1.
Chem Commun (Camb)
; 51(86): 15696-9, 2015 Nov 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26364843
RESUMO
Phytofurans are novel metabolites produced by non-enzymatic peroxidation of α-linolenic acid. An unprecedented Payne rearrangement-cyclization of a C2-symmetric bis-epoxide permitted construction of the core 3-hydroxy-2,5-disubstituted tetrahydrofuran. LC-MS/MS investigation provided evidence for the presence of phytofurans in nuts and seeds for the first time.