RESUMO
Chocolate agar with teicoplanin disk (30 micrograms) was used for the isolation of Haemophilus strains. Fifty strains of 3 Haemophilus species grew as well in the inhibition zones of teicoplanin disks as on teicoplanin containing selective plates, whereas Gram-positive bacteria failed to form colonies. This selective method proved especially advantageous when Haemophilus strains were isolated from mixed bacterial cultures of 665 specimens.
Assuntos
Antibacterianos/farmacologia , Haemophilus/efeitos dos fármacos , Teicoplanina/farmacologia , Resistência Microbiana a Medicamentos , Haemophilus/isolamento & purificação , HumanosRESUMO
The sensitivity of haemophilus strains isolated from patients freshly were tested by newly produced fluorokinolones with broader antimicrobial activity and excellent pharmacokinetic features. We found a high sensitivity of all haemophilus strains tested by ofloxacin with Resistest method. The minimal inhibitory concentrations in Levinthal bouillon medium ranged between 0,015-0,03 micrograms/ml and the exerted a bactericidal effect. Since these concentrations are only a small portion of the blood and tissue levels of the ofloxacin, therefore the fluorokinolones proved to be effective antibacterial drugs in the therapy of the haemophilus infections.
