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1.
Bol Med Hosp Infant Mex ; 37(3): 409-12, 1980.
Artigo em Espanhol | MEDLINE | ID: mdl-7397021

RESUMO

Using antibodies against Toxoplasma gondii labelled with indium-113 metaestable we obtained scan of rats infested with this disease in a simple and harmless way. Also using the same antibodies, but labelled with iodine-131, we destroyed by radiolysis the toxoplasmas of experimental animals with the Medial Lethal Dose obtained "in vitro" experiments. The experimental results are very encouraging and their use in human beings are in currently research in our laboratory and will be the object of a future communication.


Assuntos
Anticorpos/administração & dosagem , Índio/uso terapêutico , Radioisótopos do Iodo/uso terapêutico , Radioisótopos/uso terapêutico , Toxoplasmose/diagnóstico por imagem , Toxoplasmose/radioterapia , Animais , Rotulagem de Medicamentos , Técnicas In Vitro , Dose Letal Mediana , Cintilografia , Ratos
2.
Bol Med Hosp Infant Mex ; 37(3): 413-6, 1980.
Artigo em Espanhol | MEDLINE | ID: mdl-7397022

RESUMO

Using the same technique that gave such good results in cysticercosis and other parasitic diseases we obtained antibodies labelled against trichinosis and proved their diagnostic value by scan in infected rats. These same antibodies at lethal dose, median, (LD50) radiolysed trichina larvae without damage to the animal. Experimental results are very encouraging and their potential use in human subjects are undergoing research in our laboratory and will be the object of a future report.


Assuntos
Anticorpos/administração & dosagem , Radioisótopos do Iodo/uso terapêutico , Triquinelose/diagnóstico por imagem , Triquinelose/radioterapia , Animais , Rotulagem de Medicamentos , Dose Letal Mediana , Cintilografia , Ratos
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