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J Neuropsychiatry Clin Neurosci ; 13(1): 77-87, 2001.
Artigo em Inglês | MEDLINE | ID: mdl-11207333

RESUMO

EEG spectral analyses were conducted from 19 scalp locations for patients with mild (n=40), moderate (n=25), and severe (n=43) traumatic brain injury (TBI), 15 days to 4 years after injury. Severity of TBI was judged by emergency hospital admission records (Glasgow Coma Score and duration of coma and amnesia). Highest-loading EEG variables on each factor that differed significantly between severe and mild TBI by univariate t-test were entered into a multivariate discriminant analysis, yielding 16 variables. Discriminant analysis between mild and severe TBI groups showed classification accuracy of 96.39%, sensitivity 95.45%, and specificity 97.44%. The EEG discriminant score also measured intermediate severity in moderate TBI patients. Results were cross-validated in 503 VA patients. Significant correlations between EEG discriminant scores, emergency admission measures, and post-trauma neuropsychological test scores validated the discriminant function as an index of severity of injury and a classifier of the extremes of severity.


Assuntos
Dano Encefálico Crônico/diagnóstico , Lesões Encefálicas/diagnóstico , Eletroencefalografia , Adolescente , Adulto , Dano Encefálico Crônico/fisiopatologia , Lesões Encefálicas/fisiopatologia , Feminino , Seguimentos , Análise de Fourier , Escala de Coma de Glasgow , Humanos , Masculino , Pessoa de Meia-Idade , Testes Neuropsicológicos , Sensibilidade e Especificidade , Processamento de Sinais Assistido por Computador
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