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J Neurol Sci ; 118(1): 25-8, 1993 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-8229047

RESUMO

To elucidate the possible role of vitamin C in the risk for developing Parkinson's disease (PD), we compared serum levels of ascorbic acid (vitamin C), measured by a fluorometric method, of 63 PD patients using their spouses as the control group. The serum levels of vitamin C did not differ significantly between the groups (47.13 +/- 0.89 micrograms/ml for PD and 47.60 +/- 0.60 micrograms/ml for controls). There was no influence of antiparkinsonian therapy on vitamin C. Serum levels of vitamin C did not correlate with age, age at onset and duration of the disease, scores of the Unified PD Rating Scale or the Hoehn and Yahr staging in the PD group. These results suggest that serum vitamin C concentrations are apparently unrelated to the risk of developing PD.


Assuntos
Ácido Ascórbico/sangue , Doença de Parkinson/sangue , Fatores Etários , Idade de Início , Idoso , Ácido Ascórbico/uso terapêutico , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Doença de Parkinson/tratamento farmacológico , Fatores de Risco , Espectrometria de Fluorescência
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