Ultrasonic dissection versus electrocautery in mastectomy for breast cancer - a meta-analysis.

BACKGROUND: Electrocautery has advanced the practice of mastectomy but significant morbidity, such as seroma and blood loss, remains a concern. This has led to newer forms of dissection being introduced including the ultrasonic dissection devices, which are thought to reduce tissue damage. The aim of this systematic review was to compare the outcomes after mastectomy using novel ultrasonic dissection or standard electrocautery in published trials. METHODS: Medline, Embase, trial registries, conference proceedings and reference lists were searched for comparative trials of ultrasonic dissection versus electrocautery for mastectomy. The primary outcomes were total postoperative drainage, seroma development and intra-operative blood loss. Secondary outcomes were operative time and wound complications. Odds ratios were calculated for categorical outcomes and standardised mean differences for continuous outcomes. RESULTS: Six trials were included in the analysis of 287 mastectomies. There was no effect in total postoperative drainage (pooled analysis weight mean difference: -0.21 (95% CI: -0.70-0.29); p = 0.41) or seroma development (pooled analysis odds ratio: 0.77 (95% CIs 0.43-1.37); p = 0.37). Intra-operative blood was slightly less for ultrasonic dissection compared to standard electrocautery (pooled analysis weight mean difference: -1.04 (95% CI: -2.00 to -0.08); p = 0.03). Ultrasonic dissection and standard electrocautery had similar outcomes with regard to operative time and wound complications. CONCLUSION: Ultrasonic dissection and standard electrocautery appear to deliver similar results in the mastectomy setting. Further cost-effectiveness analysis may guide surgeon selection in the use of new technologies for mastectomy.

Ovulating ovary in an inguinal hemia.

BACKGROUND: An ovary can, occasionally, be found in an inguinal hernia in the newborn female. This is extremely rare in premenopausal women. We report a case of an ovulating ovary in an incarcerated inguinal hernia. There is only one similar case of incarcerated ovulating ovary reported in the literature. METHOD AND FINDINGS: A 23-year-old Turkish woman, mother of three children, presented with a painful swelling over the upper part of left labia majora of 48 hours duration. She was diagnosed as having an obstructed left inguinal hernia. At operation the left ovary and fallopian tube were seen in the left inguinal canal. The ovary and fallopian tube were congested but viable and mature ovarian follicles could be seen on the ovary. A biopsy was taken from the ovary, the ovary and the fallopian tube were easily reduced back into the abdominal cavity and the hernia repaired. DISCUSSION: The presence of an ovary in the inguinal canal is very rare and should be a differential diagnosis in women presenting with an irreducible lump in the inguinal area. It should be treated as a surgical emergency.

Intra-operative specimen analysis using faxitron microradiography for excision of mammographically suspicious, non-palpable breast lesions.

Recent advances in digital imaging have made Faxitron microradiography an attractive alternative to intra-operative conventional specimen radiography (CSR) for the excision of wire-localized breast lesions. Faxitron specimen analysis time, usefulness of digital image manipulation and re-excision rates were evaluated in comparison to CSR in 299 consecutive wire-localized excisions for mammographically suspicious non-palpable breast lesions (172 procedures with Faxitron, 127 with CSR) in a non-randomized study. The corresponding mean operation times were 34.7 vs. 42.7 min and the respective re-excision rates were 19.8% vs. 31.5% (no significant difference on chi analysis P < 0.1). Faxitron digital image manipulation led to cavity biopsies in 50% (60/121) of the cancer excisions. In 19 of these (16%), histological excision margins were converted from incomplete to complete. The shorter Faxitron mean operating time enables an additional wire-localized operation per theatre list. Digital imaging guides the surgeon for additional cavity biopsies, resulting in re-excision rates as good as CSR.