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1.
An Med Interna ; 6(6): 305-8, 1989 Jun.
Artigo em Espanhol | MEDLINE | ID: mdl-2491554

RESUMO

The serum of 18 patients diagnosed as having chronic active hepatitis (CAH) was studied in order to ascertain the neutrophil motility in healthy person serum. The chemotaxis and the chemokinesis induced by the serum of the patients were lower than those obtained using a control serum. When the control serum, activated by zymosan, was added to the patients serum a decrease of chemotaxis was observed. Contrary to this, when activated serum of patients was added to the control serum, there was no alteration of chemotaxis. We concluded that serum of patients affected by CAH have an inhibitor of the motility of neutrophils.


Assuntos
Quimiotaxia de Leucócito , Hepatite Crônica/sangue , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Neutrófilos/patologia , Zimosan/farmacologia
2.
An Med Interna ; 6(4): 192-6, 1989 Apr.
Artigo em Espanhol | MEDLINE | ID: mdl-2491521

RESUMO

51 patients with mild essential hypertension (EH) were randomly divided into two groups; the first group (31 patients) was treated with 1 g. of oral calcium during a period of 8 weeks; the second group received a placebo. The treated with calcium showed a significant decrease in blood pressure (BP), the maximal reduction being of 6 mm Hg in the systolic pressure (SBP) and 3 mm in the diastolic (DBP) at the end of the 8th week. We found a substantial positive relationship between the decrease in SBP and seric renin activity (p less than 0.05), as well as a significant negative relationship (p less than 0.05) between DBP and the seric level of parathyroid hormone (PTH). During the administration of the oral calcium supplement, the BP decreased in an inverse proportion to the plasmatic renin and seric level of PTH.


Assuntos
Cálcio/uso terapêutico , Hipertensão/tratamento farmacológico , Administração Oral , Adulto , Pressão Sanguínea/efeitos dos fármacos , Calcitonina/sangue , Cálcio/administração & dosagem , Cálcio/sangue , Cálcio/farmacologia , Feminino , Humanos , Hipertensão/fisiopatologia , Masculino , Pessoa de Meia-Idade , Hormônio Paratireóideo/sangue , Renina/sangue , Renina/deficiência
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