo, bajo costo-benefi cio, con reducción de la estancia hospitalaria y menor riesgo de infección en comparación con la gastrostomía quirúrgica. Demostrar que la gastrostomía endoscópica percutánea es un método seguro con pocas complicaciones que pueden garantizar la alimentación de los pacientes con enfermedades que impiden la alimentación oral. Se colocaron 21 gastrostómos por vía percutánea utilizando la técnica PULL. De los 21 procedimientos realizados, 15 (71,42%) fueron pacientes masculinos y 6 (28,57%) femeninas, dentro de los cuales 6 cursaban con défi cit neurológico tipo enfermedad cerebro vascular (28,57%), 3 tumores esofágico estenosante (14,28%), 2 correspondieron a traumatismo craneoencefálico (9,5%), y 2 lesiones de ocupación de espacio cerebral (9,5%), el restante corresponde a un paciente por cada una de las siguientes patología con un porcentaje de 4,76 respectivamente: lesiones de ocupación de espacio a nivel medular, cáncer de nasofaringe, cáncer de amígdala, adenocarcinoma de unión esófago gástrica, tumor maxilar operado con limitación apertura bucal, cáncer epidermoide cuerda vocal, cáncer de laringe y fístula gastroesofágica. Entre los servicios con mayor solicitud del procedimiento se encuentra Neurología y Oncología con 6 cada uno (28,57% respectivamente), Neurocirugía 5 (23,80%), Gastroenterología 2 (9,5%), UTI 1(4,76%) y 1(4,76%) Ambulatorio. De estos 21 procedimientos realizados no tuvimos complicaciones antes, durante ni después de la colocación del gastrostómo...


Percutaneous Endoscopic Gastrostomy (PEG) was fi rst described in 1980, and soon became a boom as a result of being and easy, safe and simple method. The main benefi t is that of starting an early enteric feed and of being a low risk, low cost-benefi t procedure, with a reduced inpatient term and a lower risk of infection if compared with surgical gastrostomy. Demonstrating that percutaneous endoscopic gastrostomy is a safe method, with few complications, which may guarantee feeding patients with diseases preventing oral feeding. 21 PEG tubes were placed by using the PULL technique. Out of the 21 performed procedures, 15 (71.42%) were male patients and 6 (28.57%) were female, and 6 of them presented stroke-related neurological defi cits (28.57%), 3 stenosing esophageal tumors (14.28%), 2 corresponded to craneoencephalic trauma (9,5%) and 2 lesions of intracranial space occupation (9,5%); the rest corresponds to one patient per each of the pathologies below, with a 4.76 ratio respectively: spinal space occupying lesions, nasopharyngeal cancer, tonsil cancer, gastroesophageal junction adenocarcinoma, limitation of mouth opening after maxillary tumor surgery, vocal cord epidermoid cancer, larynx cancer, and gastroesophageal fi stula. Services that requested more the services were: Neurology and Oncology, 6 requests each (28.57%, relevantly), Neurosurgery: 5 (23.80%), Gastroenterology: 2 (9.5%), ICU: 1 (4.76%), and Outpatient: 1 (4.76%). Of the 21 performed procedures, no complication arose either before, during or after placing the PEG tube...


Assuntos
Humanos , Masculino , Feminino , Endoscopia Gastrointestinal/métodos , Endoscopia Gastrointestinal , Gastroenteropatias , Gastroenterologia
13.
GEN ; 64(4): 353-355, dic. 2010. tab
Artigo em Espanhol | LILACS | ID: lil-664523

RESUMO

La trombosis venosa portal es una oclusión de la misma por un coágulo y/o trombo; o por otras causas como cirrosis, cáncer de hígado, páncreas o estómago. Afecta únicamente al tronco portal. En ausencia de un tumor maligno que invada o comprima el eje esplenoportal, la trombosis es el mecanismo etiopatogénico más frecuente que ocasiona la obstrucción venosa. Según las series estudiadas en un 7%-22% de los pacientes con trombosis portal no se identifica una condición protrombótica (trombosis portal idiopática). No obstante, en el resto de ocasiones en un 40% de casos existe un factor local desencadenante y en un 60% de casos restantes factores trombogénicos sistémicos. En más de un 15 % de estos pacientes coexisten factores etiológicos múltiples. Las consecuencias clínicas de la trombosis venosa del eje esplenoportal dependen del momento evolutivo en el que se encuentre ésta, pero también de la extensión del trombo. La principal manifestación suele ser el dolor abdominal, con frecuencia irradiado a espalda. Pueden aparecer síntomas inespecíficos como fiebre sin foco conocido, síntomas dispépticos (náuseas y plenitud postprandial) y malestar general. Los parámetros de función hepática, albúmina y tiempo de protrombina muestran mínimas alteraciones. En este trabajo quisimos exponer 4 casos de pacientes de nuestro centro a los cuales se les realizó el diagnóstico de trombosis de la vena porta, con edades comprendidas entre 30-60 años, con predominio del sexo masculino, y quienes han cumplido regularmente su tratamiento no presentando complicaciones durante su evolución, manteniéndose estables en su control entre 2003 y 2009...


Portal vein thrombosis is its occlusion by a clot and/or thrombus, or by other causes such as cirrhosis, cancer of liver, pancreas or stomach. It affects the portal trunk only. Whenever a malignant tumor invading or compressing the splenoportal axis is not present, thrombosis is the most frequent ethiopathogenetic mechanism causing vein obstruction. According to the studied series, in 7-22% of patients with portal thrombosis no prothrombotic condition (idiopathic portal thrombosis) is identified. However, in 40% of the remaining cases there is a local triggering factor, and the other 60% shows systemic thrombogenetic factors. Multiple etiologic factors coexist in over 15% of said patients. The clinical consequences of the splenoportal axis vein thrombosis depend on the evolution momentum where the thrombosis is found, and also on the thrombus’ dimension. Abdominal pain could be the main manifestation, frequently irradiated to the back. Non-specific symptoms could appear, such as fever of unknown origin, dyspeptic symptoms (nausea and postprandial fullness), and general malaise. The parameters of hepatic function, albumin, and of prothrombin time show minimal changes. In this study the cases of 4 patients of this health center were exposed; said patients were diagnosed with portal vein thrombosis and were of ages ranging 30-60, male-sex prevalence, who regularly followed their treatment and did not present complication in their evolution, staying stable in their 2003 and 2009 control...


Assuntos
Humanos , Masculino , Adulto , Feminino , Pessoa de Meia-Idade , Obstrução da Saída Gástrica/complicações , Obstrução da Saída Gástrica/patologia , Trombose Venosa/diagnóstico , Veia Porta/lesões , Gastroenterologia
14.
GEN ; 63(4): 266-271, dic. 2009. ilus, graf
Artigo em Espanhol | LILACS | ID: lil-664442

RESUMO

Los Linfomas No Hodgkin del tracto gastrointestinal son los linfomas extranodales más comunes, representando entre el 30 y 70% de esta última patología constituyendo un grupo heterogéneo de tumores con diferentes características clínicas y patológicas. El estómago está lesionado de manera predominante siendo los linfomas tipo MALT los tumores de bajo grado más frecuentes en el sistema gastrointestinal, contando con 40% de todos los linfomas gástricos primarios, manteniéndose localizados por períodos prolongados sin tratamiento. Objetivos: evaluar la epidemiología de los linfomas gastrointestinales en nuestro centro. Pacientes y métodos: Análisis retrospectivo de las historias de pacientes con diagnóstico de Linfoma Gastrointestinal. Resultados: Se presentan datos clínicos e histopatológicos de 20 pacientes con diagnóstico de Linfoma Gastrointestinal tratados en el Hospital Militar "Dr. Carlos Arvelo", Caracas, Venezuela, desde 2003 a 2008. 15 hombres, 5 mujeres, con edades comprendidas entre 23 y 64 años. De ellos, 14 (70 %) se presentaron con enfermedad limitada (estadio I-II) mientras que 6 (30%) tuvieron lesión de varios órganos (hígado, páncreas, bazo, duodeno) o más de un órgano gastrointestinal, siendo clasificado como estadio IV. 11 pacientes tuvieron linfoma gástrico, 2 de páncreas, 1 hepático esplénico y de columna lumbar, 1 intestino delgado, 1 en bazo, 4 de colon, y en 5 pacientes se observaron multiples localizaciones en el sistema gastrointestinal. Dolor abdominal, hemorragia digestiva, pérdida de peso fueron los síntomas más frecuentes de presentación. El estómago fue el órgano mas frecuentemente lesionado.


Non-Hodgkin´s lymphomas (NHL) of the gastrointestinal (GI) tract are the most common extra nodal lymphomas. They represent between 30% to 70% of all extra nodal lymphomas and constitute a heterogeneous group of tumors with different clinical and pathological features. The stomach is predominantly involved. MALT type lymphomas are the most frequent low grade non-Hodgkin´s lymphomas encountered in the GI tract. They account for 40% of all primary gastric lymphomas and remain, in the majority of cases, localized for a prolonged period of time without therapy. Aim: To evaluate the epidemiology of gastrointestinal lymphomas in our Hospital. Patients and Methods: Retrospective analysis of patientÊs recorders performed at the Hospital Militar "Dr. Carlos Arvelo", Caracas, that had the diagnosis of gastrointestinal lymphoma. Results Clinical and histopathologjcal data from 20 patients presenting with GI-NHL treated from 2003 until 2008, were reviewed. 15 men, 5 women with an age range between 23 and 64 years old. Of these, 14 (70%) presented with limited disease (stage I and II), while 6 patients were found to have disease involvement of other abdominal organs (i.e., liver, pancreas, spleen, duodenum) or more than one gastrointestinal site and were therefore classified as stage IV. 11 patients presented with lymphoma in the stomach, 2 pancreatic, 1 in liver, spleen and lumbar vertebrae, 1 in the small intestine and 4 in the large bowel, while in 5 cases multiple localizations of the gastrointestinal tract were documented. Abdominal pain, gastrointestinal bleeding, weighs loose were the main presenting symptom.

15.
Actas cardiovasc ; 8(2): 64-70, 1997. ilus
Artigo em Espanhol | LILACS | ID: lil-235139

RESUMO

Objetivo: Fundamentar los criterios de selección del tratamiento médico y/o quirúrgico en base a 180 pacientes con linfedema. Material y métodos: La linfografía radioisotópica dinámica se realizó siempre en los linfedemas secundarios con menos de 2 años de evolución y cuando se sospechó megalinfáticos. El eco-doppler color venoso se realizó sistemáticamente. Se efectuaron: 1 operación de Thompson modificada acorde en linfidema primario; 19 anastomosis linfo-venosas en linfidema secundario; 8 resecciones e injertos libres de piel en linfidema genital; 1 operación de Servelle. Ciento cincuenta y un pacientes fueron seleccionados para terapia médica descongestiva compleja como único tratamiento. Resultados: No se repitieron las crisis linfangíticas. El linfadema fue de más fácil control con tratamiento médico en su evolución alejada. Controló en este período el linfedema, sin recidiva. Permitió la deambulación. Los volúmenes se redujeron significativamente, acorde con la cooperación del paciente. Conclusiones: El tratamiento médico es la base de la terapia en linfedema. La cirugía tiene indicación: 1) en linfedemas gigantes (exéresis) para permitir la deambulación y controlar las crisis linfangíticas; 2) las anastomosis linfo-venosas son patrimonio de los linfedemas secundarios con vías funcionantes; 3) en el linfedema genital masculino la cirugía es el mejor tratamiento


Assuntos
Humanos , Masculino , Feminino , Linfedema/terapia , Anastomose Cirúrgica/tendências , Linfedema/cirurgia , Procedimentos Cirúrgicos Cardiovasculares , Resultado do Tratamento
16.
Actas cardiovasc ; 8(2): 64-70, 1997. ilus
Artigo em Espanhol | BINACIS | ID: bin-16089

RESUMO

Objetivo: Fundamentar los criterios de selección del tratamiento médico y/o quirúrgico en base a 180 pacientes con linfedema. Material y métodos: La linfografía radioisotópica dinámica se realizó siempre en los linfedemas secundarios con menos de 2 años de evolución y cuando se sospechó megalinfáticos. El eco-doppler color venoso se realizó sistemáticamente. Se efectuaron: 1 operación de Thompson modificada acorde en linfidema primario; 19 anastomosis linfo-venosas en linfidema secundario; 8 resecciones e injertos libres de piel en linfidema genital; 1 operación de Servelle. Ciento cincuenta y un pacientes fueron seleccionados para terapia médica descongestiva compleja como único tratamiento. Resultados: No se repitieron las crisis linfangíticas. El linfadema fue de más fácil control con tratamiento médico en su evolución alejada. Controló en este período el linfedema, sin recidiva. Permitió la deambulación. Los volúmenes se redujeron significativamente, acorde con la cooperación del paciente. Conclusiones: El tratamiento médico es la base de la terapia en linfedema. La cirugía tiene indicación: 1) en linfedemas gigantes (exéresis) para permitir la deambulación y controlar las crisis linfangíticas; 2) las anastomosis linfo-venosas son patrimonio de los linfedemas secundarios con vías funcionantes; 3) en el linfedema genital masculino la cirugía es el mejor tratamiento (AU)


Assuntos
Humanos , Masculino , Feminino , Linfedema/terapia , Linfedema/cirurgia , Resultado do Tratamento , Anastomose Cirúrgica/tendências , Procedimentos Cirúrgicos Cardiovasculares/estatística & dados numéricos
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