Assuntos
Transtorno Autístico/etiologia , Dano Encefálico Crônico/congênito , Deficiência Intelectual/etiologia , Gânglios da Base/fisiopatologia , Dano Encefálico Crônico/complicações , Pré-Escolar , Eletroencefalografia , Potenciais Evocados , Feminino , Humanos , Transtornos dos Movimentos/etiologia , Neurotransmissores/fisiologia , SíndromeRESUMO
The ultrastructure of the round window membrane of the cat was investigated. Three distinct layers were recognised and described. It was established that the outer epithelial layer is non-ciliated, but often contains microvilli. The middle layer, under the basement membrane, contains a large amount of collagen and elastic fibres in addition to fibrocytes. The inner layer is a continuation of the epithelial layer of the perilymphatic space. The thickness of the membrane has been measured as being 15--20 micrometer. The latest human audiological and clinical observations concerning the function and rupture of the round window membrane emhasise the importance of the electron microscopic study of this membrane.
Assuntos
Cóclea/ultraestrutura , Janela da Cóclea/ultraestrutura , Animais , Gatos , Membrana Celular/ultraestrutura , Cílios/ultraestrutura , Colágeno , Tecido Conjuntivo/ultraestrutura , Citoplasma/ultraestrutura , Tecido Elástico/ultraestrutura , Epitélio/ultraestrutura , Feminino , Masculino , Membranas/ultraestruturaRESUMO
Cochlear- and vestibular function were investigated in 72 patients, aged between 4 and 7 years who had neonatal hyperbilirubinaemia. Markedly more and more serious damage was found in the group of patients, who as neonates had serum bilirubin levels above 25 mg-%. The frequency of loss of cochlear and vestibular function was significantly higher in patients with hyperbilirubinaemia for more than 4 days. Contrary to data published until now, it can be concluded that the vestibular apparatus is the most sensitive part of the nervous system to bilirubin.
