[Value of clear cell likelihood score in differentiation between renal oncocytoma and clear cell renal cell carcinoma].

Objective: To evaluate the value of clear cell likelihood score (ccLS) in identifying renal oncocytoma (RO) and clear cell renal cell carcinoma (ccRCC). Methods: Retrospective data of pathologically confirmed 43 RO patients [24 men and 19 women, aged 22-77 (54±14) years] between February 2008 and September 2021 and 43 ccRCC patients [30 men and 13 women, aged 29-78 (56±12) years] between May and July 2021 were consecutively included in the department of radiology, Chinese PLA General Hospital. Two radiologists used ccLS to assess each case independently, and disagreements were resolved by consensus. The ability of ccLS to identify RO and ccRCC was examined by the receiver operating characteristic (ROC) curve which identified the best optimal diagnostic cut-off values, sensitivity, specificity, accuracy, positive predictive value, and negative predictive value. Results: The mean tumor diameter was 3.8 cm in RO patients and 3.7 cm in ccRCC patients. Central scar and segmental enhancement inversion (SEI) were more frequently observed in the RO group compared to the ccRCC group [53.5% (23∶43) versus 11.6% (5∶43) and 41.9% (18∶43) versus 7.0% (3∶43), respectively], with statistical differences (P<0.001). The ccLS scores in the RO group ranged from 1 to 4, while 79.0% of the cases were 3. The ccLS scores in the ccRCC group ranged from 2 to 5, while 72% of the cases were 4. The scores of the two groups were statistically different (P<0.001). The ccLS showed the best performance when the threshold was 4 according to the ROC curve. The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of ccLS for distinguishing RO from ccRCC were 83.7%, 90.7%, 87.2%, 90.0%, and 84.8%, respectively, and the area under the ROC curve value was 0.879. Conclusion: The ccLS has credible sensitivity and specificity in differentiating renal oncocytoma from clear cell carcinoma, which may be helpful for the preoperative diagnosis.

[Investigation on demands for antenatal care services among 2 002 pregnant women during the epidemic of COVID-19 in Shanghai].

Objective: To identify problems and demands for antenatal care (ANC) among pregnant women in different trimesters of pregnancy in Shanghai for optimizing ANC service during the epidemic of COVID-19. Method: s Organized by maternal and child health care institute in the 16 districts of Shanghai, a cross sectional study was conducted among pregnant women who came to pregnancy registration in the community health centers or attended ANC in midwifery hospitals from February 7 to February 12, 2020. Consented participating women completed a semi-structured online questionnaire voluntarily. Data was analyzed using frequency,chi-square test and scoring. Result: s A total of 2 002 valid questionnaires were collected from 183 community health centers and 67 midwifery hospitals. About 94.6%(1 894/2 002) of the pregnant women worried about being infected during the COVID-19 epidemic, and 14.7% (294/2 002) demanded for psychological consultation. Time-lapse appointments for ANC were requested by 87.7% (1 756/2 002) of the participants for avoiding presenting themselves in people-density places. Compared with other pregnancy trimesters, pregnant women in the second trimester were more willing to reduce the frequency of ANC (35.2% versus 39.5% versus 48.1%, P<0.01). Compared with multiparas, primiparas were more willing to have online consultation and guidance (49.2% versus 63.8%, P<0.01). Regarding the needs for health knowledge on COVID-19, personal protection against 2019 novel coronavirus (2019-nCoV) was the most concerned for pregnant women, and 71.0% (1 421/2 002) of them preferred to obtain knowledge through health applications, official Weibo and WeChat. Conclusions: Pregnant women in Shanghai critically concern about the risk of 2019-nCoV infections, and highly demand knowledge and measures on prevention and protection from COVID-19. They ask for having time-lapse appointments for ANC and online access to health information and services. Maternal and child care institutes should understand the demands of pregnant women, optimize the means of ANC service, and provide tailored and accessible health education and service for the safety of mother and child.

The mechanism of Al donor defects in (Zn, Co)O:Al: a view from resonant x-ray spectroscopies.

We studied the effect of Al doping in Zn(0.94)Co(0.05)Al(0.01)O nano-powders from the electronic structure point of view by applying x-ray absorption spectroscopy and resonant inelastic x-ray scattering at the oxygen K- and Co L-edges. The intensity of the pre-edge structure of the O-K XAS spectra is enhanced following the introduction of the Al defect. Multiple scattering calculations demonstrate it can be accounted for by the gain of the hybridization strength between O 2p and Al 3p (and/or Co 3d) states. The consensus on the hybridization strength is reached by combining Co-L XAS and RIXS investigations and multiplet calculations. It reveals different spatial substitutions of Al doping can alter the number of shared oxygen atoms between the Co and Al tetrahedrons. These shared ligands are responsible for the Al 3p and Co 3d state hybridization strength as well as the ferromagnetism of the ground state. The magnetic difference is better understood to be governed by various shared oxygen atoms rather than the distance between the Al defect and Co impurities.

Dysprosium compounds studied by resonant inelastic X-ray scattering and high-resolution X-ray absorption near edge structure spectroscopy.

A set of resonant inelastic X-ray scattering (RIXS) studies focusing on the 2p64f(n)-->2p54f(n)5d1(2p54f(n+1)5d0)-->2p63d94f(n)5d1(2p63d94f(n+1)5d0) channel of dysprosium in Dy metal, Dy2O3, DyNi3 and Dy25Fe18 compounds have been carried out. Data showed with high statistics and resolution, the different delocalization degree of the 5d band of dysprosium in these compounds, e.g., decreasing from Dy metal to DyNi3, Dy25Fe18 and to dysprosium oxide, in agreement with the high-resolution XANES (HRXANES) spectra. Band structure calculations performed on Dy metal and Dy2O3 confirm both RIXS and HRXANES results in the increasing delocalization of the dysprosium 5d band in Dy metal with respect to Dy2O3. The 5d orbital occupancies of DyNi3 and Dy25Fe18 alloys have been also studied by comparison of the HRXANES white line (WL) area with the behavior of the final states energy position in RIXS spectra and we show that DyNi3 has a higher 5d orbital occupancy than Dy25Fe18.