RESUMO
OBJECTIVE: To assess the prevalence of prenatal exposure to cocaine in a sample of newborns using two methods: fluorescence polarization immunoassay and interview with the mother. METHODS: This cross-sectional study was carried out in a university teaching hospital. The population included all live births between March 23, 1999 and June 01, 1999 (n=847). Exposure was determined by a benzoylecgonine-positive meconium specimen and/or by a positive interview with the mother. RESULTS: The prevalence of prenatal exposure to cocaine in this sample was 2.4% (16 cases) according to the interviews, and 3.4% (25 cases) according to the meconium analysis. A rate of 4.6% (34 cases) was found when both methods were associated. CONCLUSIONS: We observed that the meconium test was more effective than the maternal interview for the diagnosis of prenatal exposure to cocaine. The meconium analysis enhanced diagnostic chances by 53.4%, compared to 26% in the case of maternal interview.
RESUMO
OBJECTIVE: To study prenatal cocaine exposure, emphasizing its behavioral effects. METHODS: Literature review of the last 15 years, through Medline and direct search. RESULTS AND CONCLUSIONS: According to the literature, the incidence of prenatal cocaine exposure is up to 15.5%, and its effects on the newborn are particularly on the development of the nervous system. Pediatricians and sub-specialists must know the consequences of such exposure in order to diagnose and affect the prognosis of these children.
RESUMO
Os autores procederam a um levantamento aos prontuarios de 20.230 internacoes feitas na Clinica Obstetrica do Hospital Geral de Goiania-INAMPS, no periodo de marco de 1974 a fevereiro de 1982, encontrando 27 casos com o diagnostico clinico de cardiopatia. Tecem consideracoes sobre a conduta obstetrica seguida nesses casos
